Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.4.11.18 (MAP)
7,412 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein MAP 7114 p38 956 MAP kinase 708 ERK 671 ERK1 603 JNK 570 Sep 495 Mol 448 MAPK 410 MEK 303 cytokine 291 methionine aminopeptidase 271 mitogen-activated protein 218 ERK2 190 insulin 188 p42 157 TNF 155 c-Jun 153 phosphatase 153 tyrosine kinase 150 ATP 145 threonine 141 IL-6 140 p38 MAP kinase 130 extracellular signal-regulated kinase 129 caspase-3 119 p44 117 MEK1 117 PKC 114 AP-1 112 angiotensin II 110 LPS 107 p53 107 lipopolysaccharide 104 renin 104 PI3K 97 AKT 94 SBP 92 DBP 91 CO2 90 TNF-alpha 86 SAP 85 collagen 84 inducible nitric oxide synthase 84 Bcl-2 83 IL-8 81 microtubule-associated protein 79 nitric oxide synthase 76 c-fos 72 Raf-1 70 BRAF 67 EGF 66 tumor necrosis factor 65 PI3 65 mTOR 64 JNK1 63 IL-10 61 p21 60 ROS 60 chemokine 59 Ang II 59 Rho 59 phosphatidylinositol 3-kinase 58 DAP 57 epidermal growth factor 56 hemoglobin 55 AMP 54 ICP 54 polypeptide 53 Pseudomonas 53 TLR4 53 COX-2 52 GTP 50 MEKK 49 PI3-kinase 49 CREB 49 calmodulin 48 epidermal growth factor receptor 48 STAT 45 PKA 45 more...

Disease cancer 517 hypertension 324 tumor 309 stroke 163 diabetes 105 breast cancer 105 ischemia 104 Alzheimer's disease 84 atherosclerosis 70 carcinoma 67 sepsis 66 melanoma 66 Mycobacterium 65 sepsis 65 depression 62 heart failure 59 obesity 55 neuroblastoma 55 ICP 54 carcinogenesis 54 NAME 53 cold 51 pertussis 50 tumor growth 49 tumorigenesis 48 colorectal cancer 47 hepatocellular carcinoma 47 ATM 47 SDS 43 essential hypertension 42 SEM 41 leukemia 41 MCF 40 HIV 40 adenocarcinoma 36 cardiovascular disease 35 renal disease 35 GSH 34 metastases 34 prostate cancer 33 glioma 33 tumor progression 32 preeclampsia 28 myocardial infarction 27 Blocking 26 lung cancer 26 Johne's disease 25 proteinuria 24 rheumatoid arthritis 24 hyperglycemia 23 arthritis 22 type 2 diabetes 22 infectious diseases 22 asthma 22 erectile dysfunction 22 ovarian cancer 21 myocardial ischemia 21 colon cancer 21 immunodeficiency 21 lymphoma 20 tuberculosis 20 renal failure 19 polyposis 19 schizophrenia 18 gastric cancer 18 Crohn's disease 18 AIDS 18 cerebral ischemia 18 dementia 18 MAC 17 squamous cell carcinoma 17 ventricular hypertrophy 17 Parkinson's disease 17 coronary artery disease 17 pancreatic cancer 15 renal cell carcinoma 15 colitis 15 pulmonary hypertension 15 multiple myeloma 15 acute myeloid leukemia 15 more...

Symptom anesthesia 178 pain 55 analgesia 30 hypercapnia 27 hypothermia 18 starvation 16 collapse 15 diarrhea 14 seizures 13 fatigue 11 overweight 9 exhaustion 8 cough 7 respiratory distress 6 vomiting 6 hypocapnia 6 dyspnea 6 hyperoxia 5 chills 5 exertional dyspnea 5 nausea 5 acidity 4 functional recovery 4 syncope 4 sinus pressure 4 acute stress 4 headache 4 flushing 4 presyncope 3 skin damage 3 discomfort 3 anorexia 3 discomfort 3 spasm 3 thinning 3 Sedation 3 nausea and vomiting 3 tremor 3 pelvic pain 3 paresis 3 cachexia 2 sleepiness 2 weakness 2 constipation 2 memory loss 2 angina 2 wheezing 2 neck pain 2 ataxia 2 colic 2 tachypnea 2 HSA 2 polyuria 2 lethargy 1 Postoperative nausea and vomiting 1 vertigo 1 general problem 1 DNA marker 1 ENT 1 dystonia 1 skin irritation 1 regurgitation 1 Diaphragmatic weakness 1 phosphatemia 1 bradypnea 1 asthenia 1 muscle cramps 1 bitter taste 1 Neuropathic pain 1 tinnitus 1 hypotonia 1 acute pain 1 muscle rigidity 1 Organ failure 1 sneezing 1 shortness of breath 1 scaly skin 1 Tenderness 1 impaired body balance 1 apathy 1 more...

