Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.2.1.36 (
hyaluronidase
)
4,606
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Four case reports describing our experience with clinical course and management of paclitaxel extravasation are presented. Local reactions included swelling, mild pain, erythema, induration and hyperpigmentation, but no ulceration. Two patients were treated with cooling only while two further patients received additional
hyaluronidase
injections subcutaneously. The latter patients suffered longer from symptoms.
Local reaction
resolved within two weeks and paclitaxel treatment was continued in 3 of 4 patients without further complications. Overall, paclitaxel extravasation induced only mild soft tissue reaction and cooling should be considered standard treatment.
...
PMID:Clinical course and management of paclitaxel extravasation. 2159 93
