Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.2.1.31 (beta-glucuronidase)
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Human Gene/Protein
KIAA1402 12.0
beta-glucuronidase 11.9
RNA HELICASE 11.0
SKI1 10.0
N-acetyl-beta-glucosaminidase 9.8
GGT3 9.7
arylsulfatase 9.6
arylsulphatase 9.5
GGT4 9.4
HYALP1 9.4
Ribosomal protein S9 9.4
SARL 9.4
ARP8 9.4
Phosphomonoesterase 9.3
GIN1 9.2
CAB-1 9.2
APC2 protein 9.2
60S acidic ribosomal protein P0 9.0
PO42 9.0
glucosidase, alpha 9.0
sulfatase 9.0
alpha-mannosidase 9.0
HK4 8.8
acid DNase 8.8
NIT1 8.7
RAI14 8.7
DGAT1 protein 8.7
beta-mannosidase 8.6
FUCA2 8.6
GTF2H2 8.6
HYAL4 8.6
ASPG 8.6
PCMF 8.6
L13A 8.6
GP110 8.4
ARM1 8.4
MADA 8.4
peptidylprolyl isomerase A 8.4
Hyal-1 8.4
Ligatin 8.3
ugd 8.3
DACT3 8.3
NIT2 8.3
Acid phosphatase 8.2
Hyal-2 8.2
NIR1 8.2
constitutive heat shock protein 70 8.2
GS15 8.2
androgen-regulated protein 8.1
N-acetyl-beta-D-glucosaminidase 8.1
Deoxyribonuclease II 8.1
APC8 8.1
MANB 8.1
RAB2 8.1
photolyase-like 8.1
GGT2 8.0
villin-like 8.0
acid phosphatase 8.0
alkaline phosphodiesterase I 8.0
ACS5 8.0
glucuronyltransferase I 7.9
SKI8 7.9
ARV1 7.9
hypoxanthine phosphoribosyltransferase 1 7.9
APAA 7.9
alpha-galactosidase 7.8
deoxyribonuclease II 7.8
AL4 7.8
CCT1 7.8
alpha-N-acetylglucosaminidase 7.7
HYAL3 7.7
TYKY 7.7
D-glucosyl-N-acylsphingosine glucohydrolase 7.6
MITOCHONDRIAL 7.6
Hexosaminidase 7.6
SIP2 7.6
P69 7.6
ligatin 7.6
NAD-dependent glyceraldehyde-3-phosphate dehydrogenase 7.5
ATP synthase 6 7.5
more...
Disease
IPD1 12.0
MPS VII 11.2
Cribriform carcinoma 11.0
anaplastic osteosarcoma 9.2
MPS IX 8.8
problem with drugs 8.8
Pancolitis 8.7
Gopalan 8.3
ECA3 8.0
dental deposit 7.8
allergic arthritis 7.8
GUD 7.4
lysosomal storage disease 7.3
Aspergillus flavus infection 7.3
unable to remember 7.2
fibroadenosis 7.2
Adrenal suppression 7.1
mucopolysaccharidosis 7.0
ML III 7.0
Biliary sludge 6.9
DIOS 6.9
Mandibuloacral dysplasia 6.8
X-linked hypogammaglobulinemia 6.7
Witts 6.6
Late pregnancy 6.5
Portal hypertensive gastropathy 6.5
C syndrome 6.5
anthracosilicosis 6.5
GCS1 6.4
GS2 6.4
Nonimmune hydrops fetalis 6.4
Argininosuccinic aciduria 6.3
muscle swelling 6.1
benign hypertension 6.1
CACA 6.0
Unicameral bone cyst 6.0
crown gall 5.9
Chronic beryllium disease 5.9
Sanfilippo 5.9
Echinococcus multilocularis infection 5.9
Epithelial dysplasia 5.9
silicotuberculosis 5.8
LINCL 5.8
lymphogranuloma 5.8
infectious meningitis 5.7
CRD1 5.6
leptomeningeal metastases 5.6
DHD 5.6
DHD 5.6
E. coli septicemia 5.5
Infantile neuronal ceroid lipofuscinosis 5.5
HMR 5.5
functioning pituitary adenoma 5.5
Acute necrotizing pancreatitis 5.5
ACS1 5.5
carcinoma of the uterus 5.5
nephroptosis 5.4
CHS 5.4
osteoblastic osteosarcoma 5.3
congenital hemolytic anemia 5.3
EIN 5.2
cholesterolosis 5.2
enzyme deficiency 5.2
hemoglobinemia 5.2
aspermia 5.1
ALS3 5.1
bladder neoplasm 5.0
Thorn 5.0
GS1 4.9
LGL leukemia 4.8
gangliosidosis 4.8
PMT 4.8
laxative abuse 4.8
CNS metastases 4.8
MPS IIIA 4.8
guttate psoriasis 4.7
acute bronchiolitis 4.7
PAF 4.7
CCA1 4.7
