Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.6.12 (chondroitinase)
 2,183 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
chondroitinase 1909
ABC 1483
proteoglycan 583
hyaluronidase 321
collagen 236
arylsulfatase B 233
core protein 188
Sep 138
MPS VI 123
axonal 111
glucosamine 104
Mol 95
SDS 90
collagenase 84
neuraminidase 79
fibronectin 74
Chondroitinase 73
glycoprotein 69
aggrecan 67
sulfatase 63
decorin 59
arylsulfatase A 53
heparan sulfate proteoglycan 52
versican 47
galactosamine 44
polypeptide 42
biglycan 40
ARSB 40
NMR 39
lectin 39
neurocan 32
arylsulfatase 31
syndecan 30
link protein 30
CD44 27
mast cell 26
thrombin 26
Arylsulfatase B 26
type I collagen 25
phosphacan 24
beta 1 24
mucin 23
alkaline phosphatase 21
proteoglycan core protein 21
Gal 20
perlecan 20
ASB 19
ferritin 19
peroxidase 18
type II collagen 17
beta-glucuronidase 17
parvalbumin 17
elastin 16
pleiotrophin 16
sialidase 16
NG2 15
antithrombin 14
3B3 14
chymotrypsin 13
chemokine 13
tenascin-R 13
brevican 13
N-glycanase 12
phosphatase 12
HNK-1 12
Hyaluronidase 12
acid phosphatase 11
fibrinogen 11
DNase 11
Arylsulfatase A 11
inter-alpha-trypsin inhibitor 11
Midkine 11
heparin cofactor II 11
cell adhesion molecule 11
Nogo 11
Neuraminidase 11
cytokine 11
epidermal growth factor 11
interphotoreceptor matrix 10
olfactory 10
threonine 10
heparanase 10
fused 10
keratan sulfate proteoglycan 10
bikunin 10
midkine 10
Glypican-3 10
thrombospondin 10
brain-derived neurotrophic factor 10
trypsin inhibitor 10
delta 4 10
insulin 9
IgE 9
FGF 9
PG-M 9
steroid sulfatase 9
membrane-bound 9
CA1 9
endoplasmic reticulum 9
plasminogen 9
protein tyrosine phosphatase 8
Aggrecan 8
ECM 8
EGF 8
A-2 8
serum albumin 8
glypican 8
tumor necrosis factor 8
antithrombin III 8
microsomal 8
PBS 8
lymphoid 8
Rho 8
tenascin 7
serglycin 7
membrane protein 7
IL-8 7
esterase 7
nerve growth factor 7
albumin 7
Rec 7
MRI 7
PDGF 7
TCH 7
sulfotransferase 7
colon carcinoma 7
adhesion molecule 7
lipase 7
alpha-mannosidase 6
Trypsin 6
fibromodulin 6
cell surface receptor 6
thrombomodulin 6
hepatocyte growth factor 6
neurotrophin 6
glial cell line-derived neurotrophic factor 6
Platelet factor 4 6
ESI 6
IL-3 6
heavy chain 6
neural cell adhesion molecule 6
LDL receptor 6
TGF-beta 6
metalloproteinase 6
protein C 6
B-5 6
protein-tyrosine phosphatase 6
alpha-L-iduronidase 6
galectin-3 6
Pseudomonas 6
tissue plasminogen activator 6
lipoprotein lipase 5
lipopolysaccharide 5
T10 5
AMBP 5
cage 5
tenascin-C 5
thymus 5
ATP 5
tyrosine hydroxylase 5
more...
