Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.15.1 (
ACE
)
18,300
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Angiotensin-converting enzyme inhibitors (ACE-I) are widely used in diseases, such as hypertension, congestive heart failure, and myocardial infarction. Although these drugs are well tolerated, one out of five patients discontinues
ACE
-I due to drug side effects, mainly
chronic cough
. However, the pathogenesis of
ACE
-I-induced cough remains controversial and requires further study. In this review, the mechanisms that are suggested in
ACE
-I-induced cough pathophysiology will be discussed in detail in light of the current literature.
...
PMID:Angiotensin-Converting Enzyme Inhibitors Induce Cough. 3066 25
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