Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.2.1.21 (
beta-glucosidase
)
3,280
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
It has been proposed that the autosomal recessive lamellar ichthyoses may be divided into two subgroups, the erythrodermic (EARLI) and non-erythrodermic (NEARLI) forms. We report measurements of the enzymes
beta-glucosidase
, a recently described phosholipase, a short-chain
carboxylesterase
("butyrase"), and a long-chain
carboxylesterase
("palmitase") in aqueous extracts of scales from patients diagnosed according to clinical and micromorphologic criteria, and show that
beta-glucosidase
and phospholipase tend to be lower in the EARLI group, whereas butyrase is relatively low in the NEARLI group. The internal ratio of either butyrase/glucosidase or butyrase/phospholipase yields a clear separation of the two subgroups, supporting the concept of heterogeneity in this group of diseases.
...
PMID:Enzymatic distinction between two subgroups of autosomal recessive lamellar ichthyosis. 210 61