Disease
MPS VI 125
SDS 90
tumor 60
cancer 47
chondrosarcoma 35
cornea 29
lysosomal storage disease 27
osteoarthritis 26
mucopolysaccharidosis 26
atherosclerosis 20
Alzheimer's disease 16
Proteus 16
sclera 15
MSD 13
melanoma 13
carcinoma 13
metachromatic leukodystrophy 12
diabetes 12
stroke 11
adenocarcinoma 10
Adhesion 10
cystic fibrosis 10
glaucoma 9
arthritis 9
cholera 9
hepatocellular carcinoma 8
breast cancer 8
leukemia 8
anaphylaxis 8
Hurler 8
glioma 8
mastocytoma 7
PSS 7
disc degeneration 7
Sanfilippo 6
plaque 6
MPS I 6
metastases 6
depression 6
hypertension 6
arthropathy 6
Morquio 6
neuroblastoma 6
ischemia 6
cold 5
SEM 5
Parkinson's disease 5
dysplasia 5
uterus 5
HIV 5
Evans 5
spinal cord compression 5
myelopathy 5
malaria 4
pheochromocytoma 4
corneal dystrophy 4
colon cancer 4
degenerative disc disease 4
epilepsy 4
intraocular pressure 4
prostate cancer 4
hypercholesterolemia 4
sarcoma 4
lung cancer 4
heart failure 4
proteinuria 4
PTP 4
chronic myeloid leukemia 4
periodontitis 4
metabolic disorder 4
mole 4
squamous cell carcinoma 4
PDB 3
ichthyosis 3
thrombocytopenia 3
CSE 3
carcinogenesis 3
dehydration 3
polyarthritis 3
AIDS 3
mole 3
Melanoma 3
TEM 3
mastocytosis 3
sepsis 3
schizophrenia 3
acute promyelocytic leukemia 3
HCI 3
keratoconus 3
CSA 3
hydrocephalus 3
ocular hypertension 3
lung carcinoma 3
rheumatoid arthritis 3
nephrosis 3
MPS II 3
vitreous humor 3
CAM 3
mental retardation 3
WRN 3
CEM 3
Placenta 3
MCF 3
periodontal disease 3
epidermolysis bullosa 3
mental retardation 3
virus infection 3
osteosarcoma 3
SRS 3
TEM 3
fibrosarcoma 3
asthma 3
ichthyosis 3
myocardial infarction 3
lymphoma 3
cognitive impairment 3
external ear 2
astrocytoma 2
epithelial ovarian cancer 2
Dupuytren's disease 2
Frey 2
malnutrition 2
Lowe syndrome 2
MLS 2
adenoma 2
hyperglycemia 2
IVA 2
proliferative vitreoretinopathy 2
myeloid leukemia 2
urticaria pigmentosa 2
pancreatic cancer 2
cataract 2
conjunctiva 2
schwannoma 2
Schistosoma mansoni 2
herpes simplex 2
colorectal cancer 2
lung metastases 2
HS3 2
genetic disorder 2
kidney tumor 2
Brown 2
tumor growth 2
meninges 2
myopia 2
Still 2
osteoarthropathy 2
pulmonary fibrosis 2
tumor progression 2
multiple sclerosis 2
pemphigoid 2
nasal allergy 2
otitis media 2
cardiomyopathy 2
pertussis 2
uterine cervix 2
tuberculosis 2
APC 2
choriocarcinoma 2
blindness 2
more...
