Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.15.1 (
ACE
)
18,300
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ACE
8555
renin
3111
angiotensin II
2246
Ang II
1432
DCP
1221
Sep
1168
bradykinin
1088
Angiotensin-converting enzyme
1015
angiotensin I-converting enzyme
911
angiotensin receptor
815
insulin
738
calcium channel
728
PDH
656
Mol
517
angiotensin II receptor
514
AT1
513
angiotensinogen
410
neutral endopeptidase
342
albumin
341
collagen
312
more...
Disease
hypertension
4185
heart failure
1848
diabetes
1466
renal disease
828
myocardial infarction
828
congestive heart failure
793
proteinuria
659
essential hypertension
619
stroke
581
cardiovascular disease
575
ATM
514
diabetic nephropathy
477
atherosclerosis
454
sarcoidosis
441
renal failure
433
ventricular hypertrophy
419
coronary artery disease
389
type 2 diabetes
361
cancer
339
myocardial ischemia
300
more...
Symptom
cough
308
angina
166
pain
103
dyspnea
103
headache
102
anesthesia
83
diarrhea
65
fatigue
59
dizziness
57
respiratory distress
55
weakness
45
overweight
40
chest pain
38
vomiting
37
abdominal pain
33
nausea
32
seizures
29
shortness of breath
23
flushing
21
chronic cough
21
more...
Drug
Cardiovasc
553
Captopril
521
Angiotensin II
300
Ramipril
133
Perindopril
93
lysine
62
Enalaprilat
60
Enalaprilat
59
nitroglycerin
53
Cilazapril
52
Dial
51
Monit
49
Dermatol
44
NADH
44
Aliskiren
39
Valsartan
38
ROS
35
CSF
34
vitamin E
34
MAP
32
more...
Enzyme
ACE
18300
renin
3111
PDH
656
CD10
451
kallikrein
241
pyruvate dehydrogenase
164
trypsin
136
ERK
134
superoxide dismutase
128
pyruvate dehydrogenase
123
pyruvate dehydrogenase
123
AGT
120
glucose-6-phosphate dehydrogenase
113
catalase
101
lactate dehydrogenase
96
chymase
93
angiotensin-converting enzyme 2
93
CPN
87
pepsin
78
NO synthase
78
more...
Compound
acetate
8647
Clin
1466
Dec
1408
calcium
1271
DCP
1153
DCP
1153
aldosterone
1102
sodium
959
water
955
Angiotensin II
784
glucose
719
PDH
658
creatinine
588
Ang II
560
oxygen
527
Cardiol
508
salt
486
nitric oxide
425
potassium
417
2,4-dichlorophenol
401
more...