Drug MAP 7114 Cardiovasc 72 ROS 60 lysine 41 IL-2 36 CSF 31 Monit 31 Angiotensin II 20 Ringer's solution 18 nitroglycerin 17 IFN-gamma 17 vitamin E 16 Dermatol 15 caffeine 15 Ethanol 15 Nephron 13 Captopril 12 Leaf 11 NADH 11 Taxol 11 PCP 11 ascorbate 10 ETS 9 ETA 9 Propofol 8 CTX 8 Nitric Oxide 7 Asn 7 uPA 7 EE2 6 IFN-beta 6 TAK 6 ICI 6 DMAP 6 Imatinib 6 Indomethacin 6 Dial 6 PTH 5 Asthma 5 Biopolymers 5 Clonidine 5 ROC 5 Albumin 5 Capsicum 4 Fentanyl 4 Adenosine triphosphate 4 Ouabain 4 PTC 4 TAT 4 Estrogens 4 Gel 4 MOF 4 Glutathione 4 Adriamycin 4 Sodium nitroprusside 4 citric acid 4 Sorafenib 4 TTC 3 HCH 3 ABC 3 Arimidex 3 Growth hormone 3 IL-1ra 3 Apomorphine 3 Infliximab 3 Gleevec 3 BH4 3 Hydroxyethylstarch 3 Lactic Acid 3 Heme 3 Forskolin 3 Histamine 3 Atropine 3 Phosphoramidon 3 Phentolamine 3 Infliximab 3 IL-11 3 -deoxyadenosine 3 Enalaprilat 3 Retinoic acid 3 more...

Enzyme MAP 7412 mitogen-activated protein kinase 1909 ERK 799 MEK 435 protein kinase 388 protein kinase C 256 focal adhesion kinase 130 renin 104 caspase-3 86 MEKK1 67 calcineurin 62 phosphatidylinositol 3-kinase 58 superoxide dismutase 52 luciferase 48 NO synthase 47 cdc2 47 catalase 41 NADPH oxidase 40 phospholipase C 40 ATPase 39 proteasome 35 thrombin 33 NADPH oxidase 33 PARP 31 phosphoinositide 3-kinase 31 peroxidase 30 ACE 30 IKK 29 NOS 29 GSK 28 glutathione S-transferase 26 phospholipase A2 25 phosphodiesterase 24 alkaline phosphatase 24 collagenase 23 CaMKII 22 trypsin 22 lactate dehydrogenase 21 AMPK 21 creatine kinase 20 kinesin 19 adenylate cyclase 19 alanine aminotransferase 18 prolidase 17 MAT 17 MAT 17 aspartate aminotransferase 16 reverse transcriptase 15 peptide deformylase 15 APC 15 ACS 14 ornithine decarboxylase 14 MIP 14 AMP-activated protein kinase 13 PRA 13 caspase-9 13 glutathione peroxidase 13 protein phosphatase 2A 11 RNA polymerase 11 PCP 11 lipoxygenase 11 urokinase-type plasminogen activator 11 phospholipase D 10 PAH 10 glyceraldehyde-3-phosphate dehydrogenase 10 AMPK 9 lipase 9 topoisomerase 9 MMP-3 9 heme oxygenase 9 guanylate cyclase 9 AST 9 tyrosine hydroxylase 9 PTPase 8 CD13 8 MMP 8 topoisomerase 8 CD10 8 alcohol dehydrogenase 8 peroxiredoxin 7 more...

Compound MAP 7114 Dec 524 oxygen 524 DNA 428 tyrosine 424 calcium 315 sodium 263 Clin 236 water 234 MEK 233 threonine 198 nitric oxide 196 serine 194 acetate 173 glucose 157 TNF 155 ATP 145 methionine 141 arginine 129 CO2 128 cAMP 117 phosphate 112 salt 99 DBP 91 DBP 91 hydrogen 82 nitrogen 74 lysine 67 glutamate 61 Diazepam 60 alanine 60 cysteine 58 AMP 57 DAP 57 DAP 57 potassium 56 noradrenaline 53 leucine 52 GTP 50 ethanol 50 proline 50 creatinine 47 Asp 45 SDS 44 His 44 Ang II 42 NH2 42 Phe 41 cobalt 40 zinc 40 Cardiol 40 Insulin 38 cGMP 38 GSH 37 GSH 37 ammonium 36 aldosterone 35 iron 34 MDA 34 phosphorus 33 MTT 33 H2O2 32 PMA 32 ASA 31 glycerol 31 PMA 31 THP 31 COS 30 Angiotensin II 29 THP 28 Gly 28 manganese 27 Tyrosine 26 sulfate 26 PAP 25 PAP 25 ADP 25 PAP 25 N2O 24 CPP 24 more...

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