Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.37 (
neutrophil elastase
)
4,078
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
bactericidal/permeability-increasing protein-like 1
12.9
neutrophil elastase
12.9
HCLS1 protein
11.9
HNE
11.3
Skin-derived antileukoproteinase
11.1
elastase inhibitor
11.1
cathepsin G
11.0
elafin
10.9
SERPINB1
10.8
Alpha-1 antitrypsin
10.7
PFAAP5
10.6
secretory leukocyte protease inhibitor
10.6
SPINK9
10.3
GAP SH3 binding protein
10.3
ISP2
10.3
anti-elastase
10.2
CUX1 protein
10.1
SLPI
10.1
HTF1
9.9
JAGN1
9.9
more...
Disease
Chronic neutrophilia
11.9
Loss of skin elasticity
11.9
Chronic epididymitis
11.3
Pseudomonas bronchitis
10.9
Bronchopulmonary disease
10.9
Bacterial infections of the respiratory tract
10.3
severe congenital neutropenia
10.3
Fibrosing colonopathy
9.8
Cyclic neutropenia
9.7
unable to stop smoking
9.6
Elastolysis
9.5
AAT deficiency
9.3
Burkholderia cepacia infection
9.1
stage II cervical cancer
9.0
Acute viral bronchiolitis
8.9
ALHE
8.8
myometritis
8.6
Myelokathexis
8.6
XDP
8.6
Heartworm disease
8.5
more...
Symptom
inflammation of the tonsils
9.2
Air trapping
8.7
BHS
7.2
Skin symptoms
6.8
disturbed balance
6.1
bradypnea
5.3
metamorphopsia
5.0
ataxic gait
4.8
respiratory distress
4.5
Gastrointestinal symptoms
3.7
hyperoxia
3.6
microbial colonization
2.9
productive cough
2.8
Neuropathic pain
2.5
abdominal discomfort
2.2
twitching
1.9
flank pain
1.8
erythema
1.8
stridor
1.7
pallor
1.6
more...
Drug
Sivelestat
12.6
Sivelestat sodium hydrate
12.4
Talniflumate
10.9
Prolastin
9.9
Ulinastatin
9.6
Piclamilast
9.5
Piclamilast
9.5
Cilomilast
8.5
Camostat mesilate
8.1
Ocrelizumab
7.6
Pulmozyme
7.6
Rebamipide
7.3
Nafamostat mesilate
7.0
Hyperforin
6.9
Bexxar
6.8
Gabexate mesilate
6.7
Trifluoroethanol
6.7
Gold sodium thiomalate
6.6
Olmesartan medoxomil
6.5
Areca
6.4
more...
Enzyme
neutrophil elastase
12.9
cathepsin G
11.0
pseudolysin
11.0
macrophage elastase
10.3
proteinase-3
10.2
elastase
10.0
streptopain
9.3
aureolysin
9.3
granzyme M
9.1
neutrophil collagenase
8.8
peptidylarginine deiminase
8.1
serralysin
7.8
Streptomyces griseus protease B
7.8
alpha-lytic protease
7.7
prostasin
7.7
coagulation factor XIa
7.7
chymotrypsin
7.7
cathepsin C
7.7
chymase
7.5
PGE2 isomerase
7.3
more...
Compound
C26H28N4O9
12.9
C26H28N4O9
12.9
C24H40O4
12.9
C24H40O4
12.9
C24H40O4
12.9
C24H40O4
12.9
C24H40O4
12.9
C24H40O4
12.9
C24H40O4
12.9
C24H40O4
12.9
C24H40O4
12.9
C24H40O4
12.9
C24H40O4
12.9
dihydro-2(3H)-thiophenone
12.9
C24H40O4
12.9
C24H40O4
11.9
C24H40O4
11.9
Allochenodeoxycholic acid
11.3
2-phenyl-4H-3,1-benzoxazin-4-one
11.3
phenyl pivalate
11.3
more...