Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.15.1 (
ACE
)
18,300
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ACE
10.8
CPN4
10.8
angiotensin I-converting enzyme
10.8
THUMP domain containing 1
10.8
voltage-dependent L-type calcium channel alpha 1C subunit
10.8
ANG-3
10.8
kallikrein-related peptidase 9
10.8
Prostaglandin F2 receptor negative regulator
10.8
DCP
10.6
PDH
10.6
cytochrome b-245 beta polypeptide
9.8
b2 microglobulin
9.8
ANG-5
9.8
sperm autoantigenic protein 17
9.8
kininase I
9.3
Angiotensin-converting enzyme
9.3
succinyl-CoA:3-ketoacid-CoA transferase
9.2
SLC25A44
9.2
C7orf31
9.2
GALNTL6
9.2
threonine-tRNA ligase
9.2
AGTR1
9.0
ACTN3
8.9
membrane-bound aminopeptidase P
8.8
MLCK2
8.8
EPRAP
8.8
RENBP
8.8
activin A receptor, type IIB
8.8
cartilage intermediate layer protein 2
8.8
RENIN
8.6
PDHK2
8.6
angiotensin receptor
8.5
PDP2
8.5
ARB1
8.4
TTC39C
8.4
MRPL38
8.4
CEP68
8.4
PLEKHA2
8.4
pyruvate dehydrogenase alpha subunit
8.4
MRPL44
8.4
GHN
8.4
ETNK2
8.4
carboxypeptidase N
8.4
ACE2
8.4
ACEH
8.3
T2R1
8.3
ANG1
8.3
AGT
8.3
ECE2
8.3
MRPL11
8.2
collectrin
8.2
MMSDH
8.2
IQCK
8.2
PGBD1
8.2
RPH3A
8.2
MYG
8.2
acylase III
8.2
angiotensin II receptor
8.2
AGTR2
8.1
DCP1
8.1
alpha-actinin 3
8.1
ARB
8.0
angiotensin I converting enzyme
8.0
Angiotensin I converting enzyme
8.0
RNF25
8.0
PLEKHB1
8.0
ALG10
8.0
PP36
8.0
ATP8B3
8.0
THEM4
8.0
adducin 1
8.0
CGNL1
8.0
HSPA14
8.0
SSRC
8.0
UNC13B
8.0
carboxypeptidase O
8.0
zinc metallopeptidase
7.9
Angiotensin II receptor
7.9
aminopeptidase P
7.9
FCER1B
7.9
more...
Disease
bradykinin hypertension
10.8
Drug-induced malabsorption
10.8
Neonatal anuria
10.8
Instantaneous clearance
10.8
Drug-induced bullous pemphigoid
9.8
Small bowel angioedema
9.2
Residual proteinuria
9.2
Drug-induced urticaria
8.8
High altitude polycythemia
8.8
Splenic sarcoidosis
8.8
Drug-induced sexual dysfunction
8.8
Acute transmural myocardial infarction
8.8
Alimentary obesity
8.4
Post MI
8.4
Sarcoid uveitis
8.4
Acute left ventricular failure
8.3
Serum potassium increased
8.2
Potassium retention
8.2
Scleroderma renal crisis
8.2
Lymphocytic alveolitis
8.1
Bladder hypertrophy
8.0
Psychogenic cough
8.0
Renal magnesium wasting
8.0
Drug-induced hyperkalemia
7.8
High output heart failure
7.8
Lupus myocarditis
7.8
uncomplicated hypertension
7.7
Limited cutaneous systemic sclerosis
7.6
Acute nephritis
7.6
Nephroangiosclerosis
7.6
AKE
7.5
Intraoperative hypertension
7.4
IDDM10
7.3
Heerfordt's syndrome
7.2
Nephrotic range proteinuria
7.2
high renin hypertension
7.2
Erosive adenomatosis of the nipple
7.2
Ocular sarcoidosis
7.2
reninoma
7.1
PLAT
7.1
Unilateral renal artery stenosis
7.1
PDH deficiency
7.1
Chronic heart failure
7.0
Non-sustained ventricular tachycardia
7.0
Diastolic heart failure
7.0
renin-dependent hypertension
6.9
Systolic heart failure
6.9
Cytokine storm
6.9
Chronic iron overload
6.9
Decompensated heart failure
6.9
juxtaglomerular cell hyperplasia
6.9
Late pregnancy
6.9
microalbuminuria
6.7
Tracheopathia osteoplastica
6.7
renal scleroderma
6.7
Stable angina
6.7
IDDM8
6.7
Goldblatt
6.6
Age-associated memory impairment
6.6
Secondary hyperaldosteronism
6.6
Insulin allergy
6.5
Partington syndrome
6.5
Necrotizing sarcoid granulomatosis
6.5
Coombs positive hemolytic anemia
6.5
Schindler disease
6.5
systolic hypertension
6.5
hypercupremia
6.5
Hypertensive retinopathy
6.5
Hypertensive retinopathy
6.5
Renal scarring
6.4
Subcutaneous sarcoidosis
6.4
Radiation Syndrome
6.4
hypertensive heart disease
6.4
hyporeninemic hypoaldosteronism
6.4
Neurosarcoidosis
6.4
Hypersensitivity syndrome
6.4
HPA1
6.4
renal artery stenosis
6.3
Renovascular hypertension
6.3
Proteinuria
6.3
more...
