Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.2.1.36 (hyaluronidase)
 4,606 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
hyaluronidase 4606
collagenase 438
Sep 353
collagen 341
chondroitinase 318
Hyaluronidase 292
ABC 265
CD44 233
proteoglycan 187
Mol 154
neuraminidase 140
glucosamine 126
glycoprotein 108
PH-20 99
spermatozoa 97
SDS 88
fibronectin 79
beta-glucuronidase 71
mucin 66
acid phosphatase 65
albumin 56
alkaline phosphatase 54
phospholipase 53
IgE 51
serum albumin 51
lectin 50
phospholipase A2 48
DNase 47
NMR 46
insulin 46
lipase 46
HYAL1 42
ACR 41
cytokine 40
epididymal 40
peroxidase 38
HAS2 38
lysozyme 37
HYAL2 37
aggrecan 37
ACS 35
elastin 34
phosphodiesterase 32
HAS3 32
type II collagen 32
polypeptide 31
vimentin 31
core protein 31
Hyal-1 31
amylase 30
5'-nucleotidase 30
PEG 30
lactate dehydrogenase 30
chymotrypsin 29
ATP 29
deoxyribonuclease 29
hyaluronan synthase 28
tyrosinase 28
mast cell 27
versican 27
tumor necrosis factor 27
endoplasmic reticulum 26
esterase 25
galactosamine 25
hyaluronan receptor 24
Trypsin 24
metalloproteinase 24
FSH 24
TNF 23
membrane-bound 23
PLA 22
sialidase 22
ESI 22
acetylcholinesterase 21
ferritin 21
Chondroitinase 21
lymphoid 20
PBS 20
IL-6 19
cytokeratin 19
hyaluronidase 1 19
trypsin inhibitor 19
carcinoembryonic antigen 18
matrix metalloproteinase 18
lipoxygenase 18
perforin 18
alkaline phosphomonoesterase 18
hyaluronidase 2 18
phosphatase 18
catalase 18
thrombin 18
link protein 18
type I collagen 18
fibrinogen 17
TOF 17
cell adhesion molecule 17
lipopolysaccharide 16
creatine kinase 16
RNase 16
IL-8 16
beta 1 15
HAS1 15
vasopressin 15
axonal 15
keratin 15
vascular endothelial growth factor 15
AMP 15
ATPase 14
Neuraminidase 14
serine protease 14
ECM 14
HYAL-1 13
substance P 13
hyaluronan synthase 2 13
HYAL3 13
glucosidase 13
epidermal growth factor 13
TLR4 13
alpha-amylase 13
hemoglobin 12
prolactin 12
TCH 12
superoxide dismutase 12
CO2 12
Rec 12
p53 12
heparanase 12
Pseudomonas 12
membrane protein 12
sulfatase 12
Pol 12
Sperm adhesion molecule 1 12
ROS 11
tumor necrosis factor alpha 11
cyclooxygenase-2 11
PLA2 11
cardiac muscle 11
gut 11
Hyal-2 11
Gen 11
GSH 11
transferrin 10
Gal 10
platelet-derived growth factor 10
erythroid 10
bradykinin 10
CSF 10
p38 10
anti-elastase 10
She 10
interferon 10
epidermal growth factor receptor 10
VIII 10
MMP-1 10
Mucin 10
MRI 10
myosin 10
peptidase 10
VEGF 9
HYAL4 9
more...
