Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.2.1.17 (
lysozyme
)
21,489
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Infection of skin injuries by pathogenic microbial strains is generally associated if not treated with a lasting wound bed oxidative stress status, a delay in healing process, and even wound chronicity with several human health complications. The aim of the current study was to explore the antioxidant and antimicrobial potentialities of safflower (
Carthamus tinctorius L.
) extracted oil from seeds by cold pressing which would be beneficial in the management of skin wounds. Antioxidant capacity of the oil was evaluated (scavenging ability against 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and 2,2'-azino-bis 3-ethylbenzothiazoline-6-sulfonic acid (ABTS), and ferric reducing antioxidant power (FRAP)). Total phenolic, total flavonoid, total carotenoid, and total chlorophyll contents were determined. Antimicrobial activities of safflower oil were tested against 10 skin pathogenic microorganisms: 4 bacterial strains (
Escherichia coli
,
Enterobacter cloacae
,
Staphylococcus aureus
, and
Streptococcus agalactiae
), 3 yeast species strains (
Candida albicans
,
Candida parapsilosis
, and
Candida sake
), and 3 fungi species
(Aspergillus niger
,
Penicillium digitatum
, and
Fusarium oxysporum
). A notable antioxidant capacity was demonstrated for the tested oil that exhibited moreover high antibacterial effects by both bacteriostatic and bactericidal pathways including
lysozyme
activity. An antifungal effect was further observed on the spore's germination.
Safflower oil
could be considered as a good natural alternative remedy in the management of skin wounds and their possible microbial infections.
...
PMID:Antioxidant and Antimicrobial Potentials of Seed Oil from
Carthamus tinctorius L.
in the Management of Skin Injuries. 3320 94
