Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.37 (
neutrophil elastase
)
4,078
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Inflammatory diseases may lead to local tissue injury due to an imbalance between
leukocyte elastase
and protease inhibitors (alpha-1-antitrypsin, alpha-2-macroglobulin). Hence, we determined the plasma level of elastase in patients with
chronic tonsillitis
using an enzyme-linked immunoassay and compared the results with those obtained from controls. There was a significant elevation of
leukocyte elastase
in patients with chronic inflammation of the tonsils compared with our controls. The sensitivity and specificity of the elastase assay characterise this method as a reliable one. Hence, the determination of
leukocyte elastase
in peripheral blood can be useful if the indication for tonsillectomy is in question.
...
PMID:[Behavior of leukocyte elastase in chronic inflammatory tonsillar diseases]. 247 3
