Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.2.1.36 (
hyaluronidase
)
4,606
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
hyaluronidase
4606
collagenase
438
Sep
353
collagen
341
chondroitinase
318
Hyaluronidase
292
ABC
265
CD44
233
proteoglycan
187
Mol
154
neuraminidase
140
glucosamine
126
glycoprotein
108
PH-20
99
spermatozoa
97
SDS
88
fibronectin
79
beta-glucuronidase
71
mucin
66
acid phosphatase
65
albumin
56
alkaline phosphatase
54
phospholipase
53
IgE
51
serum albumin
51
lectin
50
phospholipase A2
48
DNase
47
NMR
46
insulin
46
lipase
46
HYAL1
42
ACR
41
epididymal
40
cytokine
40
HAS2
38
peroxidase
38
lysozyme
37
aggrecan
37
HYAL2
37
ACS
35
elastin
34
phosphodiesterase
32
HAS3
32
type II collagen
32
Hyal-1
31
polypeptide
31
core protein
31
vimentin
31
PEG
30
5'-nucleotidase
30
amylase
30
lactate dehydrogenase
30
ATP
29
chymotrypsin
29
deoxyribonuclease
29
tyrosinase
28
hyaluronan synthase
28
versican
27
mast cell
27
tumor necrosis factor
27
endoplasmic reticulum
26
galactosamine
25
esterase
25
hyaluronan receptor
24
metalloproteinase
24
FSH
24
Trypsin
24
TNF
23
membrane-bound
23
PLA
22
sialidase
22
ESI
22
ferritin
21
acetylcholinesterase
21
Chondroitinase
21
lymphoid
20
PBS
20
cytokeratin
19
hyaluronidase 1
19
more...
Disease
tumor
395
cancer
330
SDS
88
breast cancer
64
tumor growth
62
carcinoma
57
cataract
47
adenocarcinoma
45
metastases
45
arthritis
43
osteoarthritis
41
epididymis
34
rheumatoid arthritis
34
akinesia
34
diabetes
33
melanoma
32
mesothelioma
29
SEM
29
ischemia
29
tumor progression
29
cornea
27
chondrosarcoma
25
atherosclerosis
25
bladder cancer
24
uterus
23
myocardial infarction
23
prostate cancer
22
dehydration
21
meningitis
21
plaque
21
leukemia
21
infertility
20
intraocular pressure
18
malignant mesothelioma
18
immunodeficiency
18
glioma
17
sepsis
17
anaphylaxis
16
lung cancer
16
cold
16
tumorigenesis
16
MCF
16
acute myocardial infarction
15
fibrosarcoma
15
pancreatic cancer
14
asthma
14
glaucoma
14
lymphoma
14
infectious diseases
14
blindness
14
Adhesion
12
myocardial ischemia
12
sepsis
12
pneumonia
11
GSH
11
conjunctiva
11
Haemophilus
11
endocarditis
11
depression
11
colon cancer
10
prolapse
10
mastitis
10
osteosarcoma
10
TEM
9
mucopolysaccharidosis
9
WT1
9
hypertension
9
TEM
9
anemia
9
hepatocellular carcinoma
9
Infection
9
solid tumor
8
bacterial infection
8
vitreous humor
8
squamous cell carcinoma
8
cholera
8
influenza
8
Rous sarcoma
8
colorectal cancer
8
HIV
8
more...
Symptom
anesthesia
106
pain
106
analgesia
24
collapse
20
discomfort
16
discomfort
16
erythema
14
agitation
9
thinning
7
cough
6
functional recovery
6
starvation
5
flushing
5
nausea
5
tremor
5
HSA
5
hypothermia
4
dyspnea
4
paresis
3
dizziness
3
vomiting
3
hypercapnia
3
fatigue
3
cachexia
3
lethargy
3
acidity
3
diarrhea
3
Hudson
3
chest pain
3
skin damage
3
back pain
3
respiratory distress
3
sciatica
3
weakness
3
seizures
3
muscle stiffness
3
ophthalmoplegia
3
catarrh
2
exhaustion
2
Stiffness
2
hypotonia
2
ataxia
2
spasticity
2
nausea and vomiting
2
livedo
2
headache
2
numbness
2
spasm
2
sore throat
1
stomach pain
1
prostatism
1
hyperesthesia
1
Postoperative nausea and vomiting
1
Local reaction
1
low back pain
1
arthralgia
1
ENT
1
pallor
1
Stinging
1
splenomegaly
1
syncope
1
tense
1
asthenia
1
paresthesia
1
hot flashes
1
decreased appetite
1
abdominal pain
1
periorbital edema
1
insomnia
1
acute pain
1
localized edema
1
Crushing
1
muscle rigidity
1
shortness of breath
1
myoclonus
1
colic
1
painful swallowing
1
Mills
1
anorexia
1
POA
1
more...
