Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.4.11.18 (MAP)
 7,412 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
METAP1 12.1
Caspase recruitment domain-containing protein 14 12.1
TSC22 domain family, member 4 12.1
CCDC138 12.1
Microtubule-associated protein 2 kinase 12.1
MAP 12.1
G6f protein 12.1
methionine aminopeptidase 12.0
ARL6IP2 11.1
FIZ1 11.1
ZNF716 11.1
AURORA2 11.1
ZNF821 11.1
HOR5 11.1
Peptidase M 11.1
KIAA1328 11.1
MAP kinase phosphatase 4 11.1
Sma- and Mad-related protein 1 11.1
RAB39A 10.5
HSH2D 10.5
IL8R2 10.5
FAM179A 10.5
SAP-1a 10.2
OPAL1 10.1
PP2Czeta 10.1
PPM1J 10.1
NKIAMRE 10.1
WDR90 10.1
LPCAT4 10.1
TGF-beta activated kinase 10.1
MAP3K15 9.7
Ribosomal protein S27a 9.7
MAP kinase phosphatase 5 9.7
TXLNA 9.7
Dual specificity phosphatase 1 9.7
LRRC37A 9.7
protein kinase C, alpha 9.7
SMAD 5 9.7
hSOS1 9.7
DUSP7 9.5
C-type lectin domain family 3 member A 9.5
teratocarcinoma-derived growth factor 1 9.5
TUBB3 protein 9.5
DUSP27 9.5
UPK1B 9.5
ERK4 9.4
MCFP 9.4
DUSP26 9.4
EHBP1L1 9.3
FBXO15 9.3
PPEF-2 9.3
EIF4F 9.3
cytosolic aminopeptidase P 9.3
KIAA1267 9.3
adducin 1 9.3
MORG1 9.3
TRAP1 protein 9.3
PTP-SL 9.2
MKP-4 9.2
ERK3 9.1
Junctional adhesion molecule 4 9.1
RanBP7 9.1
SASS6 9.1
RNF219 9.1
G6f 9.1
TRPM2 protein 9.1
MAP 1 9.0
PSME3 9.0
ABIN-2 8.9
MAP4K5 8.9
RAB3IP 8.9
DBN1 8.9
HPTP epsilon 8.9
DDX59 8.9
MAPKK6 8.9
TTLL7 8.9
ENDOD1 8.9
CD158i 8.9
NEK11 8.9
DUSP14 8.8
TAO2 8.8
MKP-5 8.8
MKP-3 8.8
Tpr1 8.7
T-cell death-associated gene 51 8.7
TBC1D2 8.7
GRB2 protein 8.7
POPDC2 8.7
MITOCHONDRIAL 8.7
RVR 8.6
glutamate decarboxylase GAD65 8.6
LARP 8.6
MAST205 8.6
Microtubule-associated protein 1A 8.6
MINK 8.6
DYNC2LI1 8.6
CMTM7 8.6
TMDP 8.6
erk 8.6
PAWP 8.6
microtubule-associated protein 4 8.5
FSL1 8.5
TGFBRAP1 8.5
MOSP 8.5
extracellular signal-regulated kinase 3 8.5
MAP 4 8.5
protein inhibitor of activated STAT-1 8.5
HCNP 8.5
LEMD2 8.5
MKP1 8.5
MAP kinase 8.4
DUSP9 8.4
calmodulin 3 8.4
KATANIN 8.4
PPM1K 8.4
Spred-2 8.4
RHOQ 8.4
UHMK1 8.4
UBE2V1 8.4
layilin 8.4
MARK3 8.4
Microtubule-associated protein 1B 8.4
MAP 2 8.4
MAP-1 8.3
DUSP2 8.3
GNRH2 8.3
RNA helicase) 8.3
PAOX 8.3
E-MAP-115 8.3
RAB8 8.3
TGF-beta activated kinase 1 8.3
MKP-1 8.2
MNK2 8.2
tripeptidyl-peptidase II 8.2
POPDC1 8.2
PP2Cm 8.2
ANKRD55 8.2
INPP4A 8.2
38kD 8.2
Receptor-interacting protein 2 8.2
C13orf25 8.2
STK31 8.2
SCHIP1 8.2
DENND5A 8.2
H-REV107-1 8.2
MAP3 8.1
DUSP10 8.1
MAP-2 8.1
GOSR2 8.1
MRGPRD 8.1
XPNPEP2 8.1
CLK4 8.1
MAP kinase phosphatase 3 8.1
MKK5 8.1
IRAK-2 8.0
KIAA1549:BRAF 8.0
Extracellular signal-regulated kinase 3 8.0
DNAJB4 8.0
CLNS1A 8.0
Microtubule-associated protein 2 8.0
more...
