Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.6.4 (chondroitinase)
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Human Gene/Protein
KIAA1402 13.9
chondroitinase 13.9
GALNS 13.4
GALNS protein 13.3
brain link protein-2 12.9
ITI-like protein 12.9
Chondroitinase 12.4
MEA6 12.3
CHST13 11.9
SPACRCAN 11.5
ABC 11.4
ephrin A4 11.3
ChGn 11.3
C4ST-2 11.3
GalNAc4S-6ST 11.0
3B3 11.0
Phosphoinositidase C 10.9
proline/arginine-rich end leucine-rich repeat protein 10.9
neurocan 10.8
PG-Lb 10.8
LGSN 10.8
phosphacan 10.7
PG-M 10.7
syndecan 2 10.7
proteoglycan core protein 10.5
protein tyrosine phosphatase sigma 10.5
HYAL4 10.5
Type XIV collagen 10.5
keratan sulfate proteoglycan 10.4
sulfatase modifying factor 1 10.3
IMPG1 10.3
lysyl oxidase-like 2 10.3
MUC-3 10.2
Neuroglycan C 10.2
chondroitin polymerizing factor 10.1
hyaluronidase 10.1
brevican 10.0
heparan sulfate proteoglycan core protein 10.0
Galactose mutarotase 9.9
Br140 9.9
chondroitin 4-O-sulfotransferase 9.9
cerebroglycan 9.8
tenascin-R 9.8
ARSB 9.7
type XII collagen 9.7
C4ST-1 9.7
CSS3 9.7
chondroitin synthase 9.7
link protein 9.6
PTPRS 9.6
proteoglycan 9.6
beta-1,3-galactosyltransferase 9.5
CL-6 9.5
galactose mutarotase 9.4
SCG1 9.4
CS-2 9.4
80kD 9.3
large aggregating proteoglycan 9.3
versican 9.3
GlcAT-I 9.3
NgR3 9.3
bikunin 9.2
bamacan 9.2
ZG16p 9.2
interphotoreceptor matrix 9.2
core protein 9.1
B-5 9.1
DREG 9.1
biglycan 9.1
NEP1 9.0
galactosamine 9.0
inter-alpha-trypsin inhibitor 9.0
PRELP 9.0
serglycin 9.0
CSGalNAcT-1 8.9
orthodenticle homeobox 2 8.9
IVA 8.9
Syndecan-2 8.9
inter-alpha 8.9
Hyaluronidase 8.8
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Disease
Morquio A syndrome 12.9
Morquio 10.9
MPS IVB 10.0
mucopolysaccharidosis 9.8
Brailsford 9.8
IVA 8.8
metastatic adrenocortical carcinoma 8.8
Sanfilippo 8.1
Myometrium 8.0
Autotomy 7.8
lysosomal storage disease 7.8
cyclitis 7.7
APRT deficiency 7.6
spondyloepiphyseal dysplasia 7.6
HS3 7.5
Mucolipidosis type IV 7.4
chondrosarcoma 7.0
MPS VI 6.8
Hurler 6.5
scleredema 6.5
MSD 6.5
Fibrosarcoma 6.5
corneal dystrophy 6.5
Aspartylglucosaminuria 6.5
Fuchs' endothelial dystrophy 6.5
urticaria pigmentosa 6.5
vitreous detachment 6.2
sclera 6.2
Scheie 6.1
BCD 6.1
CSE 6.1
MPS II 6.1
Retinal degeneration 6.0
degenerative disc disease 6.0
PTP 6.0
mastocytoma 6.0
HP2 6.0
AHL 5.9
disc degeneration 5.9
Dupuytren's disease 5.8
hepatic adenoma 5.7
HCI 5.7
Costello syndrome 5.7
kidney tumor 5.7
MPS I 5.6
MPS VII 5.5
osteoarthropathy 5.5
enzyme deficiency 5.5
Sanfilippo syndrome 5.5
Lowe syndrome 5.4
vitreous humor 5.4
DMC 5.4
Lowe 5.3
CLS 5.2
benign nevi 5.1
quadriparesis 5.0
Proteus 5.0
intellectual impairment 4.9
yaws 4.9
nephrosis 4.9
Perthes disease 4.9
CSB 4.9
chondrodysplasia 4.9
CSB 4.9
proliferative vitreoretinopathy 4.9
CSA 4.8
SDS 4.8
keratoconus 4.7
disabling disease 4.7
Adhesion 4.7
spinal cord compression 4.7
Sheehan's syndrome 4.7
polychondritis 4.7
vitamin C deficiency 4.6
GCT 4.6
spondylitis 4.5
adenocarcinoma of the colon 4.5
cutis laxa 4.5
HEP 4.4
WRN 4.4
more...
