Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.11.18 (
MAP
)
7,412
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MAP
7114
p38
956
MAP kinase
708
ERK
671
ERK1
603
JNK
570
Sep
495
Mol
448
MAPK
410
MEK
303
cytokine
291
methionine aminopeptidase
271
mitogen-activated protein
218
ERK2
190
insulin
188
p42
157
TNF
155
phosphatase
153
c-Jun
153
tyrosine kinase
150
more...
Disease
cancer
517
hypertension
324
tumor
309
stroke
163
breast cancer
105
diabetes
105
ischemia
104
Alzheimer's disease
84
atherosclerosis
70
carcinoma
67
melanoma
66
sepsis
66
Mycobacterium
65
sepsis
65
depression
62
heart failure
59
obesity
55
neuroblastoma
55
carcinogenesis
54
ICP
54
more...
Symptom
anesthesia
178
pain
55
analgesia
30
hypercapnia
27
hypothermia
18
starvation
16
collapse
15
diarrhea
14
seizures
13
fatigue
11
overweight
9
exhaustion
8
cough
7
respiratory distress
6
dyspnea
6
vomiting
6
hypocapnia
6
nausea
5
chills
5
hyperoxia
5
more...
Drug
MAP
7114
Cardiovasc
72
ROS
60
lysine
41
IL-2
36
Monit
31
CSF
31
Angiotensin II
20
Ringer's solution
18
IFN-gamma
17
nitroglycerin
17
vitamin E
16
Dermatol
15
Ethanol
15
caffeine
15
Nephron
13
Captopril
12
Leaf
11
Taxol
11
NADH
11
more...
Enzyme
MAP
7412
mitogen-activated protein kinase
1909
ERK
799
MEK
435
protein kinase
388
protein kinase C
256
focal adhesion kinase
130
renin
104
caspase-3
86
MEKK1
67
calcineurin
62
phosphatidylinositol 3-kinase
58
superoxide dismutase
52
luciferase
48
NO synthase
47
cdc2
47
catalase
41
NADPH oxidase
40
phospholipase C
40
ATPase
39
more...
Compound
MAP
7114
Dec
524
oxygen
524
DNA
428
tyrosine
424
calcium
315
sodium
263
Clin
236
water
234
MEK
233
threonine
198
nitric oxide
196
serine
194
acetate
173
glucose
157
TNF
155
ATP
145
methionine
141
arginine
129
CO2
128
more...