Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.15.1 (ACE)
18,300 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The effect of cadmium acetate (1 mg/kg i.p.) on the renin angiotensin system was examined in male Sprague-Dawley rats. Blood pressure, plasma renin activity (PRA) and serum angiotensin converting enzyme (ACE) levels were determined in the rats. Cadmium acetate produced a hypertensive response which was not associated with elevated PRA. However, ACE levels in the serum were significantly decreased in the cadmium-treated group as compared with normal controls (P less than 0.01).
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PMID:Acute effects of cadmium on the renin angiotensin system in rats. 132 27