Disease
birth; prolonged 12.1
RP27 10.5
EDV2 10.1
Segmental glomerulosclerosis 9.7
SPERM 8.5
AD7 8.2
MYH-associated polyposis 7.9
AD4 7.6
bacterial colitis 7.6
Acute gouty arthritis 7.5
FVR 7.1
high renin hypertension 6.9
Camelpox 6.9
PCP abuse 6.9
NINA 6.8
AAT2 6.7
DMAT 6.7
Reflex bradycardia 6.6
Prolidase deficiency 6.6
recurrent osteosarcoma 6.6
Johne's disease 6.5
traumatic lung 6.3
FBD 6.3
Intestinal pseudo-obstruction 6.2
Pannus 6.2
Renal scarring 6.2
Microaneurysms 6.1
Goldblatt hypertension 6.0
Ventricular septal rupture 6.0
Renal interstitial fibrosis 6.0
FRA 5.8
EDS1 5.7
Herpesvirus infection 5.6
Opioid use disorder 5.5
alcoholic neuropathy 5.4
Splenic marginal zone lymphoma 5.4
SBH 5.4
SBH 5.4
Axenfeld-Rieger syndrome 5.4
Bezold 5.3
DSH 5.3
infectious enteritis 5.3
endotoxic shock 5.3
AAT1 5.3
neurogenic hypertension 5.3
BDB 5.2
metabolic syndrome X 5.2
microsporidiosis 5.2
muscle swelling 5.2
Cornelia de Lange 5.2
Autonomic dysreflexia 5.1
regional enteritis 5.1
Dystrophic epidermolysis bullosa 5.1
ED3 5.0
LAP 5.0
EME 5.0
RSS 4.9
PTP 4.9
lung neoplasm 4.8
SCP 4.8
traumatic coma 4.8
HES 4.8
atypical mycobacterial infection 4.8
Gingival overgrowth 4.7
Squamous Cell Carcinoma 4.7
MEST 4.7
induced psychosis 4.7
GAN 4.7
Fibrosarcoma 4.6
VISA 4.6
HLP 4.6
Primary open-angle glaucoma 4.5
ICP 4.5
chronic enteritis 4.5
splenic marginal zone lymphoma 4.5
Fahr's disease 4.5
Globus 4.4
HGF 4.4
DRM 4.4
HYP 4.4
Neuromuscular blockade 4.4
kidney hypertrophy 4.4
CLS 4.4
Exercise-induced asthma 4.4
X-linked lymphoproliferative syndrome 4.4
psychomotor impairment 4.3
vascular dilation 4.3
antidiuresis 4.3
Pregnancy-induced hypertension 4.3
cardiac overload 4.3
TNS 4.3
ATRX 4.3
Hemangiopericytoma 4.3
Hemangiopericytoma 4.3
CHR 4.3
PPB 4.2
Ototoxicity 4.2
Pneumoperitoneum 4.2
CP1 4.2
benign nevi 4.2
hyaline membrane disease 4.2
legal blindness 4.2
CIE 4.2
Spitz nevus 4.1
CAE 4.1
vascular headache 4.1
HHS 4.1
HHS 4.1
HIV encephalopathy 4.1
NAME 4.1
OPS 4.1
Degos 4.1
polyposis 4.0
CAE 4.0
AHL 4.0
Inattention 4.0
HBD 4.0
West Nile fever 4.0
TEC 4.0
ATM 4.0
acute cystitis 3.9
FSS 3.9
Interstitial fibrosis 3.9
cerebral aneurysm 3.9
diabetic angiopathy 3.9
LDS 3.9
EL4 3.9
PMT 3.9
SIRS 3.9
fluid overload 3.9
hypertension in pregnancy 3.8
SVD 3.8
Costello syndrome 3.8
EGC 3.8
borderline hypertension 3.8
renal hypertension 3.8
HRA 3.8
Chimera 3.8
MAC 3.8
BEN 3.8
Spraying 3.8
blood cancer 3.8
CLN1 3.8
flashbacks 3.8
hypertensive nephropathy 3.8
hormone refractory prostate cancer 3.8
erectile dysfunction 3.8
pancreatic abscess 3.8
alpha thalassemia 3.8
gastrointestinal infection 3.7
Brain stem 3.7
CYLD 3.7
alcoholic cardiomyopathy 3.7
Peutz-Jeghers syndrome 3.7
Goldblatt 3.7
XPB 3.7
OPA1 3.7
SVD 3.7
FDC 3.6
essential hypertension 3.6
more...
