Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.2.1.20 (
alpha-glucosidase
)
4,237
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Chebulagic acid
, isolated form Terminalia chebula Retz, proved to be a reversible and non-competitive inhibitor of
maltase
with a K(i) value of 6.6 muM. The inhibitory influence of chebulagic acid on the
maltase-glucoamylase
complex was more potent than on the sucrase-isomaltase complex. The magnitude of
alpha-glucosidase
inhibition by chebulagic acid was greatly affected by its origin. These results show a use for chebulagic acid in managing type-2 diabetes.
...
PMID:Chebulagic acid is a potent alpha-glucosidase inhibitor. 1825 69
