Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.15.1 (ACE)
18,300 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein ACE 8555 renin 3111 angiotensin II 2246 Ang II 1432 DCP 1221 Sep 1168 bradykinin 1088 Angiotensin-converting enzyme 1015 angiotensin I-converting enzyme 911 angiotensin receptor 815 insulin 738 calcium channel 728 PDH 656 Mol 517 angiotensin II receptor 514 AT1 513 angiotensinogen 410 neutral endopeptidase 342 albumin 341 collagen 312 ACE2 284 SARS 248 Renin 226 kallikrein 211 angiotensin-converting enzyme 2 190 peptidase 173 chronic renal failure 165 Mal 161 ARB 154 substance P 149 AT1R 149 nitric oxide synthase 144 AT2 144 ANG 142 vasopressin 130 cytokine 130 pyruvate dehydrogenase 128 hemoglobin 127 AGT 120 mineralocorticoid receptor 119 atrial natriuretic peptide 115 TCP 112 Pol 110 endothelin-1 109 TNF 109 glucose-6-phosphate dehydrogenase 108 aminopeptidase 104 ATP 100 HDL 99 superoxide dismutase 97 GSH 96 chymase 94 natriuretic peptide 93 GFR 90 DBP 87 lactate dehydrogenase 86 LDH 86 SBP 84 catalase 82 NMR 81 C18 81 vascular endothelium 77 She 77 gut 76 MTHFR 76 bradykinin B2 receptor 76 angiotensin I converting enzyme 75 plasminogen activator inhibitor-1 75 vascular endothelial growth factor 73 eNOS 73 alanyl 73 membrane-bound 71 alkaline phosphatase 71 ATPase 68 SDS 68 NEP 67 casein 67 cyclooxygenase 66 APOE 66 Met 64 MRI 64 glycoprotein 63 tumor necrosis factor 63 lysozyme 62 C-reactive protein 61 urinary kallikrein 61 IL-6 61 kininase I 60 AGTR1 58 serum albumin 57 fibrinogen 57 PLA 57 atrial natriuretic factor 55 AII 54 NIDDM 54 acetylcholinesterase 53 glucosidase 53 apolipoprotein E 53 phosphodiesterase 52 metalloendopeptidase 52 ACTN3 52 fibronectin 51 beta 1 51 TGF-beta 51 amylase 50 endothelial nitric oxide synthase 48 NOS3 48 Gen 47 pyruvate dehydrogenase complex 47 thrombin 47 erythropoietin 47 glutathione peroxidase 46 brush border 45 Pseudomonas 45 polypeptide 45 reductase 45 HMG-CoA reductase 45 chymotrypsin 45 SDH 44 ANP 43 CYP11B2 43 proximal tubule 42 ESI 42 ET-1 41 endothelin receptor 41 lipopolysaccharide 40 mast cell 40 ANOVA 40 NADPH 40 IgA 40 plasminogen activator inhibitor 39 CD4 39 NADH 39 TOF 39 TNF-alpha 38 carboxypeptidase N 38 aldosterone synthase 37 NAD 37 prothrombin 36 IDDM 36 CRP 36 SOD 36 Angiotensin II receptor 36 interleukin-6 36 peroxidase 35 aminopeptidase P 35 ROS 35 PRA 35 BNP 34 MDH 34 AMP 34 ASA 34 cathepsin D 34 DPP 33 creatine kinase 33 caspase-3 33 myosin 33 CD8 33 metalloprotease 33 fused 32 more...

