Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.16.2 (PCP)
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Human Gene/Protein
poly(A) polymerase alpha 13.0
PCP 13.0
Endopeptidase-2 11.0
growth arrest-specific 2 like 1 10.7
POU class 2 homeobox 1 10.7
selenophosphate synthase 10.7
ARHGEF19 10.7
HLA-DQ alpha chain 10.5
FHOD2 10.5
PCP2 10.4
LG72 10.2
PRDM15 10.2
H-REV107 10.2
endopeptidase-2 10.1
membrane-bound aminopeptidase P 10.0
prolylcarboxypeptidase 10.0
FBXL21 9.9
dishevelled-associated activator of morphogenesis 1 9.9
sigma receptor 9.8
dishevelled 2 9.7
PSL1 9.6
ITGBL1 9.5
FAPA 9.5
HSA10 9.3
SLC16A7 9.2
DAAM2 9.1
Diversin 9.1
IFN-omega 1 9.1
PCPH 9.1
NXN 9.0
M1 muscarinic cholinergic receptor 9.0
calmodulin 2 9.0
PSL2 9.0
PRCP 9.0
CEP192 9.0
myelin transcription factor 1 9.0
importin 13 9.0
Frizzled-related protein 1 8.8
PPP 8.7
glypican 4 8.7
PDE10A 8.7
NAV2 8.7
CELSR1 8.6
TCP 8.6
DVL3 8.5
histamine receptor H1 8.5
CG-2 8.5
DVL2 8.5
Visinin-like protein 1 8.5
WTIP 8.5
DAAM1 8.4
VANGL1 8.4
CTHRC1 8.3
PIAS2 8.3
DP-2 8.3
aminopeptidase P 8.2
PRDM5 8.2
Myelin transcription factor 1 8.2
HCP1 8.2
FMI 8.2
P76 8.2
PTK7 8.2
ROR2 8.2
DPP7 8.2
HDPR1 8.1
DVL1 8.1
WNT5B 8.1
RYK 8.1
DPP II 8.1
prostaglandin reductase 1 8.0
DACT2 8.0
p250 8.0
GPR48 8.0
mGlu2 8.0
PNP 8.0
DIAPH2 8.0
GPC4 8.0
UDPase 7.9
JIP1 7.8
FMNL1 7.8
more...
Disease
PCP intoxication 12.9
PCP dependence 12.5
PCP abuse 12.5
PCP 12.1
Deep fungal infection 10.5
schizophreniform psychosis 10.3
Chronic osteoarthritis 9.9
penicillosis 9.3
acute schizophrenic episode 9.3
Embryopathy 9.0
PPP 8.7
TCP 8.7
induced psychosis 8.4
Bipolar II disorder 8.3
FH3 8.0
cross-dependence 8.0
paranoid state 7.8
Cerebro-costo-mandibular syndrome 7.8
Brachydactyly 7.8
Insulin hypoglycemia 7.7
isosporiasis 7.6
FDD 7.5
alcoholic psychosis 7.5
catatonic stupor 7.5
HTX 7.3
HTX 7.3
schizophrenic psychosis 7.2
Robinow syndrome 7.1
EKC 6.9
catalepsy 6.9
blunted affect 6.8
perception disorder 6.7
Stereotypy 6.7
THC 6.7
Pneumocystis jiroveci pneumonia 6.7
stereotypies 6.6
cognitive deficit 6.6
Candida sepsis 6.3
Axis I diagnosis 6.3
polydrug use 6.2
BDB 6.2
schizophrenia 6.2
Craniopharyngioma 6.2
esophageal candidiasis 6.2
Factor V Leiden mutation 6.1
NPC 6.0
polysubstance abuse 5.9
acquired toxoplasmosis 5.8
physical dependence 5.8
psychosis 5.8
flashbacks 5.8
audiogenic seizure 5.7
bronchomalacia 5.7
Nystagmus 5.7
PHP 5.6
Kaposi's Sarcoma 5.6
impaired driving 5.5
Pneumocystis carinii infection 5.4
opportunistic infection 5.3
Gull 5.3
HCI 5.3
bacterial pneumonia 5.2
NPS 5.1
CMV retinitis 5.1
inferior myocardial infarction 5.1
HIV encephalopathy 5.1
LIP 5.1
wasting syndrome 5.1
derealization 5.1
lung consolidation 5.0
dental calculus 5.0
ACP 5.0
heroin abuse 4.9
craniopharyngioma 4.9
BPP 4.8
SCH 4.8
DNT 4.8
JIP 4.8
SCS 4.8
recurrent pneumonia 4.8
more...
