Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.2.1.17 (
lysozyme
)
21,489
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Bromoacetamide
derivatives having n-alkyl substituents (BrCH2CONH(CH2)nH, 1-n) and carboxyalkyl substituents (BrCH2CONH(CH2)nCOOH, 2-n) react with His-15 in
lysozyme
exclusively at N epsilon 2 at pH 5.5 and 40 degree C. Kinetic studies suggest that
lysozyme
has a small hydrophobic pocket that binds these reagents in the vicinity of His-15.
...
PMID:Nature of the binding site around and reactivity of histidine-15 in lysozyme. 671 10