Disease hypertension 4185 heart failure 1848 diabetes 1466 renal disease 828 myocardial infarction 828 congestive heart failure 793 proteinuria 659 essential hypertension 619 stroke 581 cardiovascular disease 575 ATM 514 diabetic nephropathy 477 atherosclerosis 454 sarcoidosis 441 renal failure 433 ventricular hypertrophy 419 coronary artery disease 389 type 2 diabetes 361 cancer 339 myocardial ischemia 300 SARS 290 obesity 277 acute myocardial infarction 266 chronic renal failure 260 microalbuminuria 245 coronary heart disease 232 ischemia 229 tumor 201 Alzheimer's disease 182 renal insufficiency 179 glomerulosclerosis 172 cardiomyopathy 143 metabolic syndrome 141 type 1 diabetes 132 depression 130 renal artery stenosis 129 hyperglycemia 128 dementia 121 heart disease 120 dilated cardiomyopathy 118 anemia 117 TCP 112 vascular disease 109 renal impairment 107 hypercholesterolemia 104 hyperlipidemia 103 SEM 101 GSH 97 acute renal failure 96 plaque 95 asthma 95 dyslipidemia 94 NAME 89 nephrotic syndrome 88 pneumonia 87 systolic hypertension 87 lymphadenopathy 82 retinopathy 76 pulmonary hypertension 76 cognitive impairment 75 Proteinuria 74 SDS 68 hyperinsulinemia 66 cold 64 glomerulonephritis 63 IgA nephropathy 62 chronic obstructive pulmonary disease 59 cirrhosis 57 PSS 57 glucose intolerance 57 sepsis 55 aldosteronism 55 HIV 54 unstable angina 52 sepsis 51 myocarditis 51 pulmonary edema 50 scleroderma 50 diabetic retinopathy 49 hepatocellular carcinoma 47 pulmonary fibrosis 47 Parkinson's disease 47 ventricular dilatation 47 preeclampsia 46 neuropathy 46 carcinoma 45 left ventricular failure 43 systemic lupus erythematosus 43 rash 43 malignant hypertension 42 migraine 42 Chronic heart failure 41 hypertensive heart disease 41 tuberculosis 40 ventricular fibrillation 40 hypercalcemia 40 hypoglycemia 39 rheumatoid arthritis 39 chronic renal insufficiency 38 uveitis 38 vasculitis 38 Goldblatt 38 breast cancer 37 uncomplicated hypertension 36 dehydration 36 nephrosclerosis 35 lung cancer 33 influenza 33 Hereditary angioedema 33 West 33 virus infection 33 arteriosclerosis 33 peripheral vascular disease 33 nephritis 33 osteoporosis 32 glomerulopathy 32 renal hypertension 32 uterus 31 Endothelial dysfunction 31 erectile dysfunction 30 idiopathic dilated cardiomyopathy 30 liver disease 30 adult respiratory distress syndrome 29 autoimmune disease 29 cardiovascular risk factor 29 carcinogenesis 29 diabetic cardiomyopathy 29 mitral regurgitation 29 respiratory failure 28 lymphoma 28 hyperthyroidism 26 lung disease 26 hypothyroidism 25 liver fibrosis 25 chronic glomerulonephritis 25 aortic stenosis 25 epididymis 25 azotemia 25 Brown 24 diastolic hypertension 24 secondary hypertension 24 genetic hypertension 24 infectious diseases 24 anaphylaxis 24 sympathomimetic 24 anuria 24 polycystic kidney 23 Evans 23 Duchenne muscular dystrophy 23 valvular heart disease 23 arthritis 23 chronic disease 23 aggression 23 thrombocytopenia 23 tumor growth 22 ICD 22 lupus 22 primary biliary cirrhosis 22 Conn 22 hypertrophic cardiomyopathy 22 more...

