Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.2.1.17 (lysozyme)
 21,489 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The level of total Enterobacterial Enterotoxins of the blood serum, of beta-lysins, lysozyme activity, complement and normal antibodies were studied in 191 patients with acute Flexner dysentery and in 285 patients with acute Sonne dysentery, depending on the period of the disease, its severity, the treatment applied, and the species of the causative agent. The level of the nonspecific humoral immunity factors increased before the treatment and its normalization depended on the treatment applied.
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PMID:[Changes of various factors of nonspecific humoral immunity in acute dysentery]. 79 32

The course of dysentery and the host immune responsiveness were studied in 171 children with acute Flexner's and Sonne dysentery. 67 children were treated with monomycin in combination with lysozyme and 104 children with monomycin alone. It was shown that the recovery period in children treated with monomycin and lysozyme was shorter as compared to that in children treated with monomycin alone. The immunity characteristics in children treated with monomycin were closer to the physiological values. It is concluded that lysozyme potentiates the antibiotic therapy in children with dysentery. It should be used combined with monomycin in the treatment of children irrespective of the age and the disease pattern. The treatment course with the use of monomycin in combination with lysozyme is reduced to 5 days.
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PMID:[Enhanced effectiveness of antibiotic therapy with an exogenous lysozyme in dysentery in children]. 393 8

Course of the disease and some indices of immunity were studied in 100 children with Sonne's and Flexner's dysentery. Parameters of immunity in 32 children (the 1st group) were normal. 68 patients (the 2-nd group) had secondary immune deficiency and leukopenia. Recovery of immunodeficient children in use of antibiotics and prodigiosan was slowed down by 5.2 days as compared to that of children without immunodeficiency. Antibiotics used in combination with lysozyme in patients of the 1st group resulted in restoration of immunological reactivity and recovery in usual terms.
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PMID:[The characteristics of the antibiotic therapy of acute dysentery in an immunodeficiency body state in children with leukopenia]. 806