Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.15.1 (ACE)
 18,300 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The influence of sympathectomy of the ear artery in rabbits on the activity of a number of redox coenzymes inthe vascular wall (lactic, glucose-6-phosphoric, isocitrate, and succinic dehydrogenases: LDH, G-6-PDHm isoCDH, and SDH, respectively) was studied by the quantitative histochemical method. Sympathectomy produced a significant diminution of all the dehydrogenase activities. The effect of adrenalin and noradrenaline on the dehydrogenase activities differed. Adrenalin increased thI LDH activity in the intact perfused artery, but had no effect on the CDH and G-6-PDH. Contrary to adrenalin, noradrenaline increased not only the LDH activity, but also that of the G-6-PDH. The action of noradrenaline on the sympathectomized vessel depended on the place of noadrenaline entrance, i.e. through the intima or the adventitia.
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PMID:[Effect of desympathization and catecholamines on metabolic processes in the rabbit otic artery]. 88 11