Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.2.1.15 (
pectinase
)
2,440
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Histone deacetylase (HDAC) performs important functions in plant growth and development, including fruit ripening. As a complex biological process, fruit ripening involves the histone acetylation modification of ripening-associated genes. Histone deacetylase genes (
HDACs
) have been well studied in
Arabidopsis
and rice, but the biological functions of
HDAC
s in papaya are poorly understood. In the present work, three
CpHDACs
, belonging to the
RPD3
/HDA1 subfamily, were identified from papaya and named as
CpHDA1
,
CpHDA2
, and
CpHDA3
.
CpHDA1
and
CpHDA2
were induced by propylene, while
CpHDA3
was propylene-repressed. Moreover, CpHDA3 protein could physically interact with CpERF9 and enhance the transcriptional repression activities of CpERF9 to downstream genes
CpPME1
,
CpPME2
and
CpPG5
. Histone acetylation levels of
CpPME1
and
CpPG5
were increased during fruit ripening. Taken together, these results suggested that CpERF9 recruits CpHDA3 to form a histone deacetylase repressor complex to mediate pectin methylesterase and
polygalacturonase
genes expression during papaya fruit ripening and softening.
...
PMID:Histone Deacetylase CpHDA3 Is Functionally Associated with CpERF9 in Suppression of
CpPME1/2
and
CpPG5
Genes during Papaya Fruit Ripening. 3133 58