Symptom
functional recovery 6.2
bladder pain 5.3
abnormal gait 4.8
chronic back pain 4.4
joint stiffness 3.9
snoring 3.4
sciatica 3.3
tense 2.8
low back pain 2.7
arthralgia 2.1
memory loss 2.1
back pain 1.9
collapse 1.9
hepatosplenomegaly 1.8
ENT 1.6
cachexia 1.5
hepatomegaly 1.4
hypotonia 1.4
flushing 1.3
myalgia 1.3
acidity 1.0
hypothermia 0.9
splenomegaly 0.7
thinning 0.5
agitation 0.4
tremor -0.2
respiratory distress -0.3
starvation -0.7
anesthesia -1.2
weakness -1.3
seizures -1.4
pain -1.5
fatigue -1.7
Drug
ABC 11.4
Hyaluronidase 8.8
Hyaluronidase 8.8
Chymopapain 8.8
Chlorate 8.3
DOXY 8.3
Pronase 8.2
Ioversol 8.0
Cellulose acetate 7.9
Thrombostat 7.8
Vibramycin 7.7
Papain 7.1
Guanidine 6.5
Guanidine 6.5
APM 6.4
Palmitoyl 5.7
Enrofloxacin 5.5
Dalteparin 5.4
Tannic acid 5.4
Rolipram 5.2
Diclofenac sodium 5.2
KGF 5.0
Glutamic acid 4.9
Antithrombin III 4.9
Sinemet 4.9
PDL 4.6
Gel 4.4
Galactose 3.9
NAG 3.9
CEC 3.7
CCL 3.6
Meth 3.5
IPM 3.4
balanced salt solution 3.3
GEO 3.3
p75 3.0
CAM 3.0
Paraffin 2.8
TAT 2.7
lysine 2.7
Fraction 2.6
Fluorescein 2.5
Alanine 2.5
Asn 2.4
Vitamin A 2.4
CaCl2 2.3
CaCl2 2.3
CaCl2 2.3
MRC 2.2
Fluorescein 2.1
DNase I 1.9
G-CSF 1.6
SiO2 1.4
MAP 1.0
Biopolymers 0.9
ENT 0.9
Ethanol 0.7
CSF 0.6
ascorbate 0.4
Dermatol 0.3
lactose -0.1
ampicillin -0.1
Leaf -0.5
IFN-gamma -0.9
Enzyme
chondroitinase 13.9
chondroitinase 13.7
chondro-6-sulfatase 12.9
chondroitinase AC 12.6
chondro-4-sulfatase 12.6
chondroitinase B 12.3
hyaluronidase 12.2
heparitinase I 12.1
galactose-6-sulfatase 11.6
endo-beta-galactosidase 11.4
GalNAc4S-6ST 11.2
heparinase 11.2
chondroitin ABC lyase 10.4
hyaluronidase 10.1
endo-beta-galactosidase 9.8
EC 2.4.2.26 9.5
chondroitin synthase 9.5
endo-alpha-N-acetylgalactosaminidase 9.3
chymopapain 8.8
clostripain 8.8
chymopapain 8.8
galactosyltransferase I 8.8
chondroitin 6-sulfotransferase 8.6
maltose phosphorylase 8.3
phosphatidylinositol phospholipase C 8.3
iduronate-2-sulfatase 8.0
aggrecanase-1 8.0
hyaluronate lyase 8.0
sulfatase 7.5
PNGase F 7.3
penicillin binding protein 7.2
mutarotase 7.2
papain 7.0
glycoprotease 7.0
sialidase 6.6
neuraminidase 6.6
pyroglutamate aminopeptidase 6.5
TSR 6.4
neutrophil collagenase 6.4
