Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.2.1.26 (
invertase
)
4,927
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Anthocyanin accumulation specifically depends on sucrose (Suc) signaling/levels. However, the gene cascades specifically involved in the Suc signaling/level-mediated anthocyanin biosynthetic pathway are still unknown.
Arabidopsis ANGUSTIFOLIA3
(
AN3
), a transcription coactivator, is involved in the regulation of leaf shape and drought tolerance. Recently, an
AN3-CONSTITUTIVE PHOTOMORPHOGENIC 1
gene cascade has been reported to regulate the light signaling-mediated anthocyanin accumulation. Target gene analysis indicates that
AN3
is associated with the
YODA
(
YDA
) promoter, a
mitogen-activated protein kinase kinase kinase
,
in vivo
for inducing anthocyanin accumulation. Indeed, loss-of-function mutants of
YDA
showed significantly increased anthocyanin accumulation.
YDA
mutation can also suppress the decrease in
an3-4
anthocyanin accumulation. Further analysis indicates that the mutations of
AN3
and
YDA
disrupt the normal Suc levels because of the changes of
invertase
activity in mutants of
an3
or
yda
, which in turn induces the alterations of anthocyanin accumulation in mutants of
an3
or
yda
via unknown regulatory mechanisms.
...
PMID:The
Arabidopsis ANGUSTIFOLIA3
-
YODA
Gene Cascade Induces Anthocyanin Accumulation by Regulating Sucrose Levels. 2869 16