Disease
tumor 395
cancer 330
SDS 88
breast cancer 64
tumor growth 62
carcinoma 57
cataract 47
metastases 45
adenocarcinoma 45
arthritis 43
osteoarthritis 41
akinesia 34
epididymis 34
rheumatoid arthritis 34
diabetes 33
melanoma 32
ischemia 29
SEM 29
tumor progression 29
mesothelioma 29
cornea 27
chondrosarcoma 25
atherosclerosis 25
bladder cancer 24
myocardial infarction 23
uterus 23
prostate cancer 22
dehydration 21
meningitis 21
leukemia 21
plaque 21
infertility 20
intraocular pressure 18
malignant mesothelioma 18
immunodeficiency 18
sepsis 17
glioma 17
MCF 16
cold 16
tumorigenesis 16
lung cancer 16
anaphylaxis 16
acute myocardial infarction 15
fibrosarcoma 15
blindness 14
infectious diseases 14
asthma 14
glaucoma 14
lymphoma 14
pancreatic cancer 14
myocardial ischemia 12
sepsis 12
Adhesion 12
depression 11
pneumonia 11
Haemophilus 11
endocarditis 11
conjunctiva 11
GSH 11
mastitis 10
colon cancer 10
prolapse 10
osteosarcoma 10
Infection 9
WT1 9
hypertension 9
TEM 9
mucopolysaccharidosis 9
hepatocellular carcinoma 9
anemia 9
TEM 9
cholera 8
Rous sarcoma 8
virus infection 8
solid tumor 8
carcinogenesis 8
bacterial infection 8
vitreous humor 8
Blocking 8
colorectal cancer 8
influenza 8
squamous cell carcinoma 8
leeches 8
sclera 8
sarcoma 8
HIV 8
mole 7
IVF 7
mammary tumor 7
coronary occlusion 7
vagina 7
dermatitis 7
PSS 7
type 1 diabetes 7
multiple myeloma 7
herpes simplex 7
thrombocytopenia 7
mole 6
adenoma 6
vitreous detachment 6
ovarian cancer 6
male infertility 6
stroke 6
retinal detachment 6
epithelial ovarian cancer 6
disseminated intravascular coagulation 6
tumor angiogenesis 6
erysipelas 6
CAP 6
periodontitis 6
tuberculosis 6
pharyngitis 6
cystic fibrosis 6
metastatic breast cancer 6
psoriasis 6
aggressiveness 6
aggression 6
Jaagsiekte 5
fasciitis 5
WRN 5
meninges 5
Dermal 5
AIDS 5
streptococcal infection 5
varices 5
cellulitis 5
skin ulcers 5
diplopia 5
chronic obstructive pulmonary disease 5
hydrocephalus 5
Mycobacterium 5
arthropathy 5
gas gangrene 5
scleroderma 5
liposarcoma 5
arachnoiditis 5
toxic shock syndrome 5
type 2 diabetes 5
proptosis 5
glioblastoma 5
brain tumor 5
synovial sarcoma 4
Newcastle disease 4
pulmonary fibrosis 4
chronic bronchitis 4
middle ear 4
Orbit 4
CAM 4
inflammatory bowel disease 4
strabismus 4
lung carcinoma 4
stomatitis 4
Chlamydia 4
ICD 4
malignant fibrous histiocytoma 4
lymphedema 4
West 4
bacteremia 4
skin disease 4
Mycoplasma 4
more...
Symptom
pain 106
anesthesia 106
analgesia 24
collapse 20
discomfort 16
discomfort 16
erythema 14
agitation 9
thinning 7
cough 6
functional recovery 6
nausea 5
starvation 5
HSA 5
flushing 5
tremor 5
dyspnea 4
hypothermia 4
dizziness 3
paresis 3
seizures 3
hypercapnia 3
lethargy 3
skin damage 3
diarrhea 3
cachexia 3
acidity 3
fatigue 3
Hudson 3
chest pain 3
back pain 3
respiratory distress 3
sciatica 3
muscle stiffness 3
weakness 3
vomiting 3
ophthalmoplegia 3
catarrh 2
exhaustion 2
livedo 2
hypotonia 2
ataxia 2
spasticity 2
nausea and vomiting 2
Stiffness 2
headache 2
numbness 2
spasm 2
sore throat 1
stomach pain 1
prostatism 1
hyperesthesia 1
Postoperative nausea and vomiting 1
Local reaction 1
low back pain 1
arthralgia 1
ENT 1
pallor 1
Stinging 1
splenomegaly 1
syncope 1
tense 1
pelvic pain 1
asthenia 1
localized erythema 1
Localized myxedema 1
hot flashes 1
decreased appetite 1
knee pain 1
localized edema 1
Crushing 1
insomnia 1