immunocytoma 4.7
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Symptom
Food intolerance 6.8
Reticulocytosis 6.4
Severe diarrhea 6.2
physical exhaustion 4.7
blushing 4.5
testicular pain 3.6
Spots 3.2
stigma 3.1
lightheadedness 3.0
abdominal cramps 3.0
swollen joints 3.0
hypoproteinemia 2.9
Gastrointestinal symptoms 2.8
starvation 2.7
hepatosplenomegaly 2.7
joint stiffness 2.0
abnormal gait 1.9
rhinorrhea 1.9
asthenia 1.6
bloating 1.3
hypocapnia 1.3
sneezing 1.1
diarrhea 1.1
splenomegaly 1.1
erythema 0.9
pallor 0.7
tachypnea 0.7
constipation 0.7
Wind 0.7
lethargy 0.5
snoring 0.5
hepatomegaly 0.5
exertional dyspnea 0.3
vertigo 0.2
cyanosis 0.1
myoclonus -0.0
exhaustion -0.1
anorexia -0.1
wheezing -0.2
respiratory distress -0.2
hyperoxia -0.3
ataxia -0.4
cachexia -0.4
hypotonia -0.5
tremor -0.6
myalgia -0.7
anesthesia -0.7
acidity -0.9
weakness -1.2
nausea and vomiting -1.2
insomnia -1.4
thinning -1.4
agitation -1.5
sleepiness -1.6
functional recovery -1.7
analgesia -1.8
collapse -1.8
vomiting -1.9
Welt -2.0
chest pain -2.1
hypothermia -2.1
headache -2.2
angina -2.3
discomfort -2.4
discomfort -2.6
pain -2.7
overweight -2.7
seizures -2.7
abdominal pain -2.9
fatigue -3.6
Drug
Hydrocortisone sodium phosphate 11.0
Verlukast 9.2
Nimetazepam 9.2
Zenarestat 9.0
Klonopin 8.8
Fenclofenac 8.6
Tegison 8.2
Gardenia fruit 7.8
Halofenate 7.8
FML 7.7
Scutellaria root 7.6
Flunixin 7.6
Meclomen 7.4
Pizotifen 7.3
Bisolvon 7.3
Meclomen 7.0
APM 6.8
Denopamine 6.8
Dalacin 6.8
Sodium sulfate 6.7
Hoelen 6.7
Tolfenamic acid 6.6
Dirithromycin 6.5
Clemastine 6.5
Lormetazepam 6.5
Platelet Activating Factor 6.4
Claforan 6.4
Hyaluronidase 6.4
Creosote 6.3
Nabilone 6.3
4-Hydroxytamoxifen 6.2
Potato starch 6.1
Bisacodyl 6.0
Mycophenolic acid 5.9
beta-Galactosidase 5.8
Ceredase 5.8
Flunixin meglumine 5.8
Hyaluronidase 5.8
Gallium nitrate 5.7
Gold sodium thiomalate 5.7
Cibenzoline 5.7
Auranofin 5.6
Dazoxiben 5.6
AC2 5.6
InCl3 5.5
Zinc sulfate 5.5
Zinc sulfate 5.5
Tramal 5.4
NAG 5.3
Cerezyme 5.3
Compound 16 5.3
Perphenazine 5.3
CPT-11 5.3
Neocarzinostatin 5.2
Isoprinosine 5.2
Codeine 5.2
Ulinastatin 5.2
Sesamol 5.2
Codeine 5.1
Tenoxicam 5.1
Aprotinin 5.0
NBT 5.0
Furan 4.9
Dihydrotestosterone 4.9
RBT 4.9
Chlorate 4.8
Acitretin 4.8
Molsidomine 4.8
FLP 4.8
Hypaque 4.7
GVG 4.7
Irinotecan 4.7
Opium 4.6
Hypaque 4.6
Guar gum 4.5
Fenoldopam 4.5
Nedocromil sodium 4.4
Lipidex 4.4
Mitomycin-C 4.3
Flavopiridol 4.3
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Enzyme
beta-glucuronidase 12.0
mannonate dehydrogenase 12.0
mannonate oxidoreductase 12.0
7alpha-dehydroxylase 10.8
beta-glycerophosphatase 10.1
kanamycin kinase 9.8
AtIpk2beta 9.7
cathepsin T 9.7
uronate isomerase 9.7
PhnN 9.4
N-acetylgalactosaminidase 9.2
beta-D-fucosidase 9.2
phosphoamidase 9.1
arylsulfatase 9.0
IDS3 9.0
sulfatase 8.9
alpha-L-fucosidase 8.9
glucarate dehydratase 8.8
IDS2 8.8
alpha-mannosidase 8.8
azoreductase 8.8
mannonate dehydratase 8.7
deuterolysin 8.5
hexosaminidase 8.4
chondro-6-sulfatase 8.4
N-methylcoclaurine 3'-hydroxylase 8.4
alpha-N-acetylglucosaminidase 8.3
