Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.16.2 (PCP)
 3,761 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Left ventricular filling pressure and cardiac output (C.O.) were studied at rest and during exercise in 145 patients with severe coronary artery disease, i.e. narrowing of at least one major coronary artery of greater than or equal to 50%. 95% of these patients had had a previous myocardial infarction. The most important findings are as follows: (1) Inappropriate C.O. at rest and during exercise indicates multiple vessel disease in most cases. (2) Marked increase of filling pressure during exercise indicates multiple vessel disease in most cases. (3) PCP during exercise is higher in patients with LAD disease (isolated or in combination with additional lesions), than in patients with RCA and/or left CX involvement.
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PMID:[Hemodynamics at rest and during exercise depending on severity and localization of coronary artery disease (author's transl)]. 120 31