Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.21.1 (
chymotrypsin
)
10,938
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The single tryptophan residue of the black-eyed pea trypsin and
chymotrypsin
inhibitor was found to be sufficiently exposed to bind
N-methylnicotinamide
chloride and give rise to a characteristic charge-transfer absorption spectrum. At pH 7.0, ionic strength of 1M and 25 degrees C, an apparent association constant K = 3.19 +/- 0.07 M-1 and a molar extinction coefficient epsilon = 1240 +/- 18 M-1 cm-1 (at 350 nm) were obtained for the charge-transfer complex. The values of these parameters were also estimated for other wavelengths over the 330-420 nm range. The association constant showed a negligible dependence on the wavelength.
...
PMID:The state of the single tryptophyl of the black-eyed pea trypsin and chymotrypsin inhibitor by charge transfer with N-methylnicotinamide chloride. 623 79