abdominal pain 1
periorbital edema 1
acute pain 1
Sedation 1
acute abdomen 1
paresthesia 1
flank pain 1
muscle rigidity 1
shortness of breath 1
myoclonus 1
colic 1
painful swallowing 1
Mills 1
anorexia 1
POA 1
apathy 1
Halo 1
oliguria 1
leg pain 1
Welt 1
Drug
Hyaluronidase 319
Hyaluronidase 292
ABC 265
Dermatol 71
lysine 28
Pronase 22
Gel 20
ROS 11
CSF 11
Herceptin 10
NAG 9
Leaf 9
Cardiovasc 9
nitroglycerin 8
Fraction 7
CaCl2 7
lactose 7
ampicillin 7
Histamine 6
citric acid 6
Ringer's solution 6
CaCl2 6
ascorbate 6
CaCl2 6
Fluorescein 5
Rituximab 5
balanced salt solution 5
Tannic acid 5
Fluorescein 5
Paraffin 5
MAP 5
Asthma 5
mepivacaine hydrochloride 4
Vitamin A 4
Bupivacaine 4
Adriamycin 4
Albumin 4
CAM 4
Areca 4
Sodium hyaluronate 4
Spectrum 4
CLS 4
NADH 4
caffeine 4
vitamin E 3
Ethanol 3
CEC 3
Retinoic acid 3
Indomethacin 3
Cellulose acetate 3
Prednisolone 3
EE2 3
Asn 3
DNase I 3
Biopolymers 3
ADR 3
IFN-gamma 2
Luteinizing 2
p75 2
Papain 2
Arfonad 2
TAT 2
NaI 2
Docetaxel 2
NaI 2
NaI 2
Arfonad 2
NaI 2
Marcaine 2
IL-2 2
Sodium thiosulfate 2
Taxol 2
ENT 2
Gold sodium thiomalate 2
HCG 2
Monensin 2
Butorphanol 2
ZnO 2
Xylocaine 2
Fructose 1
Infliximab 1
Vinorelbine 1
ADM 1
Nimesulide 1
Hypaque 1
Indocyanine green 1
Streptokinase 1
Berberine sulfate 1
Bevacizumab 1
Oxacillin 1
Posture 1
Atropine 1
Lacidipine 1
Citric Acid 1
PTC 1
CTM 1
ACT 1
Tocopherol 1
Trifluoperazine 1
Glycerol 1
Adalimumab 1
Navelbine 1
Clonidine 1
G418 1
Meth 1
Salicylate 1
Acemetacin 1
BLM 1
Lacidipine 1
Zephiran chloride 1
Adenosine triphosphate 1
Ulinastatin 1
Methacholine chloride 1
CTM 1
Filgrastim 1
Alliance 1
Dalteparin 1
Galactose 1
Optison 1
Allergen 1
Triprolidine 1
C3F8 1
IFN-beta 1
Scopolamine 1
Estriol 1
Dial 1
Palmitoyl 1
Spectrum 1
Gelatin 1
Kenyan 1
Calcium chloride 1
Glutathione 1
L-tyrosine 1
PCB 1
Serum albumin 1
MEA 1
LMWH 1
Mutagen 1
Citanest 1
FeCl3 1
Phenytoin 1
Botox 1
Nephron 1
Mitomycin-C 1
ICI 1
Angiotensin II 1
Phosphoramidon 1
Aprotinin 1
Trib 1
Hypaque 1
ETA 1
Oxfendazole 1
IPM 1
DM1 1
Chymopapain 1
NBT 1
Antirabies serum 1
Thyroglobulin 1
Hylenex recombinant 1
Monit 1
more...
Enzyme
hyaluronidase 4606
hyaluronidase 4606
collagenase 446
chondroitinase 328
chondroitinase 321
trypsin 274
neuraminidase 163
phospholipase A2 116
DNase 93
elastase 92
heparinase 84
alkaline phosphatase 77
acid phosphatase 70
beta-glucuronidase 66
chondroitinase AC 65
papain 54
peroxidase 51
hyaluronate lyase 49
hexosaminidase 46
lipase 46
endo-beta-galactosidase 42
acrosin 42
lysozyme 39
chymotrypsin 38
lactate dehydrogenase 37
RNase 36
RNase 36
ACS 35
phosphodiesterase 33
5'-nucleotidase 30
plasmin 29
deoxyribonuclease 29
deoxyribonuclease 29
tyrosinase 28
pepsin 28
Alternating 27
phospholipase C 26
beta-galactosidase 26
mitogen-activated protein kinase 24
acetylcholinesterase 24
ERK 22
sialidase 22
creatine kinase 21
thrombin 20
beta-glucosidase 20
ribonuclease 19
catalase 19
lipoxygenase 19
ribonuclease 19
sulfatase 19
proteinase K 16
ATPase 16
beta-glucosidase 15
superoxide dismutase 15
chondroitin ABC lyase 14
alpha-amylase 13
chondroitinase B 12
focal adhesion kinase 11
alpha-glucosidase 11
neuropathy target esterase 11
luciferase 11
alanine aminotransferase 10
kallikrein 9
aspartate aminotransferase 9
chitinase 9
phospholipase A1 9
apyrase 9
sorbitol dehydrogenase 9
cathepsin D 8
adenylate cyclase 8
xanthine oxidase 8
beta-lactamase 8
