Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.15.1 (
ACE
)
18,300
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
In recent years, many national and international organizations have developed clinical practice guidelines for the most important areas of nephrology. In 1999, the Italian Society of Nephrology (SIN) was one of the first scientific societies to publish (in Giornale Italiano di Nefrologia) the Guidelines for the Treatment of Chronic Renal Failure. Since then, new evidence has accumulated on several aspects of the conservative treatment of chronic kidney disease (CKD). These new data have been included in the present version of the guidelines. The first section of the new guidelines underline the importance of the early detection of CKD and early referral to a nephrologist. The second and third sections are dedicated to the dietetic treatment of chronic renal failure, even when associated with nephrotic syndrome. The fourth section analyzes the anti-hypertensive treatment of renal failure, focusing on the choice of anti-hypertensive drugs to retard the progression of renal failure and reduce cardiovascular mortality. This section highlights the reno-protective role of
ACE
inhibitors and of AII receptor antagonists in diabetic and nondiabetic nephropathies. The
Appendix
describes methods for the evaluation of the patient's nutritional status and for protein intake in chronic renal failure.
...
PMID:[Conservative therapy Guidelines for chronic renal failure]. 1466 3
Purpose:
To report the current status of Robotic approach to creation of Catheterisable channel (CC) with the author's personal experience compared to published literature on technical steps, follow up, and outcomes.
Methods:
CC data was extracted from the prospective database set up for all Robotic pediatric urology procedures performed by the author at his institution. A literature search was then performed to look at the evidence base.
Results:
Eighteen consecutive cases (8M:7F) of Robotic approach to creation of CC was identified and included. All attempted cases were successfully completed without any conversion to open approach. Median age at surgery was 10.75 years (IQR 6.9-16.5); Median OT 197 min (IQR 131-295) with concomitant procedures in 4 cases.
Appendix
was used in 14 cases as CC conduit and distal ureter in 4 cases. Median Length of stay (LOS) was 2.75 days (IQR 2-6) and Median FU 27.3 m. Whilst FU duration is comparable to published series, average OT and LOS was much lower in this series. The LOS in this robotic series is much lower than the author's experience with open approach (2.75 vs. 5.8 days). No major complications postoperatively except for one exit site wound infection managed conservatively. None of the CC have been revised in this series and all channels are patent with 12 F or 14 F admissible catheter size. There were no cases of incontinence related to technique of creation of CC and no incidence of exit site stomal stenosis with use of
ACE
stopper until channel matures and Clean intermittent catheterisation (CIC) is established.
Conclusion:
Robotic approach to CC is feasible, safe with excellent outcomes and minimum morbidity. Robotic complex bladder reconstructive surgery offers some advantages to children compared to open approach but is only currently performed in few tertiary centers with expertise.
...
PMID:Robotic Approach to Creation of Continent Catheterisable Channels-Technical Steps, Current Status, and Review of Outcomes. 3071 32
