Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.2.1.21 (
beta-glucosidase
)
3,280
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Gaucher's disease is a rare disorder characterized by a deficiency of lysosomal
beta-glucosidase
.
Pulmonary hypertension
, the etiology of which is unclear, has been reported to occur in association with Gaucher's disease. We report the use of continuous intravenous epoprostenol (prostacyclin), which has been used to treat other forms of
pulmonary hypertension
, in a patient with
pulmonary hypertension
associated with Gaucher's disease. Although its mechanism of action remains unknown, epoprostenol may be an effective form of therapy for chronic
pulmonary hypertension
due to a variety of conditions, one of which is Gaucher's disease.
...
PMID:Continuous intravenous epoprostenol therapy for pulmonary hypertension in Gaucher's disease. 1085 30
