Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.37 (
neutrophil elastase
)
4,078
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
neutrophil elastase
2998
HNE
828
cathepsin G
480
Sep
315
myeloperoxidase
293
Mol
269
elastin
249
chymotrypsin
233
serine protease
221
thrombin
211
alpha 1-antitrypsin
188
proteinase 3
184
protease inhibitor
164
IL-8
149
cytokine
148
Pseudomonas
138
collagen
119
granulocyte
113
lipopolysaccharide
99
elastase inhibitor
83
secretory leukocyte protease inhibitor
82
SDS
82
serine protease inhibitor
81
tumor necrosis factor
79
elafin
74
fibronectin
73
albumin
71
matrix metalloproteinase
70
glycoprotein
69
C-reactive protein
68
trypsin inhibitor
66
IL-6
65
TNF
64
MMP-9
60
fibrinogen
59
serine proteinase inhibitor
59
mucin
54
kallikrein
50
lactoferrin
50
Met
50
more...
Disease
emphysema
341
cystic fibrosis
234
chronic obstructive pulmonary disease
169
cancer
108
lung disease
107
tumor
96
sepsis
93
SDS
87
neutropenia
83
sepsis
82
asthma
71
severe congenital neutropenia
71
adult respiratory distress syndrome
61
pneumonia
60
rheumatoid arthritis
59
ischemia
53
leukemia
53
AAT deficiency
49
liver disease
42
bronchiectasis
40
periodontitis
39
SEM
36
chronic bronchitis
35
acute myeloid leukemia
35
vasculitis
34
bacterial infection
32
atherosclerosis
31
diabetes
30
psoriasis
29
Wegener's granulomatosis
27
genetic disorder
27
disseminated intravascular coagulation
26
lung cancer
26
infectious diseases
25
COPD
24
pulmonary edema
24
arthritis
24
cirrhosis
22
acute promyelocytic leukemia
22
breast cancer
22
more...
Symptom
respiratory distress
57
anesthesia
23
pain
14
cough
9
dyspnea
9
diarrhea
9
hyperoxia
8
erythema
6
collapse
5
splenomegaly
3
hypothermia
3
headache
3
functional recovery
3
fatigue
3
constipation
2
BHS
2
starvation
2
ataxic gait
2
Air trapping
2
angina
2
disturbed balance
2
colic
1
twitching
1
nausea
1
nausea and vomiting
1
Welt
1
exertional dyspnea
1
abdominal discomfort
1
HSA
1
metamorphopsia
1
productive cough
1
anorexia
1
exhaustion
1
abdominal pain
1
stridor
1
cachexia
1
analgesia
1
weakness
1
bradypnea
1
syncope
1
more...
Drug
lysine
49
Dermatol
45
Sivelestat
37
CSF
30
Cardiovasc
25
ICI
25
G-CSF
19
Asn
18
Sivelestat sodium hydrate
17
Gel
15
DNase I
13
IL-2
11
Ulinastatin
11
Aprotinin
10
IFN-gamma
9
ROS
8
DFP
7
Asthma
7
EPI
7
ENT
7
Nephron
6
uPA
6
Nephron
6
vitamin E
6
Gelatin
6
ACT
5
Prolastin
5
Antithrombin III
4
Dial
4
MAP
4
CaCl2
4
CaCl2
4
CaCl2
4
ascorbate
4
Albumin
4
ABC
4
Glutathione
3
Areca
3
citric acid
3
Prednisolone
3
more...
Enzyme
neutrophil elastase
4078
elastase
1231
cathepsin G
470
trypsin
374
peroxidase
310
chymotrypsin
286
thrombin
206
plasmin
165
collagenase
90
kallikrein
86
mitogen-activated protein kinase
54
proteinase-3
53
urokinase-type plasminogen activator
52
tryptase
47
thromboplastin
45
aspartate aminotransferase
39
lysozyme
37
NADPH oxidase
37
NADPH oxidase
37
tissue plasminogen activator
36
MMP-3
33
cathepsin B
32
chymase
32
ERK
31
papain
30
matrix metalloproteinase 9
29
subtilisin
28
catalase
28
APC
26
protein kinase C
26
superoxide dismutase
23
DNase
23
macrophage elastase
23
pseudolysin
19
cathepsin L
19
lactate dehydrogenase
19
caspase-3
17
beta-glucuronidase
16
alanine aminotransferase
16
tissue kallikrein
15
more...
Compound
serine
521
Dec
306
DNA
255
Clin
244
oxygen
189
alanine
172
Phe
121
sodium
117
methionine
107
acetate
103
leucine
100
sulfate
96
arginine
95
calcium
89
SDS
88
lysine
81
water
66
TNF
64
cysteine
57
valine
57
His
46
hydrogen
42
salt
41
tyrosine
40
NH2
39
Gly
35
Pac
35
nitrogen
33
Serine
32
AAT
32
Ile
32
H2O2
32
phosphate
32
nitric oxide
28
Asp
27
EDTA
26
Heparin
26
EDTA
26
ICI
25
glucose
24
more...