Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.37 (neutrophil elastase)
4,078 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
neutrophil elastase 2998
HNE 828
cathepsin G 480
Sep 315
myeloperoxidase 293
Mol 269
elastin 249
chymotrypsin 233
serine protease 221
thrombin 211
alpha 1-antitrypsin 188
proteinase 3 184
protease inhibitor 164
IL-8 149
cytokine 148
Pseudomonas 138
collagen 119
granulocyte 113
lipopolysaccharide 99
elastase inhibitor 83
secretory leukocyte protease inhibitor 82
SDS 82
serine protease inhibitor 81
tumor necrosis factor 79
elafin 74
fibronectin 73
albumin 71
matrix metalloproteinase 70
glycoprotein 69
C-reactive protein 68
trypsin inhibitor 66
IL-6 65
TNF 64
MMP-9 60
fibrinogen 59
serine proteinase inhibitor 59
mucin 54
kallikrein 50
lactoferrin 50
Met 50
more...
Disease
emphysema 341
cystic fibrosis 234
chronic obstructive pulmonary disease 169
cancer 108
lung disease 107
tumor 96
sepsis 93
SDS 87
neutropenia 83
sepsis 82
asthma 71
severe congenital neutropenia 71
adult respiratory distress syndrome 61
pneumonia 60
rheumatoid arthritis 59
ischemia 53
leukemia 53
AAT deficiency 49
liver disease 42
bronchiectasis 40
periodontitis 39
SEM 36
chronic bronchitis 35
acute myeloid leukemia 35
vasculitis 34
bacterial infection 32
atherosclerosis 31
diabetes 30
psoriasis 29
Wegener's granulomatosis 27
genetic disorder 27
disseminated intravascular coagulation 26
lung cancer 26
infectious diseases 25
COPD 24
pulmonary edema 24
arthritis 24
cirrhosis 22
acute promyelocytic leukemia 22
breast cancer 22
more...
Symptom
respiratory distress 57
anesthesia 23
pain 14
cough 9
dyspnea 9
diarrhea 9
hyperoxia 8
erythema 6
collapse 5
splenomegaly 3
hypothermia 3
headache 3
functional recovery 3
fatigue 3
constipation 2
BHS 2
starvation 2
ataxic gait 2
Air trapping 2
angina 2
disturbed balance 2
colic 1
twitching 1
nausea 1
nausea and vomiting 1
Welt 1
exertional dyspnea 1
abdominal discomfort 1
HSA 1
metamorphopsia 1
productive cough 1
anorexia 1
exhaustion 1
abdominal pain 1
stridor 1
cachexia 1
analgesia 1
weakness 1
bradypnea 1
syncope 1
more...
Drug
lysine 49
Dermatol 45
Sivelestat 37
CSF 30
Cardiovasc 25
ICI 25
G-CSF 19
Asn 18
Sivelestat sodium hydrate 17
Gel 15
DNase I 13
IL-2 11
Ulinastatin 11
Aprotinin 10
IFN-gamma 9
ROS 8
DFP 7
Asthma 7
EPI 7
ENT 7
Nephron 6
uPA 6
Nephron 6
vitamin E 6
Gelatin 6
ACT 5
Prolastin 5
Antithrombin III 4
Dial 4
MAP 4
CaCl2 4
CaCl2 4
CaCl2 4
ascorbate 4
Albumin 4
ABC 4
Glutathione 3
Areca 3
citric acid 3
Prednisolone 3
more...
Enzyme
neutrophil elastase 4078
elastase 1231
cathepsin G 470
trypsin 374
peroxidase 310
chymotrypsin 286
thrombin 206
plasmin 165
collagenase 90
kallikrein 86
mitogen-activated protein kinase 54
proteinase-3 53
urokinase-type plasminogen activator 52
tryptase 47
thromboplastin 45
aspartate aminotransferase 39
lysozyme 37
NADPH oxidase 37
NADPH oxidase 37
tissue plasminogen activator 36
MMP-3 33
cathepsin B 32
chymase 32
ERK 31
papain 30
matrix metalloproteinase 9 29
subtilisin 28
catalase 28
APC 26
protein kinase C 26
superoxide dismutase 23
DNase 23
macrophage elastase 23
pseudolysin 19
cathepsin L 19
lactate dehydrogenase 19
caspase-3 17
beta-glucuronidase 16
alanine aminotransferase 16
tissue kallikrein 15
more...
Compound
serine 521
Dec 306
DNA 255
Clin 244
oxygen 189
alanine 172
Phe 121
sodium 117
methionine 107
acetate 103
leucine 100
sulfate 96
arginine 95
calcium 89
SDS 88
lysine 81
water 66
TNF 64
cysteine 57
valine 57
His 46
hydrogen 42
salt 41
tyrosine 40
NH2 39
Gly 35
Pac 35
nitrogen 33
Serine 32
AAT 32
Ile 32
H2O2 32
phosphate 32
nitric oxide 28
Asp 27
EDTA 26
Heparin 26
EDTA 26
ICI 25
glucose 24
more...