Drug
Hyaluronidase
319
Hyaluronidase
292
ABC
265
Dermatol
71
lysine
28
Pronase
22
Gel
20
ROS
11
CSF
11
Herceptin
10
Leaf
9
Cardiovasc
9
NAG
9
nitroglycerin
8
ampicillin
7
CaCl2
7
Fraction
7
lactose
7
Histamine
6
Ringer's solution
6
CaCl2
6
citric acid
6
ascorbate
6
CaCl2
6
Fluorescein
5
Paraffin
5
Rituximab
5
MAP
5
Fluorescein
5
balanced salt solution
5
Tannic acid
5
Asthma
5
Albumin
4
Adriamycin
4
Bupivacaine
4
Spectrum
4
caffeine
4
mepivacaine hydrochloride
4
Sodium hyaluronate
4
CAM
4
Areca
4
CLS
4
Vitamin A
4
NADH
4
EE2
3
Retinoic acid
3
vitamin E
3
Asn
3
CEC
3
DNase I
3
Indomethacin
3
Cellulose acetate
3
Biopolymers
3
Prednisolone
3
Ethanol
3
ADR
3
HCG
2
Papain
2
p75
2
Gold sodium thiomalate
2
NaI
2
Marcaine
2
Luteinizing
2
Taxol
2
TAT
2
NaI
2
ZnO
2
NaI
2
IFN-gamma
2
Docetaxel
2
IL-2
2
Sodium thiosulfate
2
NaI
2
ENT
2
Monensin
2
Arfonad
2
Arfonad
2
Butorphanol
2
Xylocaine
2
C3F8
1
more...
Enzyme
hyaluronidase
4606
hyaluronidase
4606
collagenase
446
chondroitinase
328
chondroitinase
321
trypsin
274
neuraminidase
163
phospholipase A2
116
DNase
93
elastase
92
heparinase
84
alkaline phosphatase
77
acid phosphatase
70
beta-glucuronidase
66
chondroitinase AC
65
papain
54
peroxidase
51
hyaluronate lyase
49
hexosaminidase
46
lipase
46
endo-beta-galactosidase
42
acrosin
42
lysozyme
39
chymotrypsin
38
lactate dehydrogenase
37
RNase
36
RNase
36
ACS
35
phosphodiesterase
33
5'-nucleotidase
30
deoxyribonuclease
29
plasmin
29
deoxyribonuclease
29
pepsin
28
tyrosinase
28
Alternating
27
phospholipase C
26
beta-galactosidase
26
acetylcholinesterase
24
mitogen-activated protein kinase
24
sialidase
22
ERK
22
creatine kinase
21
beta-glucosidase
20
thrombin
20
sulfatase
19
catalase
19
lipoxygenase
19
ribonuclease
19
ribonuclease
19
proteinase K
16
ATPase
16
superoxide dismutase
15
beta-glucosidase
15
chondroitin ABC lyase
14
alpha-amylase
13
chondroitinase B
12
luciferase
11
neuropathy target esterase
11
focal adhesion kinase
11
alpha-glucosidase
11
alanine aminotransferase
10
chitinase
9
aspartate aminotransferase
9
kallikrein
9
sorbitol dehydrogenase
9
apyrase
9
phospholipase A1
9
glucose oxidase
8
cathepsin D
8
beta-lactamase
8
adenylate cyclase
8
xanthine oxidase
8
endo-beta-galactosidase
7
endonuclease
7
transglutaminase
7
N-acetylgalactosaminidase
7
glucose-6-phosphate dehydrogenase
6
C5a peptidase
6
alcohol dehydrogenase
6
more...
Compound
hyaluronic acid
1025
sulfate
454
Dec
305
water
191
sodium
180
Clin
170
DNA
164
calcium
127
iron
109
oxygen
107
glucose
105
SDS
93
acetate
92
phosphate
87
galactose
78
GlcNAc
69
ethanol
63
salt
55
PEG
53
GalNAc
50
serine
48
EDTA
46
silver
46
EDTA
46
PEG
44
arginine
43
leucine
42
DEAE
41
ammonium
41
nitrous acid
41
methanol
38
cysteine
37
ACS
35
ACS
35
aldehyde
32
aldehyde
32
lysine
32
Chondroitin sulfate
31
potassium
31
keratan sulfate
30
ATP
29
nitric oxide
29
PAS
29
acetic acid
28
tyrosine
26
acetone
26
HCl
26
Collagen
25
Trypsin
24
DMSO
24
urea
23
cAMP
23
TNF
23
hydrogen
22
chloroform
22
copper
21
Triton X-100
21
CO2
21
DPPH
20
Collagenase
20
formaldehyde
20
MDA
19
nitrogen
18
acrylamide
18
formaldehyde
18
guanidine
18
MgCl2
18
TCA
17
TOF
17
ASA
16
AMP
15
PLA
15
glycerol
15
D-glucuronic acid
15
D-glucosamine
15
zinc
14
Heparin
14
Phe
14
glutamic acid
14
Chondroitin
13
more...