Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.2.1.108 (lactase)
 2,133 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
lactase 2034
brush border 299
alkaline phosphatase 263
sucrase-isomaltase 185
lactase-phlorizin hydrolase 171
Sep 136
gut 126
trehalase 119
aminopeptidase 62
amylase 60
aminopeptidase N 54
Mol 48
Maltase 46
leucine aminopeptidase 44
alpha-glucosidase 38
LCT 36
insulin 34
peptidase 31
polypeptide 30
maltase-glucoamylase 29
dipeptidyl peptidase IV 28
Alkaline phosphatase 27
SDS 27
lipase 27
epidermal growth factor 25
SGLT1 24
alpha-amylase 23
casein 22
LPH 22
intestinal alkaline phosphatase 22
membrane-bound 22
endoplasmic reticulum 20
CD26 20
ATPase 20
gamma-glutamyl transpeptidase 18
acid phosphatase 17
glucose transporter 16
enterokinase 15
glycoprotein 15
glucagon 14
gastrin 14
APA 14
glucosidase 13
superoxide dismutase 12
gamma-glutamyltransferase 12
catalase 12
chymotrypsin 11
IL-6 11
lactate dehydrogenase 11
5'-nucleotidase 11
diamine oxidase 10
membrane protein 10
IgA 10
MCM6 10
IGF-I 10
Glucoamylase 10
microsomal 9
beta-glucuronidase 9
lectin 9
TNF 9
esterase 9
serum albumin 9
occludin 9
ash 9
glucose-6-phosphatase 9
Trehalase 8
B12 8
gamma-glutamyltranspeptidase 8
CFTR 8
collagen 7
ATP 7
alanyl 7
beta-actin 7
GLUT2 7
lymphoid 7
cholecystokinin 7
lysozyme 7
ornithine decarboxylase 7
GSH 7
colon carcinoma 6
glucosamine 6
thyroid hormone 6
hemoglobin 6
tumor necrosis factor 6
GLUT5 6
neuraminidase 6
fur 6
phosphatase 6
AMP 6
ALA 6
thymidine kinase 6
IgE 6
TLR4 6
cytokine 6
albumin 6
secretin 5
lipopolysaccharide 5
adenosine triphosphatase 5
LPS 5
somatostatin 5
glutathione peroxidase 5
insulin-like growth factor-I 5
Na+/glucose cotransporter 5
IBD 5
ZO-1 5
tap 5
villin 5
N-acetyl-beta-glucosaminidase 5
N-acetyl-beta-D-glucosaminidase 5
GTG 5
GATA-4 5
elastin binding protein 4
neurotensin 4
peroxidase 4
EGF 4
RNase 4
Oct-1 4
homeobox 4
LDH 4
dimeric 4
Gen 4
pancreatic lipase 4
DPP IV 4
HDL 4
mTOR 4
adrenocorticotropic hormone 4
Gal 4
beta-endorphin 4
lysosomal acid beta-galactosidase 4
hexokinase 4
housekeeping 4
precursor protein 4
aspartate aminotransferase 4
IL-10 4
prolactin 4
CO2 4
fused 4
Pol 4
growth hormone 4
DSC 3
myeloperoxidase 3
acetylcholinesterase 3
PEG 3
Trypsin 3
HLA 3
IL-1 beta 3
zinc finger 3
DNase I 3
glucose-6-phosphate dehydrogenase 3
alpha-galactosidase 3
parathyroid hormone 3
aldehyde dehydrogenase 3
acid alpha-glucosidase 3
insulin-like growth factor 3
alpha-L-fucosidase 3
glucocerebrosidase 3
L-FABP 3
IL-8 3
SAS 3
MHC 3
more...
