Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.2.1.20 (alpha-glucosidase)
4,237 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Leptomeres, the laminated structures consisting of bundles of very fine filaments separated into bands about 260 nm wide by periodic transverse dense lines 20--80 nm wide, were observed frequently in cultured muscle fibers of 8 patients with acid maltase deficiency, 4 with sporadic, adult-onset idiopathic "autophagic" vacuolar myopathy (that is not acid-maltase deficient) and one with abnormal mitochondria, but in only one of greater than 50 other cultures of normal and denervated human muscle. They were also induced abundantly in cultured normal human muscle by exposure to 0.5 mM DNP.
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PMID:Leptomeres in cultured human muscle. 35 7