Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.37 (
neutrophil elastase
)
4,078
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
neutrophil elastase
2998
HNE
828
cathepsin G
480
Sep
315
myeloperoxidase
293
Mol
269
elastin
249
chymotrypsin
233
serine protease
221
thrombin
211
alpha 1-antitrypsin
188
proteinase 3
184
protease inhibitor
164
IL-8
149
cytokine
148
Pseudomonas
138
collagen
119
granulocyte
113
lipopolysaccharide
99
elastase inhibitor
83
more...
Disease
emphysema
341
cystic fibrosis
234
chronic obstructive pulmonary disease
169
cancer
108
lung disease
107
tumor
96
sepsis
93
SDS
87
neutropenia
83
sepsis
82
asthma
71
severe congenital neutropenia
71
adult respiratory distress syndrome
61
pneumonia
60
rheumatoid arthritis
59
ischemia
53
leukemia
53
AAT deficiency
49
liver disease
42
bronchiectasis
40
more...
Symptom
respiratory distress
57
anesthesia
23
pain
14
diarrhea
9
cough
9
dyspnea
9
hyperoxia
8
erythema
6
collapse
5
hypothermia
3
splenomegaly
3
headache
3
functional recovery
3
fatigue
3
disturbed balance
2
BHS
2
starvation
2
angina
2
constipation
2
Air trapping
2
more...
Drug
lysine
49
Dermatol
45
Sivelestat
37
CSF
30
ICI
25
Cardiovasc
25
G-CSF
19
Asn
18
Sivelestat sodium hydrate
17
Gel
15
DNase I
13
IL-2
11
Ulinastatin
11
Aprotinin
10
IFN-gamma
9
ROS
8
EPI
7
DFP
7
Asthma
7
ENT
7
more...
Enzyme
neutrophil elastase
4078
elastase
1231
cathepsin G
470
trypsin
374
peroxidase
310
chymotrypsin
286
thrombin
206
plasmin
165
collagenase
90
kallikrein
86
mitogen-activated protein kinase
54
proteinase-3
53
urokinase-type plasminogen activator
52
tryptase
47
thromboplastin
45
aspartate aminotransferase
39
NADPH oxidase
37
NADPH oxidase
37
lysozyme
37
tissue plasminogen activator
36
more...
Compound
serine
521
Dec
306
DNA
255
Clin
244
oxygen
189
alanine
172
Phe
121
sodium
117
methionine
107
acetate
103
leucine
100
sulfate
96
arginine
95
calcium
89
SDS
88
lysine
81
water
66
TNF
64
valine
57
cysteine
57
more...