Disease
lactose intolerance 210
malabsorption 189
celiac disease 52
malnutrition 48
diabetes 41
cancer 37
irritable bowel syndrome 32
SDS 28
osteoporosis 26
disaccharidase deficiency 24
obesity 23
depression 22
Crohn's disease 22
cystic fibrosis 19
giardiasis 19
inflammatory bowel disease 18
ulcerative colitis 18
enteropathy 17
pancreatic insufficiency 15
enteritis 13
gastrointestinal disease 13
gastroenteritis 12
tumor 11
enzyme deficiency 11
duodenal ulcer 10
SEM 10
acute diarrhea 10
failure to thrive 10
adenocarcinoma 9
steatorrhea 9
ash 9
dyspepsia 9
immaturity 8
dehydration 8
cold 8
hypertension 8
necrotizing enterocolitis 8
GSH 7
infectious diseases 7
asthma 7
West 7
food allergy 7
colorectal cancer 7
Congenital lactase deficiency 6
hyperglycemia 6
Infection 6
gastritis 6
type 2 diabetes 6
colitis 6
anemia 6
HIV 6
carcinoma 6
viral diarrhea 5
cataract 5
ovarian cancer 5
enterocolitis 5
fits 5
multiple sclerosis 5
kwashiorkor 5
cholera 5
iron deficiency 5
short bowel syndrome 5
colon cancer 5
malaria 5
Gaucher disease 5
rheumatoid arthritis 4
sprue 4
carcinogenesis 4
melanoma 4
tuberculosis 4
prostate cancer 4
metabolic syndrome 4
hyperlipidemia 4
gastroesophageal reflux disease 4
lymphoma 4
chronic pancreatitis 4
cardiovascular disease 4
tumor growth 4
atopic dermatitis 4
hypothyroidism 3
hepatic encephalopathy 3
bone disease 3
morbid obesity 3
Secondary lactose intolerance 3
Mycobacterium 3
epithelial ovarian cancer 3
hepatitis 3
immunodeficiency 3
genetic disorder 3
cryptosporidiosis 3
Proteus 3
heart disease 3
Niemann-Pick 3
rhinitis 3
acrodermatitis enteropathica 3
eczema 3
infestation 3
Shigella 3
ischemia 3
bowel obstruction 3
Poland 3
Down syndrome 3
gastric retention 3
encephalopathy 3
Best 3
urticaria 3
ileus 3
autism 3
atherosclerosis 3
Whipple's disease 2
galactosemia 2
eosinophilia 2
sepsis 2
Primary hypolactasia 2
chronic disease 2
hyperinsulinemia 2
Shiga 2
Colon 2
mole 2
atrophic gastritis 2
Mycoplasma 2
Yersinia 2
FAS 2
osteomalacia 2
worms 2
migraine 2
hemochromatosis 2
gastroduodenitis 2
Luminal 2
Crohn's ileitis 2
mole 2
pruritus 2
chronic renal failure 2
gastroschisis 2
protein deficiency 2
stomatitis 2
Colon 2
Hodgkin's disease 2
cytomegalovirus 2
breast cancer 2
sickle cell disease 2
dental calculus 2
vitamin A deficiency 2
tropical sprue 2
graft-versus-host disease 2
Parkinson's disease 2
lymphadenopathy 2
diverticular disease 2
plaque 2
cirrhosis 2
viral enteritis 2
duodenitis 2
intestinal parasites 2
lymphocytosis 2
hyperthyroidism 2
organic disease 2
Jejunum 2
sepsis 2
trisomy 13 2
Edwards 2
more...