Symptom
Drug-induced cough
10.8
Persistent dry cough
9.5
Gastrointestinal discomfort
7.2
Local swelling
7.1
axillary pain
6.6
postnasal drip
6.1
rales
5.8
Acute dyspnea
5.8
renal pain
5.7
Todd's paralysis
5.4
non-productive cough
5.2
stomach cramps
5.2
loss of taste
5.0
localized edema
5.0
pedal edema
5.0
cardiovascular impairment
5.0
abnormal reflex
5.0
PAIN
4.7
persistent cough
4.5
cough
4.5
Flare
4.3
chronic cough
4.2
growing pains
4.2
oliguria
4.1
Exercise intolerance
3.9
hematocolpos
3.8
angina
3.8
polyuria
3.4
physical exhaustion
3.4
dizziness
3.4
frequent urination
3.3
Neurologic symptoms
3.2
polydipsia
3.2
adipsia
3.2
exertional angina
3.2
Stiffness
3.1
atypical chest pain
3.0
Cushingoid
3.0
leg edema
3.0
Cushingoid
3.0
shortness of breath
2.9
disturbed balance
2.9
orthopnea
2.9
CSR
2.9
ACHE
2.9
Multimorbidity
2.9
Decreased activity
2.7
dyspnea
2.7
ketonuria
2.7
lassitude
2.6
hypoproteinemia
2.6
prostatism
2.6
pleuritic chest pain
2.6
asthenia
2.6
flushing
2.5
anosmia
2.5
loin pain
2.4
respiratory distress
2.3
hepatosplenomegaly
2.2
prostration
2.2
HSA
2.2
productive cough
2.2
mastalgia
2.2
night sweats
2.1
renal colic
2.1
hypertonia
2.1
livedo
2.0
loss of balance
1.9
muscle cramps
1.9
chest pain
1.9
Halo
1.9
blackout
1.9
exertional dyspnea
1.8
syncope
1.8
stomach pain
1.8
Catch
1.8
lightheadedness
1.8
splenomegaly
1.7
fever of unknown origin
1.7
myalgia
1.7
more...
Drug
Delapril hydrochloride
10.8
Disomotide
10.8
Libenzapril
10.8
Mirfentanil hydrochloride
10.8
Temocapril hydrochloride
10.8
Livact
10.2
Ecadotril
10.0
Cynt
9.8
Tartaric Acid
9.8
Ceronapril
9.8
Quinaprilat
9.5
Enalaprilat
9.4
Enalaprilat
9.4
Fosinopril sodium
9.4
Alacepril
9.4
Cilazapril
9.4
Benazeprilat
9.2
Pentopril
9.2
Fosinoprilat
9.2
INSPRA
9.2
Zosuquidar trihydrochloride
9.2
Eltrombopag olamine
9.2
Alosetron hydrochloride
9.2
Saralasin acetate
9.2
Omapatrilat
9.2
Ramipril
9.1
Volociximab
9.0
Accupro
9.0
Zofenopril calcium
9.0
Perindopril
8.9
Trandolapril
8.8
Canfosfamide hydrochloride
8.8
Accupril
8.8
Casopitant mesylate
8.8
Pazopanib hydrochloride
8.8
Dronedarone hydrochloride
8.8
Enalapril maleate
8.7
Lotrel
8.7
Captopril
8.6
3-Chlorophenol
8.4
Conivaptan hydrochloride
8.4
Concor
8.4
Atacand
8.4
Enzastaurin hydrochloride
8.4
Imidapril hydrochloride
8.4
Benazepril hydrochloride
8.3
Becatecarin
8.2
Teveten
8.2
Gantrisin
8.2
Guanadrel
8.2
Aliskiren
8.0
Monopril
8.0
Dibasic calcium phosphate
8.0
Dichlorophenamide
8.0
Atacand
8.0
Tandutinib
8.0
Apstatin
8.0
Apaziquone
8.0
Mecasermin rinfabate
8.0
Gantrisin
8.0
Aliskiren fumarate
7.8
Losartan potassium
7.7
2-Chlorophenol
7.7
Manidipine hydrochloride
7.6
Teveten
7.6
Sulotroban
7.4
Atomoxetine hydrochloride
7.4
Ziprasidone hydrochloride
7.4
Vernakalant hydrochloride
7.3
Toborinone
7.3
Lercanidipine
7.2
Valsartan
7.1
Fingolimod hydrochloride
7.1
Fosamprenavir calcium
7.1
Z-Pro-Prolinal
7.1
Atazanavir sulfate
7.0
Camostat mesilate
7.0
Norvasc
7.0
Inspra
7.0
Alvocidib
7.0
more...