Symptom
bloodshot eyes 8.7
Circling 8.0
sinus congestion 7.7
startle reaction 5.8
ataxia 5.4
bradypnea 5.4
Fluctuation 5.4
tonic seizure 5.3
incoordination 5.3
rundown 5.1
athetosis 5.0
non-productive cough 4.9
Spots 4.2
Respiratory symptoms 4.2
lightheadedness 4.0
productive cough 3.9
pleuritic chest pain 3.8
rales 3.7
orofacial pain 3.2
dry skin 3.1
muscle rigidity 3.0
hypertonia 2.8
cyanosis 2.8
tachypnea 2.7
spasticity 2.7
tonic-clonic seizure 2.7
apathy 2.6
seizures 2.6
hypothermia 2.6
agitation 2.5
despair 2.4
exertional dyspnea 2.3
memory loss 2.2
oliguria 2.2
lethargy 2.2
acute pain 2.1
Depressive symptoms 2.1
fever of unknown origin 2.0
cough 2.0
polydipsia 1.9
rhinorrhea 1.9
dyspnea 1.9
bradykinesia 1.8
pallor 1.7
shortness of breath 1.7
respiratory distress 1.6
analgesia 1.6
snoring 1.6
HSA 1.5
stigma 1.3
ophthalmoplegia 1.3
cerebellar ataxia 1.2
tremor 1.2
spasm 1.2
hemiplegia 1.1
myoclonus 1.0
anesthesia 0.8
numbness 0.7
hyperoxia 0.7
paresis 0.5
hemoptysis 0.5
anorexia 0.3
angina 0.3
vertigo 0.2
collapse 0.2
arthralgia 0.2
diarrhea 0.2
acidity 0.2
pain 0.1
dystonia 0.0
distraction -0.1
dizziness -0.2
low back pain -0.2
Ill -0.4
starvation -0.6
fatigue -0.6
erythema -0.6
functional recovery -0.7
headache -0.7
vomiting -0.9
more...
Drug
PCP 13.0
Lysine hydrochloride 11.5
Gavestinel 11.0
1-Aminoethyl 10.5
Blonanserin 10.3
Adenyl 10.0
Peridinin 9.2
Polycarbophil 9.0
Fenobam 9.0
Remoxipride 8.3
Zithromax 8.1
Eldepryl 8.0
Effexor 7.7
Bactrim 7.7
Ritanserin 7.5
Seroquel 7.5
Iloperidone 7.4
Trimethoprim-sulfamethoxazole 7.3
Magnesium chloride 7.1
Fluphenazine 7.1
Ketalar 7.0
Marimastat 6.9
Atovaquone 6.6
7-Nitroindazole 6.6
Ketalar 6.5
Trib 6.4
Atovaquone 6.2
9-THC 6.2
Kelp 6.0
Enoximone 6.0
Molsidomine 5.8
GVG 5.7
Quisqualate 5.6
SrCl2 5.5
Indapamide 5.5
CFT 5.4
C3H6 5.4
PZC 5.3
L-Ser 5.2
ARA-C 5.2
Ammonium chloride 5.2
Papaverine 5.2
Sulpiride 4.8
APD 4.8
Fondaparinux 4.7
Kainic acid 4.7
Guanidine 4.7
Flavin 4.6
Guanidine 4.6
Codeine 4.6
Indapamide 4.6
Flunitrazepam 4.6
Codeine 4.5
Cantor 4.5
Hydrochlorothiazide 4.4
Timolol 4.3
HCH 4.3
ddI 4.3
DFP 4.2
Glutamic acid 4.1
PCB 4.0
Atropine 3.9
Donepezil 3.9
CPM 3.8
MOF 3.8
Azithromycin 3.8
Urokinase 3.8
Apomorphine 3.8
Phenytoin 3.7
AZT 3.7
Carotenoid 3.5
DHT 3.5
OTC 3.5
THF 3.5
Ganciclovir 3.5
AZT 3.5
DHT 3.5
caffeine 3.5
Bupivacaine 3.4
PMPA 3.4
more...