Symptom
functional recovery 63
pain 7
collapse 7
hepatosplenomegaly 5
low back pain 4
hepatomegaly 3
back pain 3
anesthesia 2
hypotonia 2
hypothermia 2
joint stiffness 2
seizures 2
acidity 2
cachexia 1
erythema 1
myalgia 1
fatigue 1
chest pain 1
regurgitation 1
dry eye 1
splenomegaly 1
nausea 1
bladder pain 1
arthralgia 1
chronic back pain 1
starvation 1
sciatica 1
headache 1
angina 1
neck stiffness 1
thinning 1
memory loss 1
vomiting 1
flushing 1
abnormal gait 1
tremor 1
Drug
ABC 1483
lysine 25
Pronase 25
Gel 23
Dermatol 22
Hyaluronidase 13
Hyaluronidase 12
Papain 5
Cellulose acetate 4
Asn 4
ascorbate 4
Chlorate 3
CSF 3
CAM 3
Galsulfase 2
NAG 2
p75 2
MAP 2
Guanidine 2
Guanidine 2
CaCl2 2
Chymopapain 2
CaCl2 2
Ethanol 2
CaCl2 2
DNase I 2
IPM 1
Dalteparin 1
Glutamic acid 1
Orphan 1
Fluorescein 1
Thrombostat 1
Tannic acid 1
Alanine 1
IL-2 1
DOXY 1
IFN-gamma 1
TAT 1
Antithrombin III 1
Enrofloxacin 1
PDL 1
Diclofenac sodium 1
CCL 1
Vitamin A 1
GEO 1
Angiotensin II 1
Fraction 1
balanced salt solution 1
Theophylline 1
Fluorescein 1
Palmitoyl 1
ampicillin 1
Leaf 1
SiO2 1
Paraffin 1
APM 1
G-CSF 1
KGF 1
Ioversol 1
Rolipram 1
Meth 1
Vibramycin 1
CEC 1
Sinemet 1
MRC 1
Enzyme
chondroitinase 2183
chondroitinase 1912
hyaluronidase 1912
hyaluronidase 321
sulfatase 253
heparinase 194
trypsin 122
chondroitinase AC 122
neuraminidase 93
endo-beta-galactosidase 86
collagenase 86
arylsulfatase A 53
papain 53
arylsulfatase 42
thrombin 26
peroxidase 25
heparitinase I 23
alkaline phosphatase 22
chondroitinase B 20
elastase 20
DNase 18
chymotrypsin 18
endo-beta-galactosidase 18
plasmin 17
chondroitin ABC lyase 17
sialidase 16
PNGase F 15
beta-glucuronidase 14
phospholipase C 13
beta-galactosidase 13
hexosaminidase 13
proteinase K 13
pepsin 12
chymopapain 12
acid phosphatase 12
chymopapain 12
endoglycosidase H 11
iduronate-2-sulfatase 11
tissue plasminogen activator 10
ERK 9
protein kinase 9
beta-lactamase 8
mitogen-activated protein kinase 7
clostripain 7
alpha-mannosidase 7
alpha-L-iduronidase 7
APC 7
lipase 7
chondro-4-sulfatase 7
chondro-6-sulfatase 6
N-acetylglucosamine-6-sulfatase 6
urokinase-type plasminogen activator 6
protein kinase C 6
lipoprotein lipase 5
reverse transcriptase 5
tyrosine hydroxylase 5
AMPK 5
hyaluronate lyase 5
alpha-amylase 4
phosphodiesterase 4
phospholipase D 4
GalNAc4S-6ST 4
diamine oxidase 4
chymase 4
lysozyme 4
deoxyribonuclease 4
deoxyribonuclease 4
thromboplastin 4
galactose-6-sulfatase 4
focal adhesion kinase 4
cathepsin D 4
RNase 4
RNase 4
penicillin binding protein 3
transglutaminase 3
neutrophil elastase 3
subtilisin 3
endo-alpha-N-acetylgalactosaminidase 3
glutathione S-transferase 3
MMP-3 3
nucleotide pyrophosphatase 2
cathepsin G 2
lysyl oxidase 2
galactocerebrosidase 2
chitinase 2
chondroitinsulfatase 2
galactosyltransferase I 2
caspase-3 2
alpha-L-fucosidase 2
beta-glucosidase 2
gamma-glutamyl transpeptidase 2
alpha-galactosidase 2
adenylate cyclase 2
calcineurin 2
phosphatidylinositol phospholipase C 2
ACS 2
superoxide dismutase 2
glyceraldehyde-3-phosphate dehydrogenase 2
tryptase 2
alpha-glucosidase 2
beta-glucosidase 2
acetylcholinesterase 2
RNA polymerase 2
luciferase 2
ribonuclease 2
chondroitin synthase 2
furin 2
ribonuclease 2
PI-PLC 2
transcriptase 2
phospholipase A2 2
lactate dehydrogenase 2
lysophospholipase D 1
beta-D-fucosidase 1
MMP 1
mutarotase 1
TSR 1
xanthine oxidase 1
ricin 1
alpha-N-acetylglucosaminyl phosphodiesterase 1
endoproteinase Glu-C 1
glyceraldehyde-3-phosphate dehydrogenase 1
histidine decarboxylase 1
MAT 1
neutrophil collagenase 1
alpha-L-fucosidase 1
matrix metalloproteinase 9 1
CaMKII 1
PARP 1
glyceraldehyde-3-phosphate dehydrogenase 1
chondroitin 4-sulfotransferase 1
phosphatidylinositol 3-kinase 1
EC 2.4.2.26 1
GSK 1
site-1 protease 1
cathepsin K 1
endo-N 1
proteasome 1
aspartate transcarbamylase 1
Thy1 1
leucine aminopeptidase 1
Alternating 1
sphingosine kinase 1
asparaginase 1
ATPase 1
glyceraldehyde-3-phosphate dehydrogenase 1
dopamine beta-hydroxylase 1
chondroitin 6-sulfotransferase 1
lysyl endopeptidase 1
MAT 1
kinesin 1
beta-amylase 1
cytochrome oxidase 1
NADPH-diaphorase 1
STR 1
proprotein convertase 1
PTA 1
TAT 1
CPN 1
beta-secretase 1
more...
