Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.16.2 (PCP)
 3,761 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Delinquent males committed to a training school were interviewed to determine the extent and the effects of phencyclidine use. Nine of 109 (8%) drug using subjects knowingly had used phencyclidine in the past. These nine subjects were multiple drug abusers of other substances and had started taking drugs at an average age of 9.38 years which was significantly younger than non PCP users. Six of the nine PCP users had committed proven offenses against persons and in four cases violent actions were directly attributed to PCP use. Suicide attempts were made by five (55%) of the PCP users which was significantly more frequent than suicide attempts made by non PCP users.
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PMID:Phencyclidine use in delinquent males committed to a training school. 52 14

Drug abuse patterns are examined for 326,611 males and females who abused drugs and were treated at a hospital emergency room or died. The data reveal a marked percentage difference between male and female mentions of heroin, PCP, and diazepam. A significantly larger proportion of females than males indicated their motivation for drug abuse to be a suicide attempt or gesture. Diazepam, alcohol-in-combination, and aspirin are the most frequently mentioned drugs by those whose motivation is suicidal. However, the percentage difference between males and females for these three drugs is less than 6%. The data were collected during the years 1976-1979.
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PMID:Sex differences in substance abuse: 1976-1979. 682 67

This study presents self-report cross-sectional and longitudinal data on associations between drug use, suicide ideation, and attempts in a multiethnic sample of seventh- and eighth-grade male adolescents attending school in the greater Miami, Florida, area. African Americans had the highest prevalence of 6-month ideation (20.5%), and Haitians had the highest attempts (11.4%). For the total sample, tranquilizers had the highest odds ratio for ideation (3.4), and PCP for attempts (6.2). Psychoactive drug-use was consistently related to attempts among Hispanics, white non-Hispanics, and African Americans. Acculturation strains interacted with cocaine and crack to predict suicide attempts among Hispanic respondents.
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PMID:The relationship of drug use to suicide ideation and attempts among African American, Hispanic, and white non-Hispanic male adolescents. 834 10