Enzyme
xanthomonapepsin 13.0
PCP 13.0
pseudomonapepsin 13.0
EC 3.4.17.16 12.0
aminopeptidase W 11.2
GTP:adenosylcobinamide-phosphate guanylyltransferase 11.0
selenophosphate synthase 10.5
PcpB 9.8
CobC 9.7
aminopeptidase P 8.6
2-hydroxymuconic semialdehyde hydrolase 8.6
proline iminopeptidase 8.4
dTTPase 8.3
DAP II 8.3
procollagen C-proteinase 7.9
tubulin carboxypeptidase 7.7
dynein ATPase 7.6
alpha-aminoadipate reductase 7.6
dihydroneopterin aldolase 7.4
acyl carrier protein synthase 7.4
ribokinase 7.2
D-alanine:D-alanine ligase 7.0
prolyl endopeptidase 7.0
prolinase 6.9
prolidase 6.9
carboxyl proteinase 6.8
TSO 6.8
D-glucosyltransferase 6.7
2-keto-3-deoxy-6-phosphogluconate aldolase 6.6
glycerophosphodiester phosphodiesterase 6.6
dihydropteroate synthase 6.6
elongation factor (EF) 6.4
aminopeptidase A 6.3
PCE 6.3
DMT 6.1
BAL 5.7
pyroglutamate aminopeptidase 5.7
VIP1 5.6
NAO 5.6
TSR 5.5
proteinase A 5.5
carboxypeptidase G2 5.5
pyridoxal kinase 5.3
dipeptidyl peptidase IV 5.1
carboxypeptidase Y 5.0
proteinase A 5.0
lysyl-tRNA synthetase 5.0
meprin 4.9
alanine racemase 4.7
ferredoxin reductase 4.7
CPM 4.7
SCS 4.7
PDO 4.6
cathepsin H 4.5
histidine decarboxylase 4.5
matriptase 4.5
manganese peroxidase 4.4
cathepsin C 4.4
aryl hydrocarbon hydroxylase 4.4
PST 4.3
DNase II 4.3
lignin peroxidase 4.2
lactonase 4.2
matriptase 4.1
calcium pump 4.1
phosphoribulokinase 4.0
DOPA decarboxylase 4.0
PAL 4.0
aromatic L-amino acid decarboxylase 4.0
MDP 4.0
ADPase 3.9
prostate-specific membrane antigen 3.9
adrenodoxin reductase 3.8
carboxypeptidase B 3.8
adenylate kinase 3.7
MAP 3.7
PDH 3.6
phosphatidylinositol 4-kinase 3.6
type III procollagen 3.6
phosphoglycerate kinase 3.5
more...
Compound
1-benzyl-3-piperidinol 13.0
PCP 12.8
4-phenylcyclohexanol 12.5
Phencyclidine 12.4
Metazocine 12.0
2-chlorocyclohexanol 12.0
1-(1-(2-thienyl)cyclohexyl)piperidine 12.0
Chlornitrofen 12.0
2,3,4,5,6-pentachlorophenol 11.6
2,3,4,5,6-pentachlorophenol 11.5
Etoxadrol 11.5
6-chloro-1H-indole 11.5
bicyclo[3.1.0]hexan-3-one 11.5
Etoxadrol 11.5
Vibriobactin 11.5
3-methylpiperidine 11.1
3-methylpiperidine 11.1
C19H23N 11.0
1,2-dichlorocyclohexane 11.0
1-(1-phenylcyclohexyl)-4-piperidinol 11.0
bicyclo[3.1.0]hexan-3-one 11.0
C15H10O4 10.7
1,2-dichlorocyclohexane 10.5
2,4-dihydroxyphenylalanine 10.5
1,5-dibromopentane 10.5
DBNPA 10.5
4-phenyl-4-piperidinol 10.5
1-(1,2-diphenylethyl)piperidine 10.2
10-methyl-10H-phenothiazine 10.2
Cyclazocine 10.0
3,4,5-trichlorophenol 10.0
2-(3-methoxyphenyl)cyclohexanone 9.9
MBED 9.9
1,3,6,8-TCDD 9.9
PCPI 9.9
Histrionicotoxin 9.7
Bacitracin A 9.6
L-Lysine monohydrochloride 9.6
cyclohexanecarbonitrile 9.5
2,3,5,6-tetrachlorophenol 9.5
1-phenyl-1H-1,2,3-triazole 9.5
2-aminocyclohexanol 9.5
10,11-dihydro-5H-dibenzo[a,d]cycloheptene 9.5
2-aminocyclohexanol 9.5
3-methoxy-17-methylmorphinan 9.2
HOG 9.2
SOPP 9.2
o-benzyl-p-chlorophenol 9.2
1-benzylpiperidine 9.1
1-phenyl-1,2,3,4-tetrahydroisoquinoline 9.0
1-phenyl-1,2,3,4-tetrahydroisoquinoline 9.0
cyclohexylbenzene 9.0
cyclohexylbenzene 9.0
3-piperidinecarboxylic acid 8.8
4-phenyl-1H-1,2,3-triazole 8.7
Bremazocine 8.7
1-naphthalenesulfonic acid 8.7
1-naphthalenesulfonic acid 8.7
TCP 8.7
TCP 8.7
TCP 8.6
TCP 8.6
4-methylpiperidine 8.6
4-methylpiperidine 8.6
A47934 8.6
4-methylpiperidine 8.6
Kirromycin 8.5
MK801 8.5
Tetrachlorohydroquinone 8.5
1-benzylpiperazine 8.5
cyclooctane 8.4
Cartap 8.4
Mescaline 8.3
BPMC 8.3
1-benzylpiperazine 8.2
1,2-difluorobenzene 8.1
piperidine 8.1
piperidine 8.1
2-NP 8.1
Pentazocine 8.1
more...