Compound
sulfate 1125
hyaluronic acid 199
Dec 171
sodium 138
GalNAc 111
Chondroitin sulfate 106
nitrous acid 101
keratan sulfate 98
SDS 94
DEAE 86
acetate 80
galactose 78
guanidine 63
Clin 62
DNA 61
phosphate 60
HCl 55
serine 50
calcium 50
water 43
iron 41
leucine 38
salt 36
ethanol 33
lysine 32
arginine 31
silver 30
Dermatan sulfate 29
Chondroitin 29
Heparin 29
Heparan sulfate 28
urea 26
GlcNAc 26
EDTA 23
EDTA 22
Asp 22
Dermatan sulfate 22
D-glucuronic acid 22
methionine 21
alanine 21
threonine 18
proline 18
tyrosine 17
cAMP 17
Triton X-100 16
glucose 16
hexuronic acid 15
hexuronic acid 15
Gly 15
hexuronic acid 15
hexuronic acid 15
NH2 15
Collagen 15
cysteine 14
oxygen 14
MgCl2 14
aldehyde 14
aldehyde 14
ammonium 14
Nitrite 13
iduronate 13
glutamic acid 13
His 12
methanol 12
xylose 11
sulfuric acid 11
hydrogen 11
aspartic acid 9
Collagenase 9
Tris 9
Phe 9
aspartic acid 9
ASA 9
aspartic acid 9
Tris 9
acrylamide 9
chloroform 9
aspartic acid 9
nitric oxide 8
PEG 8
acetonitrile 7
fluorine 7
Ile 7
asparagine 7
TCA 7
TCH 7
sodium chloride 7
COS 7
hexose 6
Ruthenium 6
PAS 6
C-3 6
Retinal 6
Chondroitin sulfate A 6
barium 6
Trypsin 6
glutamate 6
bromide 6
Ruthenium red 6
Ruthenium 6
acetone 6
APS 6
GABA 5
trifluoromethanesulfonic acid 5
Toluidine blue 5
GABA 5
UDP 5
octyl 5
zinc 5
trifluoromethanesulfonic acid 5
T10 5
glucose-6-phosphate 5
octyl 5
glutamine 5
ATP 5
PNA 5
octyl 5
ACI 5
valine 4
phosphoric acid 4
Agarose 4
THP 4
Coomassie Blue 4
Chondroitin 6-sulfate 4
PEG 4
TNF 4
MDA 4
hexose 4
GalNAc4S 4
AMP 4
retinoic acid 4
hexose 4
TEM 4
hexose 4
THP 4
creatinine 4
ornithine 3
formic acid 3
UDP-N-acetylgalactosamine 3
ornithine 3
UDP-N-acetylgalactosamine 4-sulfate 3
Pac 3
formic acid 3
CBS 3
HCI 3
formic acid 3
formic acid 3
ornithine 3
formic acid 3
formic acid 3
oxalate 3
2-mercaptoethanol 3
CO2 3
ornithine 3
pyridine 3
Chlorate 3
formic acid 3
Sucrose 3
silicon 3
5-HT 3
more...