Symptom
impaired body balance 9.7
Diaphragmatic weakness 7.8
Organ failure 6.1
phosphatemia 5.3
sinus pressure 5.0
leg cramps 4.9
scaly skin 4.6
bradypnea 4.4
presyncope 4.4
Postoperative nausea and vomiting 4.0
hypocapnia 3.9
hypercapnia 3.9
Tenderness 3.5
Sedation 3.3
loss of balance 3.2
Halo 3.2
skin damage 3.1
anesthesia 2.8
exertional dyspnea 2.7
chills 2.3
general problem 2.3
muscle cramps 2.2
DNA marker 2.2
analgesia 2.2
hypothermia 2.2
hyperoxia 2.0
muscle rigidity 2.0
acute stress 1.9
tachypnea 1.8
pelvic pain 1.7
bitter taste 1.6
Neuropathic pain 1.6
HSA 1.5
polyuria 1.5
starvation 1.5
colic 1.4
flushing 1.4
despair 1.4
exhaustion 1.3
memory loss 1.2
oliguria 1.2
sneezing 1.2
collapse 1.2
paresis 1.1
neck pain 1.1
skin irritation 1.0
syncope 0.9
bradykinesia 0.9
wheezing 0.8
spasm 0.8
asthenia 0.7
shoulder pain 0.6
cachexia 0.6
snoring 0.6
overweight 0.6
nausea and vomiting 0.4
respiratory distress 0.4
functional recovery 0.4
cough 0.3
thinning 0.2
acidity 0.2
acute pain 0.1
apathy 0.1
diarrhea 0.1
anorexia -0.1
dyspnea -0.1
nausea -0.1
fatigue -0.1
pain -0.1
paresthesia -0.2
constipation -0.3
numbness -0.3
shortness of breath -0.3
ENT -0.3
vomiting -0.3
lethargy -0.4
hypotonia -0.4
tremor -0.5
seizures -0.5
sleepiness -0.6
tinnitus -0.6
vertigo -0.7
discomfort -0.8
ataxia -0.9
discomfort -0.9
regurgitation -0.9
dystonia -1.0
angina -1.3
headache -1.7
weakness -2.1
abdominal pain -2.9
Drug
Dopascan 12.1
MAP 10.9
Ovalicin 10.5
Spiraprilat 10.5
Xaliproden 10.5
Enisoprost 8.5
Alsterpaullone 8.5
Flurbiprofen axetil 8.4
Piroximone 8.1
Daltroban 7.7
Olomoucine 7.6
Hydroxyethylstarch 7.0
Morphine hydrochloride 6.9
Ciglitazone 6.8
MT6 6.7
Eucalyptus oil 6.7
Oxycon 6.5
Calcium gluconate 6.5
Arimidex 6.5
Bethanidine 6.4
Enalaprilat 6.4
Enalaprilat 6.4
Lactic Acid 6.4
Terlipressin 6.3
Terlipressin 6.3