Symptom cough 308 angina 166 pain 103 dyspnea 103 headache 102 anesthesia 83 diarrhea 65 fatigue 59 dizziness 57 respiratory distress 55 weakness 45 overweight 40 chest pain 38 vomiting 37 abdominal pain 33 nausea 32 seizures 29 shortness of breath 23 flushing 21 chronic cough 21 starvation 20 rales 20 splenomegaly 19 polyuria 19 syncope 19 oliguria 18 erythema 18 Welt 16 exhaustion 15 collapse 15 thinning 15 analgesia 14 anorexia 14 discomfort 14 constipation 14 discomfort 14 arthralgia 12 polydipsia 12 acidity 12 hepatosplenomegaly 12 myalgia 12 functional recovery 11 agitation 11 sleepiness 11 regurgitation 10 postnasal drip 10 vertigo 10 asthenia 9 ataxia 9 hepatomegaly 9 Ill 8 HSA 8 nausea and vomiting 8 tremor 8 hyperoxia 8 hypercapnia 8 hypothermia 8 persistent cough 8 spasm 8 exertional dyspnea 7 cachexia 7 loss of taste 7 paresthesia 6 non-productive cough 6 hemoptysis 6 Stiffness 5 anosmia 5 wheezing 5 ENT 5 apathy 5 acute stress 4 dystonia 4 fever of unknown origin 4 spasticity 4 Wind 4 numbness 4 exertional angina 4 hypotonia 4 acute abdomen 4 lethargy 4 epigastric pain 4 pedal edema 4 hypoproteinemia 4 hoarseness 4 paresis 4 dysarthria 3 productive cough 3 acute abdominal pain 3 sore throat 3 back pain 3 atypical chest pain 3 night sweats 3 hypocapnia 3 chills 3 Persistent dry cough 3 CSR 3 leg edema 3 stridor 3 hemiplegia 3 hypertonia 3 localized edema 2 bitter taste 2 dental pain 2 enuresis 2 blurred vision 2 ketonuria 2 flank pain 2 tingling 2 insomnia 2 stigma 2 renal pain 2 livedo 2 distraction 2 cardiovascular impairment 2 neck pain 2 Flare 2 orthopnea 2 renal colic 2 snoring 2 muscle stiffness 2 pleuritic chest pain 2 twitching 2 chronic constipation 2 Decreased activity 2 muscle cramps 2 pallor 2 cyanosis 2 wrist pain 1 Cushingoid 1 despair 1 tonic-clonic seizure 1 loss of balance 1 dysuria 1 tinnitus 1 Fluctuation 1 tachypnea 1 facial pain 1 memory loss 1 knee pain 1 disturbed balance 1 Halo 1 loin pain 1 consciousness disturbance 1 blackout 1 stomach cramps 1 prostatism 1 PAIN 1 dry eye 1 abnormal reflex 1 masculinization 1 acute pain 1 asynergy 1 Cushingoid 1 incoordination 1 lightheadedness 1 nasal congestion 1 growing pains 1 limb pain 1 Drug-induced cough 1 Todd's paralysis 1 more...

Drug Cardiovasc 553 Captopril 521 Angiotensin II 300 Ramipril 133 Perindopril 93 lysine 62 Enalaprilat 60 Enalaprilat 59 nitroglycerin 53 Cilazapril 52 Dial 51 Monit 49 NADH 44 Dermatol 44 Aliskiren 39 Valsartan 38 ROS 35 vitamin E 34 CSF 34 MAP 32 Trandolapril 31 Indomethacin 29 Asn 29 Digitalis 28 citric acid 25 Omapatrilat 24 ascorbate 24 Nephron 22 Hydrochlorothiazide 19 PTH 18 TiO2 17 Albumin 17 CTX 16 ETA 16 Atenolol 14 MRC 13 Nephron 13 Fraction 13 Enalapril maleate 13 PCP 12 Asthma 12 lactose 11 niacin 11 THF 11 L-tyrosine 11 Triclosan 10 Felodipine 10 Alacepril 10 ENT 10 Ethanol 10 Phosphoramidon 9 Leaf 9 ADM 9 caffeine 9 Aprotinin 9 Olmesartan 9 ZnO 9 ROC 8 G-CSF 8 EPA 8 Gel 8 Simvastatin 7 Quinaprilat 7 ICI 7 IL-2 7 Adriamycin 7 Bosentan 7 FAD 7 Bosentan 7 Methyldopa 7 Losartan potassium 7 Bifidobacterium 7 DFP 7 Bestatin 6 dibasic calcium phosphate 6 Lacidipine 5 Indapamide 5 HCG 5 Fosinopril sodium 5 Clonidine 5 Methylprednisolone 5 Lercanidipine 5 CTX 5 ZnCl2 5 DMSA 5 Frontal 5 IFN-gamma 5 Indapamide 5 Prednisone 5 Papain 5 Kenyan 5 Isradipine 5 Activin 5 TTC 5 CTX 5 ZnCl2 5 Vitamin E 4 Isoptin 4 Histamine 4 Sorafenib 4 Lacidipine 4 Coral 4 TAC 4 Lotrel 4 NAG 4 Biopolymers 4 Pravastatin 4 Spectrum 4 CVA 4 CEC 4 Tuberculin 4 Vorinostat 4 Paraffin 4 MgSO4 4 ACT 4 Bortezomib 4 CED 4 Clopidogrel 4 Serum albumin 4 Nitric Oxide 4 Phentolamine 3 Chlorothiazide 3 Methylene blue 3 Gefitinib 3 HCH 3 Tipifarnib 3 Mutagen 3 CaCl2 3 Adenosine triphosphate 3 Nesiritide 3 Ecadotril 3 CaCl2 3 Bevacizumab 3 Nebivolol 3 Liraglutide 3 Pregabalin 3 Darbepoetin alfa 3 Tacrolimus 3 Concor 3 Aliskiren fumarate 3 Norvasc 3 CaCl2 3 Amlodipine besylate 3 Alanine 3 Benazepril hydrochloride 3 Fondaparinux 3 Exenatide 3 ABC 3 ALA 3 PMPA 3 Orion 3 AHF 3 Ringer's solution 3 Pronase 3 Olmesartan medoxomil 3 Ibopamine 3 Epoetin 3 Tolvaptan 3 PTC 3 Atropine 3 more...