Enzyme
ACE
10.8
PDH
10.7
dipeptidyl carboxyhydrolase
10.2
aminopeptidase W
9.6
oligopeptidase A
9.3
peptide hormone inactivating endopeptidase
9.2
carboxypeptidase Taq
8.8
dipeptidyl-dipeptidase
8.8
CPN
8.4
aminopeptidase P
8.2
D-2-haloacid dehalogenase
8.2
AGT
8.1
BCKDH
7.8
thimet oligopeptidase
7.6
3beta-HSDH
7.5
arogenate dehydrogenase
7.5
neurolysin
7.4
fRMsr
7.3
angiotensin-converting enzyme 2
7.3
renin
7.2
chymase
6.9
2,4-dichlorophenol hydroxylase
6.9
carboxylate reductase
6.6
XMT
6.5
bacillolysin
6.4
CD10
6.3
MDH
6.2
aminopeptidase B
6.2
prephenate dehydrogenase
6.2
kallikrein
6.1
MDH
6.1
15-hydroxyprostaglandin dehydrogenase
6.1
endothelin-converting enzyme
6.0
aminopeptidase A
6.0
pyruvate dehydrogenase
5.9
pyruvate dehydrogenase
5.9
serum carnosinase
5.9
prephenate dehydrogenase
5.9
XMT
5.9
2-oxoglutarate decarboxylase
5.9
methylmalonate-semialdehyde dehydrogenase
5.8
tripeptidase
5.7
tissue kallikrein
5.7
pyruvate dehydrogenase
5.7
carboxypeptidase B
5.7
thermolysin
5.6
enkephalinase B
5.6
prolyl endopeptidase
5.5
dipeptidyl peptidase IV
5.5
aspartyl aminopeptidase
5.5
PDK1
5.5
chloromuconate cycloisomerase
5.4
carnosinase
5.4
bleomycin hydrolase
5.4
carboxypeptidase A
5.3
carboxypeptidase E
5.3
pyruvate dehydrogenase phosphatase
5.3
pyroglutamyl peptidase II
5.2
PRA
5.2
actinidin
5.2
maleylacetate reductase
5.2
glutamine transaminase K
5.1
lipoate acetyltransferase
5.1
electron transfer flavoprotein dehydrogenase
5.0
caricain
5.0
CPM
5.0
SCP
4.9
nicotianamine synthase
4.9
GP-I
4.9
CD13
4.8
PepX
4.8
cathepsin V
4.8
cathepsin C
4.8
C1 esterase
4.7
glucose-6-phosphate dehydrogenase
4.7
serralysin
4.6
MDP
4.6
glycogen synthase phosphatase
4.6
LipB
4.5
octopine dehydrogenase
4.5
more...
Compound
C13H15NO6
10.8
C15H10N2O5
10.8
C12H13NO6
10.8
C12H17NO5
10.8
C13H15NO6
10.8
C12H17NO5
10.8
C13H15NO6
10.8
C12H17NO5
10.8
C15H10N2O5
10.8
C13H15NO6
10.8
C12H13NO6
10.8
L-Aspartyl-L-phenylalanine
10.8
C15H10N2O5
10.8
C13H15NO6
10.8
C12H17NO5
10.8
C12H17NO5
10.8
C12H13NO6
10.8
C15H10N2O5
10.8
C13H15NO6
10.8
Verticine
10.8
C12H17NO5
10.8
C12H13NO6
10.8
C13H15NO6
10.8
C13H15NO6
10.8
C13H15NO6
10.8
C12H17NO5
10.8
C12H17NO5
10.8
C12H17NO5
10.8
C13H15NO6
10.8
C15H10N2O5
10.8
C13H15NO6
10.8
C13H15NO6
10.8
C12H17NO5
10.8
C13H15NO6
10.8
C12H13NO6
10.8
C12H13NO6
10.8
C12H13NO6
10.8
DCP
10.7
C13H15NO6
10.2
C13H15NO6
10.2
PDH
10.2
DCP
10.1
Teprotide
9.9
C13H15NO6
9.8
C15H10N2O5
9.8
Neoastilbin
9.8
C13H15NO6
9.8
1,3-dichloro-2-propanol
9.7
Benazepril
9.5
3-pyridinesulfonamide
9.4
C13H15NO6
9.4
Enalaprilat
9.4
Fosinopril
9.3
2-chloroacrylic acid
9.2
1,1-Dichloropropene
9.2
C25H45NO
9.2
C15H10N2O5
9.2
C15H10N2O5
9.2
C12H15NO5
9.2
(+)-Syringaresinol
9.2
Perindopril erbumine
9.2
2,5-DCP
9.1
Perindopril
9.1
Quinapril
9.0
Enalapril
8.9
2,4-dichlorophenol
8.9
2,3-dichloro-1-propene
8.8
Quinapril hydrochloride
8.8
LPR
8.5
3,5-dichlorophenol
8.5
Angiotensin I
8.5
Moexipril
8.4
3-isoquinolinecarboxylic acid
8.4
C10H7NO2
8.4
C10H7NO2
8.4
3,4-dichlorophenol
8.3
Ebelactone B
8.3
Phenylacetylglutamine
8.3
2,3-dichlorophenol
8.3
1,2-dichloropropane
8.3
more...