Norgestomet 6.2
Lercanidipine 6.2
Dopexamine 6.1
Phosphoramidon 5.9
Pegvisomant 5.7
Midodrine 5.6
Batimastat 5.5
Batimastat 5.5
Abatacept 5.4
Glybenclamide 5.4
Sodium acetate 5.4
Lacidipine 5.3
Onconase 5.3
Fluticasone propionate 5.2
Sesamol 5.2
Lacidipine 5.1
Hyperforin 5.0
Vandetanib 5.0
CEX 5.0
Vinpocetine 4.9
Molsidomine 4.8
Ringer's solution 4.8
Lead acetate 4.8
Methyldopa 4.8
TAK 4.7
3-Methyladenine 4.7
Malachite Green 4.6
Bromelain 4.6
Felodipine 4.5
Gemzar 4.5
DMAP 4.5
Captopril 4.5
Casodex 4.5
Ranibizumab 4.4
Pramipexole 4.4
Tranilast 4.4
Flavopiridol 4.4
Diamminedichloroplatinum 4.4
Pramipexole 4.3
Survanta 4.3
Poloxamer 188 4.3
Adenosine triphosphate 4.3
Calcium chloride 4.2
OMP 4.2
Ginger 4.2
Escitalopram 4.1
Sodium nitroprusside 4.1
RAL 4.1
Angiotensin II 4.1
Citric acid 4.1
Magnesium sulfate 4.1
Propofol 4.0
Troglitazone 4.0
Areca 4.0
Guanethidine 4.0
Papain 3.9
CLS 3.9
Taxol 3.9
ETS 3.9
IPD 3.8
uPA 3.8
Levosimendan 3.8
ETA 3.8
Clomiphene citrate 3.8
Fentanyl 3.7
ROS 3.7
Depo-Provera 3.7
Gemfibrozil 3.7
Perindopril 3.7
PCP 3.7
K-252a 3.6
Fulvestrant 3.6
Nitric Oxide 3.5
IL-11 3.5
Erlotinib 3.5
Infliximab 3.5
Sorafenib 3.5
Infliximab 3.5
Modafinil 3.5
Phentolamine 3.4
Apomorphine 3.4
Imatinib 3.4
MDM 3.4
CoCl2 3.4
CoCl2 3.4
Bosentan 3.3
Bosentan 3.3
Rolipram 3.3
PTC 3.3
Trifluoperazine 3.3
Gastro 3.2
IL-1ra 3.2
DEX 3.2
ISP 3.2
Valsartan 3.2
Gleevec 3.2
KGF 3.2
Clonidine 3.2
PFT 3.1
GRF 3.1
IFN-beta 3.1
MTC 3.1
BH4 3.1
nitroglycerin 3.0
AIC 3.0
Neoral 3.0
Antithrombin III 3.0
Sinemet 3.0
Indocyanine green 2.9
Estrogens 2.9
Capsicum 2.9
Diurnal 2.9
AMC 2.9
CEC 2.8
Gefitinib 2.8
TAT 2.8
Dasatinib 2.8
Urokinase 2.8
TTC 2.8
Ouabain 2.8
Glide 2.8
Pilocarpine 2.7
CCL 2.7
Pronase 2.7
Ethanol 2.7
PDL 2.7
Lovastatin 2.7
-deoxyadenosine 2.6
Raloxifene 2.6
DHT 2.5
G418 2.5
MOF 2.5
DMSA 2.5
DHT 2.5
CIA 2.5
more...
