Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.16.2 (
PCP
)
3,761
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Effect of sublethal concentrations (0.0083, 0.0055, 0.0041, 0.0033 and 0.0028 mg/l) of sodium penta-chlorophenate (Na-
PCP
) on the enzymes SDH,
PDH
and LDH in brain, liver and gills of Notopterus notopterus after 15 ad 30 days exposure were studied. SDH and
PDH
were inhibited, and LDH were stimulated significantly at most concentrations. However, changes were maximum (-68.3%, -73.4% and +197.7% for SDH,
PDH
and LDH, respectively) in brain after 30 days, and minimum (-1.3% and +2.4% for SDH and LDH, respectively) in gills and (-3.4% for
PDH
) brain after 15 days. Inhibition of SDH and
PDH
, and the stimulation of LDH activity indicate the development of anaerobic conditions at the cellular level in pollutant-stressed fish.
...
PMID:Effects of sodium pentachlorophenate on enzymes of energy metabolism in tissues of Notopterus notopterus. 708 Jan