Enzyme ACE 18300 renin 3111 PDH 656 CD10 451 kallikrein 241 pyruvate dehydrogenase 164 trypsin 136 ERK 134 superoxide dismutase 128 pyruvate dehydrogenase 123 pyruvate dehydrogenase 123 AGT 120 glucose-6-phosphate dehydrogenase 113 catalase 101 lactate dehydrogenase 96 angiotensin-converting enzyme 2 93 chymase 93 CPN 87 NO synthase 78 pepsin 78 mitogen-activated protein kinase 74 ATPase 72 alkaline phosphatase 72 NADPH oxidase 67 lysozyme 63 acetylcholinesterase 63 peroxidase 60 CD13 59 PDK1 57 NADPH oxidase 54 thermolysin 54 phosphodiesterase 53 protein kinase C 52 tissue plasminogen activator 51 glutathione peroxidase 49 chymotrypsin 48 subtilisin 47 alanine aminotransferase 47 thrombin 47 papain 46 malate dehydrogenase 44 creatine kinase 44 focal adhesion kinase 44 dipeptidyl peptidase IV 43 protein kinase 43 collagenase 40 tissue kallikrein 38 aminopeptidase P 37 MDP 37 PRA 35 MDH 34 MDH 34 glutathione reductase 31 glutathione S-transferase 31 aspartate aminotransferase 31 acid phosphatase 31 proteasome 30 MAP 30 guanylate cyclase 30 cathepsin D 30 CAD 29 CAD 29 CAD 29 reverse transcriptase 27 alcohol dehydrogenase 27 caspase-3 27 NOS 26 carbonic anhydrase 25 gamma-glutamyl transpeptidase 25 15-hydroxyprostaglandin dehydrogenase 24 ACS 24 succinate dehydrogenase 23 endothelin-converting enzyme 23 xanthine oxidase 23 carboxypeptidase A 23 methylenetetrahydrofolate reductase 22 thimet oligopeptidase 22 methylenetetrahydrofolate reductase 22 AMP-activated protein kinase 22 prolyl endopeptidase 21 AMPK 21 alpha-glucosidase 21 lipase 21 cathepsin B 20 BAL 20 phosphorylase 20 cholinesterase 19 laccase 19 plasmin 19 AMPK 19 furin 19 ADH 19 carboxypeptidase B 18 elastase 17 monoamine oxidase 17 urokinase-type plasminogen activator 16 PAH 16 PCP 16 phospholipase C 15 aminopeptidase A 15 thromboplastin 15 leucine aminopeptidase 15 LPL 15 hexokinase 15 phosphofructokinase 14 luciferase 14 phospholipase A2 14 glyceraldehyde-3-phosphate dehydrogenase 14 carboxypeptidase Y 14 tyrosinase 13 lipoxygenase 13 bromelain 13 aldose reductase 13 calcineurin 13 alpha-amylase 13 diaphorase 12 AST 12 citrate synthase 12 lipoprotein lipase 12 aldehyde dehydrogenase 12 CPM 12 cytochrome oxidase 12 transcriptase 11 pyruvate carboxylase 11 cathepsin G 11 caspase-1 11 isocitrate dehydrogenase 11 RNase 11 RNase 11 tryptase 11 aldolase 10 neuraminidase 10 isocitrate dehydrogenase 10 pyruvate kinase 10 glycerol-3-phosphate dehydrogenase 9 MEK 9 6-phosphogluconate dehydrogenase 9 6-phosphogluconate dehydrogenase 9 5'-nucleotidase 9 neurolysin 9 APC 9 aminopeptidase B 9 adenylate cyclase 9 RNA polymerase 9 carboxypeptidase E 9 glycerol-3-phosphate dehydrogenase 9 PGM 9 beta-glucuronidase 8 SCP 8 pyruvate decarboxylase 8 beta-galactosidase 8 glyceraldehyde-3-phosphate dehydrogenase 8 diaphorase 8 CYP3A4 8 ceruloplasmin 8 glyceraldehyde-3-phosphate dehydrogenase 8 complex I 8 HSD 8 glucokinase 7 TPP 7 more...

