Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.6.1 (sulfatase)
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Human Gene/Protein
Gal-NAc6S 13.3
heat shock 70kDa protein 2 13.3
MPS4A 13.3
arylsulfatase A 13.3
ARSK 13.3
arylsulfatase 13.3
sulfatase 13.3
steroid sulfatase (STS) 13.1
arylsulfatase B 13.0
SUMF1 protein 12.9
Arylsulfatase G 12.9
Sulfatase modifying factor 1 12.7
Arylsulfatase B 12.6
ARSB 12.5
sulfatase modifying factor 1 12.5
STS protein 12.3
sulfatase modifying factor 2 12.3
estrone sulfatase 12.3
ARSJ 12.3
cerebroside sulfate activator protein 12.3
GALNS protein 12.3
SUMF1 12.2
ARSC 12.2
Arylsulfatase A 12.1
N-acetylglucosamine-6-sulfatase 12.1
MPS VI 11.9
steroid sulfatase 11.9
17beta-HSD type 12 11.7
RYSR 11.7
ARSA 11.7
Xg blood group antigen 11.7
sulfatase 2 11.3
Tyramine oxidase 11.3
arylsulfatase K 11.3
GALNS 11.3
arylsulfatase E 11.2
ARSI 11.0
BRAG 10.7
GALN 10.7
3-OST-5 10.7
more...
Disease
MPS VIII 13.3
Deficiency of arylsulfatase 13.0
MPS VI 11.7
MPS IIID 11.6
metachromatic leukodystrophy 11.5
torsion spasm 11.0
Morquio A syndrome 10.7
Rud syndrome 10.4
MPS IIIA 10.0
Morquio 9.7
MSD 9.7
Sanfilippo 9.6
lysosomal storage disease 9.4
mucopolysaccharidosis 9.3
Brailsford 9.1
Sanfilippo syndrome 9.1
CDPX1 9.0
MPS II 9.0
sphingolipidosis 8.9
ML III 8.8
hebephrenia 8.5
Mucolipidosis 8.5
STS 8.4
MPS IIIC 8.4
MPS IVB 8.3
warfarin embryopathy 8.2
Segmental demyelination 8.1
49,XXXXY syndrome 8.1
Ichthyosis vulgaris 8.0
Chondrodysplasia punctata 7.9
ichthyosis 7.8
C syndrome 7.8
inv(X) 7.7
ichthyosis 7.7
Rokitansky-Aschoff sinuses 7.6
HSAN1 7.5
enzyme deficiency 7.4
GM1 gangliosidosis 7.4
Hurler 7.3
XX males 7.2
more...
Symptom
Macula 6.4
scaly skin 5.9
Neurologic symptoms 5.8
disturbed balance 5.4
joint stiffness 5.2
ataxic gait 5.2
meningism 4.9
hepatosplenomegaly 4.9
Spots 4.5
lightheadedness 4.3
hypotonia 4.1
neck stiffness 4.0
anosmia 3.7
cerebellar ataxia 3.5
spasticity 3.4
hepatomegaly 3.4
Stiffness 3.3
dry skin 3.3
microbial colonization 3.2
abnormal gait 3.1
muscle stiffness 3.0
masculinization 3.0
chronic constipation 3.0
myoclonus 2.8
starvation 2.7
incoordination 2.5
memory loss 2.5
spasm 2.4
dysarthria 2.4
lethargy 2.4
twitching 2.3
skin irritation 2.2
ataxia 2.1
dry eye 1.9
asthenia 1.9
paraparesis 1.8
dystonia 1.8
cachexia 1.8
HSA 1.7
colic 1.6
more...