Symptom
diarrhea 206
abdominal pain 38
bloating 27
Wind 26
starvation 18
pain 14
colic 8
discomfort 8
discomfort 8
vomiting 7
abdominal discomfort 5
nausea 5
constipation 4
headache 4
anorexia 3
autodigestion 3
anesthesia 3
belching 3
fatigue 3
weakness 2
chronic constipation 2
myalgia 2
stomach pain 2
Food intolerance 2
exertional dyspnea 2
tremor 2
Gastrointestinal symptoms 2
regurgitation 2
acidity 2
bitter taste 1
respiratory distress 1
abdominal cramps 1
hemoptysis 1
syncope 1
Welt 1
hypothermia 1
cough 1
asthenia 1
general problem 1
thinning 1
exhaustion 1
infant diarrhea 1
dizziness 1
distraction 1
DNA marker 1
splenomegaly 1
Mucosal hyperplasia 1
eds 1
ENT 1
overweight 1
cachexia 1
emaciation 1
cerebellar ataxia 1
asterixis 1
orofacial pain 1
microbial colonization 1
functional recovery 1
Infantile colic 1
heartburn 1
hunger 1
acute pain 1
seizures 1
Drug
lactose 666
Lactase 206
Lactose 83
Bifidobacterium 14
Galactose 11
lysine 8
Leaf 7
Fructose 6
Ethanol 5
Gel 4
Nephron 4
Nephron 4
citric acid 4
DNase I 3
beta-Galactosidase 3
CaCl2 2
IL-2 2
Vitamin B 2
Monit 2
Miglustat 2
CaCl2 2
Cimetidine 2
Cimetidine 2
Dermatol 2
ZnO 2
Glucagon 2
Monensin 2
CaCl2 2
Growth hormone 1
caffeine 1
Emodin 1
MRC 1
Maltose 1
NaI 1
L-tyrosine 1
Fragment 1
CDX 1
Albumin 1
Tuareg 1
Tannic acid 1
MgSO4 1
Growth hormone 1
CPT-11 1
NaI 1
HCH 1
GEO 1
NaI 1
NaI 1
IFN-gamma 1
Portal 1
THF 1
Fluorescein 1
ENT 1
CDP 1
Propofol 1
Carbidopa 1
Asn 1
ALA 1
Irinotecan 1
ROS 1
Forskolin 1
MAP 1
Sinemet 1
Fraction 1
Nimesulide 1
Secretin 1
Gluconolactone 1
APM 1
Fluticasone propionate 1
CDX 1
Sodium carbonate 1
Enzyme
lactase 2133
sucrase 727
invertase 662
alpha-glucosidase 564
alkaline phosphatase 264
lactase-phlorizin hydrolase 182
sucrase-isomaltase 179
lactase-phlorizin hydrolase 152
beta-galactosidase 142
trehalase 119
glucoamylase 82
CD13 62
beta-glucosidase 57
gamma-glutamyl transpeptidase 46
trypsin 46
leucine aminopeptidase 43
dipeptidyl peptidase IV 29
ATPase 27
lipase 27
alpha-amylase 24
beta-glucosidase 23
aminopeptidase A 17
acid phosphatase 17
catalase 13
enterokinase 13
cellulase 13
superoxide dismutase 13
pepsin 12
lactate dehydrogenase 12
chymotrypsin 11
5'-nucleotidase 11
papain 10
diamine oxidase 10
glucose-6-phosphatase 9
beta-glucuronidase 9
RNase 8
peroxidase 8
luciferase 8
lysozyme 7
glucose oxidase 7
hexosaminidase 7
RNase 7
ornithine decarboxylase 7
neuraminidase 6
succinate dehydrogenase 6
thymidine kinase 6
elastase 6
aspartate aminotransferase 5
furin 5
MDP 5
glutathione peroxidase 5
inulinase 5
urease 4
alpha-galactosidase 4
urease 4
hexokinase 4
ERK 4
monoamine oxidase 4
endoglycosidase H 4
aldehyde dehydrogenase 3
conjugase 3
xylanase 3
ribonuclease 3
creatine kinase 3
ACE 3
alanine aminotransferase 3
glucokinase 3
ribonuclease 3
acetylcholinesterase 3
aldehyde dehydrogenase 3
aldehyde dehydrogenase 3
chymosin 3
pyruvate kinase 3
aldehyde dehydrogenase 3
glyceraldehyde-3-phosphate dehydrogenase 3
dextranase 3
focal adhesion kinase 3
transglutaminase 3
glucose-6-phosphate dehydrogenase 3
xylanase 3
inulinase 3
glyceraldehyde-3-phosphate dehydrogenase 3
subtilisin 3
glyceraldehyde-3-phosphate dehydrogenase 3
aldehyde dehydrogenase 3
dihydroorotase 2
