Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.37 (neutrophil elastase)
4,078 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
neutrophil elastase 2998
HNE 828
cathepsin G 480
Sep 315
myeloperoxidase 293
Mol 269
elastin 249
chymotrypsin 233
serine protease 221
thrombin 211
alpha 1-antitrypsin 188
proteinase 3 184
protease inhibitor 164
IL-8 149
cytokine 148
Pseudomonas 138
collagen 119
granulocyte 113
lipopolysaccharide 99
elastase inhibitor 83
more...
Disease
emphysema 341
cystic fibrosis 234
chronic obstructive pulmonary disease 169
cancer 108
lung disease 107
tumor 96
sepsis 93
SDS 87
neutropenia 83
sepsis 82
asthma 71
severe congenital neutropenia 71
adult respiratory distress syndrome 61
pneumonia 60
rheumatoid arthritis 59
ischemia 53
leukemia 53
AAT deficiency 49
liver disease 42
bronchiectasis 40
more...
Symptom
respiratory distress 57
anesthesia 23
pain 14
diarrhea 9
cough 9
dyspnea 9
hyperoxia 8
erythema 6
collapse 5
hypothermia 3
splenomegaly 3
headache 3
functional recovery 3
fatigue 3
disturbed balance 2
BHS 2
starvation 2
angina 2
constipation 2
Air trapping 2
more...
Drug
lysine 49
Dermatol 45
Sivelestat 37
CSF 30
ICI 25
Cardiovasc 25
G-CSF 19
Asn 18
Sivelestat sodium hydrate 17
Gel 15
DNase I 13
IL-2 11
Ulinastatin 11
Aprotinin 10
IFN-gamma 9
ROS 8
EPI 7
DFP 7
Asthma 7
ENT 7
more...
Enzyme
neutrophil elastase 4078
elastase 1231
cathepsin G 470
trypsin 374
peroxidase 310
chymotrypsin 286
thrombin 206
plasmin 165
collagenase 90
kallikrein 86
mitogen-activated protein kinase 54
proteinase-3 53
urokinase-type plasminogen activator 52
tryptase 47
thromboplastin 45
aspartate aminotransferase 39
NADPH oxidase 37
NADPH oxidase 37
lysozyme 37
tissue plasminogen activator 36
more...
Compound
serine 521
Dec 306
DNA 255
Clin 244
oxygen 189
alanine 172
Phe 121
sodium 117
methionine 107
acetate 103
leucine 100
sulfate 96
arginine 95
calcium 89
SDS 88
lysine 81
water 66
TNF 64
valine 57
cysteine 57
more...