Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: EC:3.2.1.17 (lysozyme)
 21,489 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In the blood of 11 foals and their lactating mothers (Standardbred) diurnal changes in the cortisol level, neutrophil number and lysozyme activity were studied during the first 13 weeks of life. The investigations began when a foal reached 7 days of age and were repeated every two weeks till 13 weeks of age. Blood samples were taken from the jugular vein every 4 hours for one day. Experiments were repeated in two following years. In the first year 6 mares and 6 foals born by these mares were examined, and in the second year--5 of the mares from the first year and the 5 new foals borne by them. All horses were kept and fed under the same conditions. Diurnal rhythm in neutrophil number and lysozyme activity was found neither in foals nor in mares. In the cortisol level a diurnal rhythm was found as early as in the first week of life of a foal as well as in the first week of lactation in mares. The mean diurnal values of cortisol level and lysozyme activity in foal blood were lower by 58% and 22%, respectively, in comparison with mares.
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PMID:Diurnal changes in cortisol level, neutrophil number and lyzozyme activity in foals during the first 13 weeks of life and in their lactating mothers. 145 32

One hundred and twenty patients (64 men and 56 women, aged 19 to 63) with chronic pyelonephritis were subdivided into two groups: a control group of 30 subjects and an experimental one of 90 subjects. Experimental subjects underwent short wave therapy (460 MHz, 50-60 W, for 8-20 minutes) in the lumbar area. Lumbosacral pain disappeared in 87 out of 90, subjects, intercostal pain in 20 out of 28, headache mitigated in 40 out of 53, asthenia was markedly reduced in 49 out of 50. Systolic and diastolic hypertension was reduced, as well as the Kakorski-Addis count in urine. Diurnal diuresis and lysozyme increased, while IgG, IgA and IgM were reduced.
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PMID:[Effects of short-wave therapy in patients with chronic pyelonephritis]. 183 63

The value of various protein and enzyme markers for the assessment of early nephrotoxicity of tobramycin was studied in 18 patients with febrile infection. The renal clearance of creatinine and the excretion of the following protein and enzyme markers were measured on the first and the last day of the 5-8 day treatment period: albumin, N-acetyl-beta-D-glucosaminidase (NAG), beta 2-microglobulin, alpha-amylase, lysozyme and retinol-binding protein (RBP). Diurnal excretions of beta 2-microglobulin, lysozyme and RBP, all markers of tubular dysfunction, were already increased on the first treatment day, compared to similar control patients treated with non-aminoglycoside antibiotics and reference values of our laboratory. The excretion of NAG, an enzyme released from tubular cell lysosomes, was not increased initially, but on the last treatment day it was increased most consistently of all the markers studied. Glomerular filtration rate was halved in 5 of the patients. The results suggest that the initial increase in beta 2-microglobulin, lysozyme and RBP excretion is a result of an early tubular transfer block by tobramycin, whereas the late increase in NAG excretion probably reflects the progress of tubular cell damage during the course of aminoglycoside therapy.
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PMID:Nephrotoxicity of tobramycin. Value of examining various protein and enzyme markers. 187 78