Compound acetate 8647 Clin 1466 Dec 1408 calcium 1271 DCP 1153 DCP 1153 aldosterone 1102 sodium 959 water 955 Angiotensin II 784 glucose 719 PDH 658 creatinine 588 Ang II 560 oxygen 527 Cardiol 508 salt 486 nitric oxide 425 potassium 417 2,4-dichlorophenol 401 arginine 393 DNA 382 Phe 278 Enalapril 246 leucine 230 phosphate 202 tyrosine 199 alanine 198 zinc 195 proline 190 Gly 186 lysine 172 noradrenaline 154 Bradykinin 151 nitrogen 144 prostacyclin 136 hydrogen 135 Ile 131 TCP 129 His 123 EDTA 121 EDTA 120 LPR 117 urea 116 phenol 116 TCP 115 ethanol 113 TCP 112 TCP 112 iron 111 TNF 109 Losartan 102 ATP 100 sulfate 97 GSH 97 GSH 97 methionine 94 nitrate 91 Perindopril 90 DBP 89 ASA 89 DBP 88 Insulin 87 serine 85 acetonitrile 83 methanol 79 His-Leu 79 Asp 74 cGMP 71 acetic acid 70 SDS 70 cysteine 69 4-chlorophenol 67 threonine 64 DPPH 62 Hoe 62 2,4,6-trichlorophenol 61 CO2 60 Enalaprilat 60 2,4,6-trichlorophenol 59 2,4-D 58 copper 57 galactose 57 NH2 56 Angiotensin I 55 Dial 51 chlorine 50 ammonium 50 Pac 49 H2O2 49 Optimal 48 phosphorus 48 tryptophan 46 NADH 44 tryptophan 43 1,3-dichloro-2-propanol 42 tryptophan 41 tryptophan 41 NADPH 41 NAD 41 NADPH 40 DOCA 40 homocysteine 40 cAMP 39 TOF 39 AMP 39 PGE2 39 Quinapril 38 2-chlorophenol 37 NAD 37 bromide 37 silver 36 Salt 36 5-HT 35 2-chlorophenol 35 PEG 35 L-leucine 35 HCl 35 BNP 34 formic acid 33 2,6-dichlorophenol 33 Sodium 33 DPP 33 formic acid 32 formic acid 32 DEAE 32 formic acid 32 formic acid 32 formic acid 32 formic acid 32 formic acid 32 Telmisartan 32 Digoxin 32 formic acid 32 ADP 32 STZ 32 formic acid 32 acetyl-CoA 32 vitamin D 31 N-acetylcysteine 31 TCA 30 Hydrochlorothiazide 30 MAP 30 ADP 29 glutamate 29 ADP 29 Spironolactone 29 cadmium 28 Benazepril 28 manganese 27 cobalt 27 sodium chloride 27 Fosinopril 27 alcohol dehydrogenase 27 ACTH 27 nicotinamide 27 Indomethacin 27 Salix 26 pentose 26 Candesartan 26 more...

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