Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.16.2 (PCP)
 3,761 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Presentations at the Fifth Annual Conference on HIV/AIDS Research in Winnipeg (Canada) considered the level of viral load and CD4+ counts that can be used to guide therapeutic decisions. Discussions centered on the dangers of relying too heavily on any one measurement of an individual's viral load, and other topics, such as what happens when trial dropouts all have low CD4+ counts, when to worry about patients with 650 T cells, and why multidrug therapy is the least inadequate option. Among the many other topics discussed are 1) Francis Plummer's work in tracking 1500 commercial sex workers over 10 years, indicating the resistance to HIV infection of some Kenyan women; 2) use of mail-in blood spots for early HIV diagnosis; 3) development of Thai vaccine efficacy trials starting within 2 years; and 4) problems in statistical analysis of study results. The article highlights the prediction of CMV progression, the prevalence of abnormal Pap smears in HIV-positive women, the isolation of a distinct mycobacterium (Mycobacterium genavense) that is being spread through Canada, soaring HIV risk during college spring break, rectal gonorrhea as a HIV risk factor, weight loss as a predictor of PCP, and identification of a new HIV-1 subtype in Ontario which was previously common only in several Central African countries.
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PMID:Winnipeg conference. What do the numbers mean? 1136 23

Statistics show that the prevalence of crack cocaine use and embalming fluid and phencyclidine (PCP)-laced cigarettes or marijuana sticks, commonly referred to on the street as "fry" or "wet" is a problem; however, the relationship between these substances of abuse and concurrent polydrug use is unknown. In the present study, a cross-sectional survey was conducted among 426 African-American crack users in Houston, Texas, to investigate the difference between those who concurrently reported lifetime (defined as at least one usage of fry in life) fry use and those who stated they never used fry. The data were analyzed using chi-square and logistic regression analyses. Fry users were significantly more likely than non-users to not have a casual sex partner (92% users vs. 84% non-users, p < or = 0.05) and were more likely to have been diagnosed with gonorrhea in the past 12 months (9% users vs. 2% non-users, p < or = 0.05). In addition fry users had significantly higher odds of currently trading sex for drugs (OR = 2.30, p < or = 0.05), marijuana use (OR = 12.11, p < or = 0.05), and codeine (syrup) use (OR = 8.10, p < or = 0.05). These findings are important in determining the "cultural novelties" relative to crack and fry use among younger African Americans.
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PMID:The use of fry (embalming fluid and PCP-laced cigarettes or marijuana sticks) among crack cocaine smokers. 1915 45