Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.2.1.36 (hyaluronidase)
 4,606 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Ligneous conjunctivitis occurred unilaterally in a 74-year-old man after pterygium excision and only involved the bulbar conjunctiva. Histochemical studies confirmed the presence of mucopolysaccharides in the lesion sensitive to hyaluronidase. The patient was treated successfully with topical hyaluronidase and alpha-chymotrypsin, with no recurrence 20 months after cessation of therapy.
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PMID:Bulbar ligneous conjunctivitis after pterygium removal in an elderly man. 113 97

Ligneous conjunctivitis is a rare chronic conjunctivitis of unknown origin occurring predominantly in young girls. Persistent whitish membranes, 1-2 mm in thickness, are present on the upper and, less frequently, on the lower tarsal conjunctiva. The authors present a 12-year-old girl who is suffering from this disease since the age of four months. The diagnosis was confirmed histologically. Multiple recurrences were observed and were treated either conservatively with hyaluronidase eyedrops or surgically. At the present time, the disease has settled to a tolerable level.
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PMID:Ligneous conjunctivitis. Ten years follow-up. 811 21