Drug
Galsulfase 12.3
Sodium picosulfate 9.7
Sulfamide 9.2
Equilenin 9.1
Gardenia fruit 9.1
Calcium citrate 8.7
Pizotifen 8.6
Tibolone 8.3
Nabilone 7.6
Sodium ascorbate 7.5
NYS 7.5
Polysorbate 20 7.4
Chloramine T 7.4
Dienogest 7.0
Micafungin 6.6
Tramal 6.6
Perphenazine 6.6
beta-Galactosidase 6.5
Trilostane 6.5
Estriol 6.5
Sesamol 6.4
Poudre 6.4
Protamine sulfate 6.3
Compound 15 6.3
Cellulose acetate 6.2
Estrogens 5.6
Rutin 5.5
Hyaluronidase 5.5
Hyaluronidase 5.3
niacin 5.2
Pregnenolone 5.1
Premarin 5.0
Myricetin 5.0
Fondaparinux 4.9
DHT 4.8
TRM 4.7
Tannic acid 4.7
DHT 4.7
EE2 4.7
Zoledronic acid 4.6
more...
Enzyme
sulfatase 13.3
choline-sulfatase 13.3
arylsulfatase A 13.3
galactose-6-sulfatase 13.0
arylsulfatase 12.9
N-acetylglucosamine-6-sulfatase 12.2
chondro-6-sulfatase 12.0
3-KSR 11.7
glucuronate-2-sulfatase 11.7
chondro-4-sulfatase 11.1
phosphoglycerol transferase 11.1
EC 5.4.99.15 11.0
N-sulfoglucosamine sulfohydrolase 10.7
estrogen sulfotransferase 10.6
glycosulfatase 10.5
glycuronidase 10.3
iduronate-2-sulfatase 10.3
CMP-sialic acid:lactosylceramide sialyltransferase 10.3
chondroitinase 10.2
heparan-alpha-glucosaminide N-acetyltransferase 9.7
estrogen sulfotransferase 9.6
trimetaphosphatase 9.5
GSase 9.3
lactaldehyde dehydrogenase 9.2
beta-glycerophosphatase 9.1
phosphonoacetate hydrolase 9.0
phosphoamidase 9.0
beta-glucuronidase 8.9
arylsulfate sulfotransferase 8.9
galactocerebrosidase 8.9
chondroitin 4-sulfotransferase 8.8
nicotinamidase 8.8
alpha-N-acetylglucosaminidase 8.7
alpha-L-iduronidase 8.6
choline dehydrogenase 8.6
N-acetylglucosaminylphosphotransferase 8.5
N-acetylgalactosaminidase 8.5
GDPase 8.5
17beta-HSD 8.4
phosphonatase 8.4
more...
Compound
N-Acetylgalactosamine 6-sulfate 13.3
2-(2,4-dichlorophenoxy)ethanol 13.3
2-(2,4-dichlorophenoxy)ethyl 13.3
Thyroxine sulfate 13.3
2-Hydroxyphenacetin 13.3
N-Acetylglucosamine 6-sulfate 13.3
2-(2,4-dichlorophenoxy)ethyl 13.3
2-(2,4-dichlorophenoxy)ethyl 13.3
2-(2,4-dichlorophenoxy)ethyl 13.3
UDP-N-acetylgalactosamine 4-sulfate 12.7
Formylglycine 11.9
Sinalbin 11.7
Demegestone 11.7
4-Methylumbelliferyl sulfate 11.7
L-Cysteic acid 11.3
Promazine hydrochloride 11.3
3-hydroxy-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one 11.3
Sinalbin 11.3
alpha-Zearalenol 11.3
Testosterone acetate 10.7
Hydroxycitronellal 10.7
Pronethalol 10.7
7-Hydroxyflavone 10.7
16 alpha-hydroxypregnenolone 10.6
sulfamoyl chloride 10.5
Sulfatide 10.0
3-T1 10.0
Sodium picosulfate 10.0
1,2,3,4-tetrahydrophenanthrene 10.0
Promegestone 9.8
6-hydroxy-2-naphthoic acid 9.8
Diiodothyronine 9.7
Cholesterol sulfate 9.6
Norathyriol 9.2
11beta-hydroxyandrosterone 9.2
Premarin 9.2
iduronate 9.1
7-methoxy-2H-chromen-2-one 9.1
Fast Garnet GBC 9.0
Equilenin 8.9
more...