beta-glucosidase 8.3
alpha-N-acetylglucosaminyl phosphodiesterase 8.2
alpha-1,3-glucan synthase 8.1
beta-glucosidase 8.1
acid phosphatase 8.0
chondro-4-sulfatase 7.8
cathepsin C 7.7
2',3'-cyclic nucleotide phosphohydrolase 7.6
pancreatic elastase 2 7.6
alpha-glucuronidase 7.6
inositol polyphosphate kinase 7.6
alanine aminopeptidase 7.6
alpha-L-fucosidase 7.6
chondroitin 4-sulfotransferase 7.6
aminopeptidase Y 7.6
beta-xylosidase 7.6
DNase II 7.5
alpha-L-fucosidase 7.5
isopentenyltransferase 7.5
alpha-galactosidase 7.5
GapB 7.4
hygromycin B phosphotransferase 7.4
alpha-L-iduronidase 7.4
N-acetylglucosamine-6-sulfatase 7.4
hyaluronate lyase 7.3
N-acetylglucosaminylphosphotransferase 7.3
AAO3 7.3
trimetaphosphatase 7.3
UDP-glucose dehydrogenase 7.2
cathepsin D 7.2
EC 2.7.7.9 7.1
homospermidine synthase 7.0
BBE 7.0
DGD1 6.9
choline monooxygenase 6.9
beta-galactosidase 6.9
12-oxophytodienoate reductase 6.9
DAP II 6.8
mannanase 6.8
thiogalactoside transacetylase 6.8
cucumisin 6.8
arabinosidase 6.8
1-deoxy-D-xylulose-5-phosphate synthase 6.7
alpha-glucosidase 6.7
PPDK 6.7
UDP-glucuronosyltransferase 6.7
HC-Pro 6.7
arylsulfatase A 6.6
heparitinase I 6.6
PAF acetyltransferase 6.6
galactosylhydroxylysyl glucosyltransferase 6.6
leucine aminopeptidase 6.6
ent-kaurene oxidase 6.6
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Compound
Flazalone 12.0
2-Hydroxyphenacetin 12.0
C7H8O2 12.0
(methylthio)acetonitrile 12.0
C7H8O2 12.0
C7H8O2 12.0
C7H8O2 12.0
C7H8O2 12.0
C7H8O2 12.0
C7H8O2 12.0
C7H8O2 12.0
C7H8O2 12.0
C7H8O2 12.0
C7H8O2 12.0
C7H8O2 12.0
Oleoyl lysophosphatidylcholine 11.0
Clofedanol 11.0
Europium trichloride 11.0
Morfamquat 11.0
Nicotine N-glucuronide 11.0
C7H18N2O 10.4
2-Methylresorcinol 10.4
Thapsigargicin 10.4
4-hydroxy-4-methyl-2,5-cyclohexadien-1-one 10.4
Croconazole 10.4
3-(hydroxymethyl)phenol 10.4
Promazine hydrochloride 10.0
Aniline mustard 10.0
3-Methylcatechol 10.0
C20H24O6 10.0
Bialaphos 9.9
Naphthionic acid 9.7
7,7,7-triphenylheptanoic acid 9.7
7,7,7-triphenylheptanoic acid 9.7
Glucaric acid 9.5
Pronethalol 9.4
Bilirubin monoglucuronide 9.4
7,7,7-triphenylheptanoic acid 9.4
9-chloroacridine 9.4
2,5-Dihydroxyacetophenone 9.4
C10H12O3 9.4
N-Hydroxy-4-aminobiphenyl 9.4
1,2,3,4-tetrahydrophenanthrene 9.3
D-glucaric acid 9.3
2-isopropylnaphthalene 9.2
Bilirubin diglucuronide 9.2
Gulonate 9.2
Darstine 9.2
beta-Glycyrrhetinic acid 9.2
Nitromin 9.0
ergosta-7,22-dien-3-one 9.0
3-Methyl-4-nitrophenol 9.0
Zearalanone 9.0
Glucuronide 8.9
Hymenoxon 8.8
C12H8O4 8.8
2,6-diisopropylnaphthalene 8.8
Naphthol AS-D 8.8
1-naphthyl butyrate 8.7
Gulonate 8.7
Hypolaetin 8.7
Nojirimycin 8.6
6-hydroxy-2-naphthoic acid 8.6
Benzarone 8.6
Tectoridin 8.6
2-amino-1-naphthol 8.4
Ketobemidone 8.4
Ronnel 8.3
Salicyl alcohol 8.3
Pyridoxine hydrochloride 8.3
Acetosyringone 8.3
4-Methylcatechol 8.2
3-methyl-3H-imidazo[4,5-f]quinoline 8.1
CDP-glucose 8.1
Naphthol AS-D 8.0
Cetraxate 8.0
3,4-dimethoxyphenol 8.0
Orotidine 7.9
Norathyriol 7.9
11beta-hydroxyandrosterone 7.9
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