glucose oxidase 8
N-acetylgalactosaminidase 7
transglutaminase 7
endo-beta-galactosidase 7
endonuclease 7
glucose-6-phosphate dehydrogenase 6
C5a peptidase 6
alcohol dehydrogenase 6
neutrophil elastase 6
ACE 6
reverse transcriptase 6
endoglycosidase H 6
alpha-mannosidase 6
ScpA 6
UDP-glucose dehydrogenase 6
cholinesterase 6
ADPase 6
succinate dehydrogenase 5
protein kinase 5
arylsulfatase 5
phosphofructokinase 5
clostripain 5
subtilisin 5
MMP 5
gamma-glutamyl transpeptidase 5
arginine kinase 5
PI-PLC 5
enolase 4
cellulase 4
nucleotidase 4
iduronate-2-sulfatase 4
aldolase 4
protein kinase C 4
caspase-8 4
tryptase 4
ADH 4
astacin 4
urokinase-type plasminogen activator 4
caspase-3 4
lysin 4
chondro-4-sulfatase 4
heparitinase I 4
PTA 3
succinic dehydrogenase 3
renin 3
P-glycoprotein 3
alanine aminopeptidase 3
beta-xylosidase 3
cytochrome oxidase 3
NAD glycohydrolase 3
chymase 3
ricin 3
alpha-galactosidase 3
cdc2 3
caspase-9 3
deaminase 3
tissue plasminogen activator 3
MEK 3
EC 2.7.7.9 3
glutathione S-transferase 3
endo-alpha-N-acetylgalactosaminidase 3
ficin 3
bromelain 3
phosphoamidase 3
carboxylesterase 3
carbonic anhydrase 3
MMP-3 3
arylsulfatase A 3
PNGase F 3
cathepsin B 3
6-phosphogluconate dehydrogenase 2
6-phosphogluconate dehydrogenase 2
malate dehydrogenase 2
alpha-L-fucosidase 2
TAT 2
choline acetyltransferase 2
sphingomyelinase D 2
topoisomerase 2
cathepsin G 2
adenosine deaminase 2
beta-D-fucosidase 2
venom phosphodiesterase 2
topoisomerase 2
CPR 2
N-acetylglucosamine-6-sulfatase 2
chondroitinsulfatase 2
phosphoinositide 3-kinase 2
glucoamylase 2
more...
Compound
hyaluronic acid 1025
sulfate 454
Dec 305
water 191
sodium 180
Clin 170
DNA 164
calcium 127
iron 109
oxygen 107
glucose 105
SDS 93
acetate 92
phosphate 87
galactose 78
GlcNAc 69
ethanol 63
salt 55
PEG 53
GalNAc 50
serine 48
EDTA 46
silver 46
EDTA 46
PEG 44
arginine 43
leucine 42
nitrous acid 41
ammonium 41
DEAE 41
methanol 38
cysteine 37
ACS 35
ACS 35
aldehyde 32
lysine 32
aldehyde 32
potassium 31
Chondroitin sulfate 31
keratan sulfate 30
ATP 29
nitric oxide 29
PAS 29
acetic acid 28
tyrosine 26
HCl 26
acetone 26
Collagen 25
Trypsin 24
DMSO 24
cAMP 23
TNF 23
urea 23
hydrogen 22
chloroform 22
Triton X-100 21
CO2 21
copper 21
formaldehyde 20
DPPH 20
Collagenase 20
MDA 19
formaldehyde 18
MgCl2 18
acrylamide 18
nitrogen 18
guanidine 18
TCA 17
TOF 17
ASA 16
AMP 15
glycerol 15
D-glucuronic acid 15
PLA 15
D-glucosamine 15
zinc 14
glutamic acid 14
Heparin 14
Phe 14
sodium chloride 13
Chondroitin 13
Cardiol 12
Heparan sulfate 12
GSH 12
GSH 12
retinoic acid 12
methionine 12
TCH 12
Tris 11
alanine 11
bromide 11
Asp 11
Tris 11
threonine 11
hexose 11
TEM 11
glutamate 10
MTT 10
CAM 10
Optimal 10
iodine 10
kaempferol 10
Glucosamine 10
proline 10
Gly 9
Dermatan sulfate 9
PGE2 9
Salt 9
N-acetyl-D-glucosamine 9
UDP 9
Ruthenium red 9
Adriamycin 9
H2O2 8
ethyl acetate 8
His 8
hexuronic acid 8
hexuronic acid 8
hexuronic acid 8
ADR 8
UDP-GlcNAc 8
xylose 8
hexuronic acid 8
Adrenal 7
tryptophan 7
nitrate 7
TCM 7
Ile 7
pyridine 7
glutamine 7
ADP 7
tryptophan 7
DBA 7
NH2 7
ADP 7
ADP 7
tryptophan 7
TCM 7
tryptophan 7
CaCl2 7
HEPES 7
aspartic acid 6
PEI 6
Chondroitin sulfate A 6
Histamine 6
PEI 6
aspartic acid 6
PGE 6
anthracene 6
COS 6
aspartic acid 6
alcohol dehydrogenase 6
2-mercaptoethanol 6
Mg2+ 6
CAP 6
CAP 6
Yellow 6
pentose 6
TRU 6
aspartic acid 6
sulfuric acid 6
more...