Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.21.1 (chymotrypsin)
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Human Gene/Protein
CTRL protein 11.5
MiIX 11.5
protein DDX26B 11.5
chymotrypsin 11.4
elastase 2A 10.7
amyloid protein AL 10.5
aminopeptidase O 10.5
HLA-DRB1 protein 10.5
branched chain alpha-ketoacid dehydrogenase kinase 10.5
Chymotrypsin 10.5
pancreatopeptidase E 10.2
SPINK9 9.9
protease E) 9.9
testis-specific serine protease 1 9.9
Serine proteinase inhibitor 9.8
elastase 3B 9.7
AB18 9.5
GRP-preferring bombesin receptor 9.5
MC-CPA 9.5
LPHA 9.5
Kinase-related protein 9.5
GTP-binding protein Rab5 9.5
probable transposase 9.2
CT47 9.2
chymotrypsin-like protease 9.2
mast cell protease I 9.0
F379 8.9
TMEM114 8.9
MMSDH 8.9
cathepsin L-like protein 8.9
SERP2 8.9
trypsin I 8.9
skin tryptase 8.8
CTRB1 8.8
Carboxypeptidase A 8.7
chymotrypsin-like 8.7
C4a anaphylatoxin 8.7
CTRB2 8.7
AP3D1 8.7
PLC-III 8.7
more...
Disease
Subclinical diabetes 11.5
familial hypothyroidism 9.9
Peripancreatic necrosis 9.5
Pancreatic steatorrhea 9.2
Alcoholic liver damage 9.2
syphilid 8.3
Acute glaucoma 7.8
COND 7.8
Ehlers-Danlos syndrome type VII 7.6
Ligneous conjunctivitis 7.4
pancreatic insufficiency 7.4
EA4 7.2
MF4 6.9
Lederer 6.8
AD10 6.8
Clear cell chondrosarcoma 6.8
disaccharidase deficiency 6.7
blind loop syndrome 6.5
EPPS 6.3
Clostridium perfringens infection 6.3
steatorrhea 6.1
intestinal neoplasm 6.0
Takahara 6.0
Acinar cell carcinoma 6.0
Enzyme inhibition 5.8
ovarian mucinous cystadenocarcinoma 5.8
Shope papilloma 5.8
HSAN1 5.7
BDB 5.7
thrombopathy 5.6
Southeast Asian ovalocytosis 5.6
ocular hypertension 5.5
Glanzmann's thrombasthenia 5.5
Mevalonate kinase deficiency 5.3
EIC 5.2
chronic pancreatitis 5.2
ATE 5.2
Bernard-Soulier syndrome 5.2
Ectopic pancreas 5.1
SDS 5.0
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Symptom
Local swelling 7.8
autodigestion 6.4
change in stool 6.3
PAIN 5.4
Blanching 4.8
Spots 4.7
scaly skin 4.1
Halo 2.7
rundown 2.5
eds 2.5
Gastrointestinal symptoms 2.3
HSA 2.3
bitter taste 2.0
microbial colonization 1.5
hypoproteinemia 1.4
flushing 1.2
Wind 1.2
cachexia 1.0
skin damage 0.9
starvation 0.9
agitation 0.8
abdominal discomfort 0.8
diarrhea 0.6
tremor 0.5
heartburn 0.5
skin irritation 0.4
tense 0.4
flank pain 0.4
stigma 0.4
stridor 0.3
collapse 0.3
acidity 0.2
tachypnea 0.2
erythema 0.1
regurgitation 0.1
lethargy 0.0
paresis -0.0
hoarseness -0.0
abdominal pain -0.1
epigastric pain -0.2
more...
Drug
Proflavin 8.2
Benzenesulfonyl 8.2
Methacholine chloride 8.0
Z-Pro-Prolinal 7.8
Formycin 7.7
Methyltyrosine 7.7
Trazodon 7.7
Pronase 7.3
Papain 7.1
L-tyrosine 6.9
Tepoxalin 6.9
Tora 6.8
Trusopt 6.7
Protein hydrolysate 6.6
Aprotinin 6.5
Bromelain 6.4
DFP 6.4
Trifluoroethanol 6.2
Pancrease 6.1
Myotrophin 6.1
Secretin 6.0
Cardizem CD 5.9
Span 40 5.9
Sodium carbonate 5.8
Pancreatin 5.7
Ulinastatin 5.7
Sodium citrate 5.7
Sodium citrate 5.7
Tenecteplase 5.6
Loxiglumide 5.6
Dopexamine 5.5
Pyridoxal phosphate 5.4
Cremophor RH40 5.3
Ceredase 5.3
AMC 5.3
Gabexate mesilate 5.3
Timolol 5.1
Timolol maleate 5.1
Cobalamin 5.0
Deuterium oxide 5.0
more...
Enzyme
pyrrolooxygenase 11.5
chymotrypsin 11.5
Leu-proteinase 10.9
Scytalidium lignicolum acid proteinase 10.5
GluSGP 10.5
brachyurin 10.5
Sindbis virus core protein 9.9
EC 3.2.1.70 9.9
Streptomyces griseus protease B 9.8
pancreatic elastase 2 9.7
chymotrypsin C 9.6
coagulation factor XIa 9.4
glycolaldehyde dehydrogenase 9.2
ficin 9.0
alpha-lytic protease 8.9
duodenase 8.9
cucumisin 8.8
RVV-V 8.8
thermolysin 8.7
clostripain 8.7
proteinase yscD 8.7
endoproteinase Glu-C 8.6
trypsin 8.6
cathepsin G 8.6
phosphoamidase 8.5
subtilisin 8.5
endopeptidase I 8.5
carboxypeptidase A 8.5
hypodermin C 8.4
spermosin 8.3
elastase 8.3
carboxypeptidase S 8.3
papain 8.1
actinase E 8.0
thermitase 8.0
phytepsin 7.9
bromelain 7.9
lysyl endopeptidase 7.9
stratum corneum chymotryptic enzyme 7.8
endoproteinase Asp-N 7.7
more...
Compound
C24H40O4 11.5
C24H40O4 11.5
C24H40O4 11.5
C24H40O4 11.5
C24H40O4 11.5
C24H40O4 11.5
C24H40O4 11.5
C24H40O4 11.5
C24H40O4 11.5
C24H40O4 11.5
C24H40O4 11.5
dihydro-2(3H)-thiophenone 11.5
ethyl hentriacontanoate 11.5
C24H40O4 11.5
Ac-Tyr-OEt 10.5
C24H40O4 10.5
4-Methylumbelliferyl acetate 10.5
Tetraethylene glycol 10.5
C24H40O4 10.5
Salcomine 10.5
C10H8O2 9.9
3-bromopropanoic acid 9.9
7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid 9.9
Allochenodeoxycholic acid 9.9
Isoursodeoxycholic acid 9.5
isodeoxycholic acid 9.2
C5H6O4 9.2
C20H24N2O4 8.9
Cyclohexyl isocyanate 8.9
Orange IV 8.9
benzenecarboximidamide 8.7
2,1-benzisoxazole 8.7
trifluoroisoleucine 8.7
2-naphthyl acetate 8.6
TPCK 8.6
Chymostatin 8.6
N-Acetyl-L-tyrosine 8.5
alpha-Amyrin 8.5
Neoprontosil 8.5
N-acetylphenylalanine 8.5
more...