Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.2.1.108 (
lactase
)
2,133
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Spray-dried ethylcellulose microspheres were used as matrices for the encapsulation of a fungal
lactase
and/or small paramagnetic probes (
Tempol
or Tempo). Their dissolution in water was studied. Kinetics fitted with the model Q = kt(n) of Korsemeyer et al. [Int. J. Pharm. 15 (1983) 25] exhibited a non-Fickian diffusion. The calculated diffusional exponent (n) values were near 0.26 whatever the encapsulated probes. The release rates (k) were only slightly different for paramagnetic probes and
lactase
. This result indicated that the probes' release mechanisms are not diffusion controlled. Other factors such as matrix porosity and probe solubility in the matrix and in water could influence the probes' release rate.
...
PMID:Study of release kinetics of small and high molecular weight substances dispersed into spray-dried ethylcellulose microspheres. 1246 16