aspartate transcarbamylase 2
galactokinase 2
alpha-mannosidase 2
tyrosinase 2
galactocerebrosidase 2
phosphodiesterase 2
complex I 2
alpha-L-fucosidase 2
succinic dehydrogenase 2
CPS 2
galactose oxidase 2
adenosine deaminase 2
phosphoenolpyruvate carboxykinase 2
glucocerebrosidase 2
prolinase 2
adenosine deaminase 2
enolase 2
alcohol dehydrogenase 2
NO synthase 2
phosphorylase 2
phosphoenolpyruvate carboxykinase 2
DAP II 2
phospholipase A2 2
caspase-1 2
protein kinase 2
cytochrome oxidase 2
phosphoenolpyruvate carboxykinase 2
RNA polymerase 2
alpha-L-fucosidase 2
CD10 2
uridine kinase 2
glyceraldehyde-3-phosphate dehydrogenase 2
monoacylglycerol acyltransferase 2
pectinase 2
alpha-L-fucosidase 2
tripeptidase 2
glyceraldehyde-3-phosphate dehydrogenase 2
beta-amylase 1
adenylate cyclase 1
beta-lactamase 1
ornithine transcarbamylase 1
proteinase A 1
P-glycoprotein 1
aldolase 1
arginase 1
beta-D-fucosidase 1
beta-1,3-glucanase 1
NQO1 1
estrogen sulfotransferase 1
pullulanase 1
transketolase 1
ketohexokinase 1
deaminase 1
penicillopepsin 1
carbamoylphosphate synthetase 1
diaphorase 1
SPC 1
malate dehydrogenase 1
cathepsin C 1
carboxypeptidase A 1
NADH dehydrogenase 1
allantoicase 1
NADPH oxidase 1
NADPH-diaphorase 1
glucosylceramide synthase 1
argininosuccinate synthetase 1
penicillin acylase 1
acyl-CoA synthetase 1
AST 1
fructokinase 1
carbonic anhydrase 1
PNL 1
pyruvate carboxylase 1
sulfatase 1
more...
Compound
glucose 301
galactose 198
DNA 175
Clin 164
Dec 162
hydrogen 147
sodium 87
Lactose 83
water 81
calcium 79
leucine 42
xylose 34
ethanol 33
SDS 27
sulfate 26
iron 22
methionine 21
acetate 20
alanine 20
phosphate 19
oxygen 19
Phe 19
zinc 18
vitamin D 18
nitrogen 17
potassium 17
Triton X-100 13
salt 13
Sucrose 13
GAL 12
Galactose 11
COS 11
methane 11
lysine 11
hexose 10
proline 10
tryptophan 10
tryptophan 10
hexose 10
tryptophan 10
tryptophan 10
hexose 10
acetic acid 10
hexose 10
Cortisol 10
EDTA 9
TNF 9
copper 9
His 9
acrylamide 9
tyrosine 9
urea 9
butyric acid 8
PEG 8
butyric acid 8
SPM 8
Insulin 8
EDTA 8
GSH 8
GSH 8
glutamine 8
aldehyde 7
ATP 7
phenol 7
Thyroxine 7
Tris 7
butyric acid 7
Tris 7
CO2 7
ammonia 7
cysteine 6
Cortisone 6
Fructose 6
NH2 6
AMP 6
ammonium 6
L-leucine 6
D-galactopyranosyl 5
arginine 5
Trehalose 5
aldehyde 5
phosphorus 5
DEAE 5
glycerol 5
Dexamethasone 5
Pac 4
iodine 4
PEG 4
Leucine 4
Sodium 4
Ile 4
glutamic acid 4
stearic acid 4
silver 4
2-naphthyl 4
alloxan 4
Mg2+ 4
stearic acid 4
stearic acid 4
cAMP 4
Glutamine 4
acetone 4
BBM 3
Bantu 3
Trypsin 3
bromide 3
acetaldehyde 3
barium 3
Thyroid 3
creatinine 3
threonine 3
propionic acid 3
valine 3
adenylate 3
manganese 3
Quercetin 3
propionic acid 3
Lactate 3
aspartic acid 3
formaldehyde 3
beta-D-galactoside 3
formaldehyde 3
Gly 2
ornithine 2
benzaldehyde 2
ornithine 2
benzaldehyde 2
Gossypol 2
benzaldehyde 2
Gossypol 2
benzaldehyde 2
PAM 2
Pentagastrin 2
Mannitol 2
Pyridoxine 2
ornithine 2
Lactulose 2
PAS 2
nitric oxide 2
NAD 2
GM1 2
NAD 2
GMP 2
benzaldehyde 2
ALP 2
benzaldehyde 2
Neu5Ac 2
benzaldehyde 2
N-acetylcysteine 2
Acarbose 2
ornithine 2
CaCl2 2
Sialic acid 2
Monensin 2
benzaldehyde 2
benzaldehyde 2
benzaldehyde 2
benzaldehyde 2
PAM 2
glutamate 2
more...