Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.2.1.36 (hyaluronidase)
4,606 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The effects of subMICs of penicillin and clindamycin on group A streptococcal products were analyzed. Penicillin caused an increase in the expression of the group carbohydrate for the three strains tested; in contrast, clindamycin inhibited the expression in two strains. The M and T proteins were not affected by the drugs. Clindamycin caused an increase in the hyaluronidase activity and both antimicrobial agents inhibited the activity of streptolysin at 1/2 MIC.
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PMID:Penicillin and clindamycin alter some group A streptococcal products. 268 7