Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.4.11.18 (
MAP
)
7,412
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Paratuberculosis (Johne's disease) is a chronic,
infectious enteritis
of both domestic and wild ruminants. Unfortunately, the problem of
MAP
infections is not linked only with the health status of animals and potential direct and indirect economic losses in bovine herds (of dairy cattle in particular).
MAP
bacilli present in food of animal origin (milk in particular) are likely to lead to the development of the disease in humans. Fast and effective diagnosis of the disease in animals, especially of its subclinical form, may prevent the transmission of the germ to humans. The study was aimed at analyzing the correlations between the occurance of seropositive and serodoubtful reaction in the ELISA test and the presence of DNA-
MAP
in udder milk. The results suggest that half of the population of animals with positive and doubtful serological responces against John's disease are likely to be a potential source of germ transmission into humans. The fact of detecting DNA-
MAP
in 1/3 of all milk samples points to the likelihood of occurrence of
MAP
bacilli in milk of animals not displaying seropositive or serodoubtful responses.
...
PMID:Analysis of correlations between the occurrence of anti-MAP antibodies in blood serum and the presence of DNA-MAP in milk. 1988 60