Enzyme
MAP 12.1
creatinase 8.4
peptide deformylase 8.0
Aeromonas proteolytica aminopeptidase 7.9
ketopantoate hydroxymethyltransferase 7.7
MEKK1 7.3
prolidase 7.2
aminopeptidase P 7.1
MT 1 6.9
nepenthesin 6.8
MEK 6.7
GK2 6.6
mitogen-activated protein kinase 6.4
peptidyl-tRNA hydrolase 6.3
decarbonylase 6.3
NSY 6.2
CLK1 6.1
dynein ATPase 6.1
N-acetylglucosamine deacetylase 6.0
NADPH:quinone oxidoreductase 5.7
glycerophosphodiester phosphodiesterase 5.6
MAT 5.6
spermine synthase 5.6
TSR 5.6
neuropsin 5.4
quinolinic acid phosphoribosyltransferase 5.4
MAT 5.4
transcarboxylase 5.3
LMT 5.3
pantetheinase 5.3
polyphosphatase 5.2
ERK 5.2
glycoprotease 5.1
PTPase 5.1
PRA 5.1
methionyl-tRNA synthetase 5.1
tripeptidase 5.0
prolinase 4.9
CTD kinase 4.9
CPN 4.9
hepsin 4.9
hepsin 4.9
caspase-7 4.8
SCP 4.8
caspase-7 4.8
neuropsin 4.8
BIS 4.8
BBE 4.7
oxaloacetate decarboxylase 4.7
pyroglutamate aminopeptidase 4.7
IKK 4.7
Der p 1 4.6
Lys4 4.6
cdc2 4.6
nitrile hydratase 4.6
caspase-10 4.6
glutamyl-tRNA synthetase 4.6
CaMKII 4.6
caspase-10 4.5
histamine N-methyltransferase 4.5
GD3 synthase 4.5
phosphoinositide 3-kinase 4.5
phosphatidylinositol 3-kinase 4.5
protein kinase C 4.5
NQO2 4.5
PMT 4.4
carboxypeptidase E 4.4
15-hydroxyprostaglandin dehydrogenase 4.4
protein kinase 4.4
endothelin-converting enzyme 4.3
stilbene synthase 4.3
lysophospholipase D 4.3
S-adenosylmethionine decarboxylase 4.3
neutral sphingomyelinase 4.3
cysteine dioxygenase 4.3
phosphatidylinositol 4-kinase 4.2
glycerol dehydrogenase 4.2
methylthioadenosine phosphorylase 4.2
stilbene synthase 4.2
glycerol dehydrogenase 4.2
GSK 4.1
sphingosine kinase 4.1
NOS 4.1
kinesin 4.0
m-calpain 4.0
protein phosphatase 2A 4.0
calcineurin 4.0
NADPH oxidase 3.9
dimethylarginine dimethylaminohydrolase 3.8
protein farnesyltransferase 3.8
NADPH oxidase 3.8
UDP-glucose dehydrogenase 3.8
BAL 3.7
inositol phosphatase 3.7
NO synthase 3.7
focal adhesion kinase 3.7
PCP 3.7
renin 3.6
MIP 3.6
PDO 3.6
alanine aminopeptidase 3.6
PME 3.5
CEP 3.5
phospholipase D 3.5
peroxiredoxin 3.5
FAST 3.5
MMP-3 3.5
SPS 3.4
leucine aminopeptidase 3.4
caspase-3 3.4
PKG 3.4
aminopeptidase A 3.4
calpain 3 3.3
carboxypeptidase Y 3.3
PARP 3.3
choline kinase 3.3
PAH 3.3
beta-amylase 3.3
ADH 3.3
PDK1 3.3
CD13 3.3
SPT 3.3
myosin light chain kinase 3.3
ornithine decarboxylase 3.2
polyamine oxidase 3.2
phospholipase C 3.2
Rex 3.2
STK11 3.2
heme oxygenase 3.2
DCF 3.1
thioredoxin reductase 3.1
CYP7A1 3.1
farnesyltransferase 3.0
MMP 3.0
SPT 3.0
CEP 3.0
glyceraldehyde-3-phosphate dehydrogenase 2.9
thromboxane synthase 2.9
GRK5 2.9
isopeptidase 2.9
glycine decarboxylase 2.9
myrosinase 2.9
PI-PLC 2.9
phospholipase A2 2.9
1-hydroxylase 2.9
caspase-9 2.9
glycerol-3-phosphate dehydrogenase 2.9
AMPK 2.9
hexosaminidase 2.9
TAT 2.8
glycerol-3-phosphate dehydrogenase 2.8
HDR 2.8
arylsulfatase 2.8
ACE 2.8
carboxypeptidase B 2.8
PAM 2.8
cysteine synthase 2.8
MPP 2.8
tissue kallikrein 2.8
porphobilinogen deaminase 2.8
more...
