Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: EC:3.4.11.18 (MAP)
7,412 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein MAP 7114 p38 956 MAP kinase 708 ERK 671 ERK1 603 JNK 570 Sep 495 Mol 448 MAPK 410 MEK 303 cytokine 291 methionine aminopeptidase 271 mitogen-activated protein 218 ERK2 190 insulin 188 p42 157 TNF 155 c-Jun 153 phosphatase 153 tyrosine kinase 150 ATP 145 threonine 141 IL-6 140 p38 MAP kinase 130 extracellular signal-regulated kinase 129 caspase-3 119 MEK1 117 p44 117 PKC 114 AP-1 112 angiotensin II 110 LPS 107 p53 107 renin 104 lipopolysaccharide 104 PI3K 97 AKT 94 SBP 92 DBP 91 CO2 90 more...

Disease cancer 517 hypertension 324 tumor 309 stroke 163 breast cancer 105 diabetes 105 ischemia 104 Alzheimer's disease 84 atherosclerosis 70 carcinoma 67 melanoma 66 sepsis 66 Mycobacterium 65 sepsis 65 depression 62 heart failure 59 obesity 55 neuroblastoma 55 carcinogenesis 54 ICP 54 NAME 53 cold 51 pertussis 50 tumor growth 49 tumorigenesis 48 hepatocellular carcinoma 47 ATM 47 colorectal cancer 47 SDS 43 essential hypertension 42 leukemia 41 SEM 41 HIV 40 MCF 40 adenocarcinoma 36 cardiovascular disease 35 renal disease 35 GSH 34 metastases 34 prostate cancer 33 more...

Symptom anesthesia 178 pain 55 analgesia 30 hypercapnia 27 hypothermia 18 starvation 16 collapse 15 diarrhea 14 seizures 13 fatigue 11 overweight 9 exhaustion 8 cough 7 hypocapnia 6 respiratory distress 6 vomiting 6 dyspnea 6 hyperoxia 5 nausea 5 chills 5 exertional dyspnea 5 flushing 4 functional recovery 4 syncope 4 headache 4 acidity 4 acute stress 4 sinus pressure 4 anorexia 3 skin damage 3 discomfort 3 thinning 3 presyncope 3 spasm 3 paresis 3 Sedation 3 pelvic pain 3 nausea and vomiting 3 discomfort 3 tremor 3 more...

Drug MAP 7114 Cardiovasc 72 ROS 60 lysine 41 IL-2 36 Monit 31 CSF 31 Angiotensin II 20 Ringer's solution 18 IFN-gamma 17 nitroglycerin 17 vitamin E 16 Dermatol 15 caffeine 15 Ethanol 15 Nephron 13 Captopril 12 Taxol 11 NADH 11 Leaf 11 PCP 11 ascorbate 10 ETS 9 ETA 9 Propofol 8 CTX 8 Asn 7 Nitric Oxide 7 uPA 7 Dial 6 IFN-beta 6 DMAP 6 TAK 6 ICI 6 EE2 6 Imatinib 6 Indomethacin 6 PTH 5 Clonidine 5 ROC 5 more...

Enzyme MAP 7412 mitogen-activated protein kinase 1909 ERK 799 MEK 435 protein kinase 388 protein kinase C 256 focal adhesion kinase 130 renin 104 caspase-3 86 MEKK1 67 calcineurin 62 phosphatidylinositol 3-kinase 58 superoxide dismutase 52 luciferase 48 NO synthase 47 cdc2 47 catalase 41 phospholipase C 40 NADPH oxidase 40 ATPase 39 proteasome 35 NADPH oxidase 33 thrombin 33 phosphoinositide 3-kinase 31 PARP 31 ACE 30 peroxidase 30 NOS 29 IKK 29 GSK 28 glutathione S-transferase 26 phospholipase A2 25 alkaline phosphatase 24 phosphodiesterase 24 collagenase 23 CaMKII 22 trypsin 22 lactate dehydrogenase 21 AMPK 21 creatine kinase 20 more...

Compound MAP 7114 Dec 524 oxygen 524 DNA 428 tyrosine 424 calcium 315 sodium 263 Clin 236 water 234 MEK 233 threonine 198 nitric oxide 196 serine 194 acetate 173 glucose 157 TNF 155 ATP 145 methionine 141 arginine 129 CO2 128 cAMP 117 phosphate 112 salt 99 DBP 91 DBP 91 hydrogen 82 nitrogen 74 lysine 67 glutamate 61 Diazepam 60 alanine 60 cysteine 58 AMP 57 DAP 57 DAP 57 potassium 56 noradrenaline 53 leucine 52 proline 50 ethanol 50 more...

---