Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.2.1.36 (
hyaluronidase
)
4,606
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
A drug-induced collagen-like syndrome was produced in rats by hydralazine administration for 8, 9 and 10 months. The hyaluronic acid content and the
hyaluronidase
activity in liver and spleen were studied. A decrease in the hyaluronic acid amount was accompanied by an enhanced activity of
hyaluronidase
in both tissues. The results provide evidence for metabolic disturbances of glycosaminoglycans in the connective tissue in the
collagen disease
-like syndrome.
...
PMID:Hyaluronic acid content and hyaluronidase activity in liver and spleen of rats with hydralazine-induced collagen-like syndrome. 317 90
