Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.16.2 (PCP)
 3,761 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Hypertrophic osteoarthropathy (HOA) is a systemic disorder primarily affecting the bones, joints, and soft tissues and developing in association with another disease process. Acute pyogenic pulmonary processes (empyema, lung abscess) are occasionally accompanied by transient HOA, but reversible HOA has not previously been reported in the setting of PCP in AIDS.
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PMID:Hypertrophic osteoarthropathy associated with Pneumocystis carinii pneumonia in AIDS. 280 56

The indication for knee injection depends on the drugs to be used and the illness to be treated. These are lot of degenerative and inflammatory joint pains which demand for monarticular treatment by corticosteroid crystal suspension, local anaesthetica, non-steroidal antiinflammatory substances or drugs for chemical synovectomy in PCP. The technique is quite easy as for the big volume and the broad entrance of the articular space when the knee is flexed. The demand of hygienic circumstances must content a handling which prevents infection by quite simple methods by local antiseptics for the skin and one-way instruments. With the seldom exception of haemarthros and osteochondral necrosis infection is the utmost danger of knee injection. The putride arthritis should be managed by early synovectomia and movement trauma in order to limit infection and prevent ankylosis. Nevertheless, in case of empyema half of the joints will not regain their pre-existent movement and nearly a quarter loses their natural function.
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PMID:[Indications, technic and dangers of intra-articular injection treatment of the knee]. 342 55