Compound
MAP 11.7
Chromophore I 11.1
Ovalicin 10.5
CO 11 10.1
C8H16O2 9.7
Trilobolide 9.7
4-cyclohexene-1,2-dicarboxylic acid 9.5
Nopinone 9.5
Cronolone 9.5
4-cyclohexene-1,2-dicarboxylic acid 9.5
3,5-octanedione 9.3
I 27 9.3
1,2,4,5-benzenetetramine 9.1
PHPS 8.9
15S-hydroxyeicosatrienoic acid 8.7
Epimestrol 8.7
Rubratoxin B 8.7
C10H16O4 8.6
13-Hydroxyoctadecadienoic acid 8.5
Regulin 8.5
2-amino-4-methylphenol 8.4
Indicine N-oxide 8.4
Diaspirin 8.1
butyl benzoate 8.1
2,3-octanedione 8.0
Spinasterol 7.8
DL-Penicillamine 7.8
DAP 7.8
DAP 7.8
Regulin 7.7
Decursinol 7.7
Medroxyprogesterone 7.7
2-amino-3H-phenoxazin-3-one 7.7
FBF 7.7
LBF 7.6
2-methylanthracene 7.5
Anacardic acid 7.2
H-3 7.2
Epinine 7.1
EXP 3174 7.1
1-penten-3-ol 7.0
Trimethaphan 7.0
Physcion 7.0
HNa 7.0
Protopine 6.9
Sinigrin 6.9
Esmolol 6.8
Inactin 6.8
Thiorphan 6.7
DBP 6.7
Angelicin 6.6
Prodigiosin 6.6
Prodigiosin 6.6
Tiapamil 6.5
DBP 6.5
3-methylbutanal 6.5
Enalaprilat 6.4
4-methoxycinnamic acid 6.4
TCTP 6.4
Urapidil 6.4
Scoparone 6.3
Danthron 6.3
MEK 6.3
Exemestane 6.3
Tetrabenazine 6.2
2,4,6-trimethylphenol 6.2
Echinomycin 6.2
2,4,6-trimethylphenol 6.1
ICI 164384 6.0
6R-BH4 6.0
cyclopropanecarboxylic acid 6.0
HOG 6.0
Metaproterenol 6.0
cyclopropanecarboxylic acid 6.0
2-ethyl-1-hexanol 6.0
Midodrine 5.9
DDMP 5.9
LY 294002 5.9
Phosphoramidon 5.9
Fosinopril 5.9
NaAsO2 5.8
2-ethyl-1-hexanol 5.8
azepane 5.7
Cefmetazole 5.7
ASK 5.7
BCB 5.7
Desflurane 5.7
GRG 5.6
Sufentanil 5.6
Etorphine 5.6
CPP 5.6
Atracurium 5.5
CPP 5.5
2-methylbutanal 5.5
Estramustine 5.5
ATF 5.5
Pipecolic acid 5.5
Anisomycin 5.5
RUB 5.5
Milrinone 5.4
Sodium acetate 5.4
oxalamide 5.4
Tauroursodeoxycholic acid 5.3
Norethisterone 5.3
Diazepam 5.3
Oil Red 5.3
Leflunomide 5.3
Bicalutamide 5.3
Combretastatin 5.3
Herbimycin 5.3
Rilmenidine 5.3
3-methylpentane 5.3
3-methylpyridine 5.3
Isoflurane 5.3
PAP 5.2
Alfentanil 5.2
Sesamol 5.2
Diamminedichloroplatinum 5.2
HAP 5.2
Betulin 5.2
3,4-dihydroxybenzaldehyde 5.2
Nitroprusside 5.2
DMAP 5.2
DMAP 5.1
Phosphoserine 5.1
AET 5.1
Mangostin 5.1
Temazepam 5.1
2-methyl-1-butanol 5.1
Z-Gly 5.1
TPCK 5.1
Digitoxin 5.1
Galangin 5.1
Zeatin 5.1
Tempol 5.1
dADP 5.1
Wortmannin 5.1
Sphingosine 1-phosphate 5.1
PAP 5.1
PAP 5.1
SHM 5.1
4-Hydroxynonenal 5.1
Candesartan 5.0
3-pentanone 5.0
Hyperforin 5.0
PAP 5.0
SAN 5.0
AIR 5.0
8-iso-PGF2alpha 5.0
piperidine-2-carboxylic acid 5.0
DOE 5.0
Polydatin 5.0
GF 109203X 4.9
BAF 4.9
Efron 4.9
Tropisetron 4.9
octanal 4.9
TFF 4.9
Hexobarbital 4.9
octanal 4.9
more...