methionine synthase reductase 6.3
deoxyribonuclease 6.2
collagenase 6.2
deoxyribonuclease 6.2
lysophospholipase D 6.1
endo-N 6.0
endoglycosidase H 5.9
PI-PLC 5.8
arylsulfatase A 5.7
DNase 5.6
proteinase K 5.5
trypsin 5.5
ATP sulfurylase 5.5
nucleotide pyrophosphatase 5.4
cathepsin C 5.3
arylsulfatase 5.3
elastase 5.2
galactocerebrosidase 5.2
endoproteinase Glu-C 5.2
DNase II 5.2
beta-amylase 5.1
chymase 5.1
plasmin 5.0
lysyl endopeptidase 5.0
p80 4.8
cathepsin G 4.7
chymotrypsin 4.7
lysyl oxidase 4.6
adenine phosphoribosyltransferase 4.5
pepsin 4.4
alpha-L-fucosidase 4.4
sphingosine kinase 4.4
hexosaminidase 4.1
beta-secretase 4.1
proprotein convertase 3.8
tissue plasminogen activator 3.8
MMP-3 3.8
Thy1 3.7
beta-galactosidase 3.7
CPS 3.6
thrombin 3.6
more...
Compound
N-Acetylgalactosamine 6-sulfate 13.9
Chondroitin 6-sulfate 11.3
Chondroitin sulfate 11.0
Dermatan sulfate 10.8
keratan sulfate 10.7
Chondroitin sulfate A 10.7
GalNAc4S 10.7
Dermatan sulfate 10.6
L-Iduronic acid 10.6
Chondroitin 10.4
hexuronic acid 9.8
hexuronic acid 9.7
nitrous acid 9.7
hexuronic acid 9.7
hexuronic acid 9.7
iduronate 9.7
D-glucuronic acid 9.2
Chlorate 8.6
Sodium chlorate 8.6
TCH 8.6
Heparan sulfate 8.5
Chlorate 8.2
Stains-all 8.2
Hydroxylysine 8.2
UDP-N-acetylgalactosamine 8.0
H-69 8.0
hyaluronic acid 8.0
Azure A 7.8
trifluoromethanesulfonic acid 7.8
GalNAc 7.8
trifluoromethanesulfonic acid 7.7
Paraformaldehyde 7.6
Bromophenol Blue 7.5
Ruthenium red 7.5
Sodium deoxycholate 7.3
Paraformaldehyde 7.2
sulfate 7.2
Collagenase 7.1
Polybrene 7.1
Toluidine blue 7.0
Coomassie Blue 7.0
guanidine 6.7
2-aminobenzoic acid 6.7
2-aminobenzoic acid 6.7
Ruthenium 6.4
Ruthenium 6.4
Nitrite 6.4
DEAE 6.3
Silver, 6.2
2-aminobenzamide 6.2
NH4OH 6.2
ACI 6.1
Heparin 6.0
PAPS 6.0
Cyanine 5.9
SAN 5.9
SSH 5.8
Cyanogen bromide 5.8
6-aminohexanoic acid 5.8
6-aminohexanoic acid 5.8
Trimethylamine N-oxide 5.8
Magnesium sulfate 5.7
TEP 5.7
CAA 5.5
Puromycin 5.5
MgCl2 5.5
D-glucuronate 5.5
APS 5.5
1,4-butanediol 5.4
Agarose 5.4
HCI 5.3
Keloid 5.3
4-hydroxyproline 5.2
4-hydroxyproline 5.2
4-hydroxyproline 5.2
4-hydroxyproline 5.2
4-hydroxyproline 5.2
4-hydroxyproline 5.1
Suramin 5.1
T10 5.0
more...