Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.6.1 (sulfatase)
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Human Gene/Protein
arylsulfatase A 13.3
Gal-NAc6S 13.3
arylsulfatase 13.3
ARSK 13.3
heat shock 70kDa protein 2 13.3
MPS4A 13.3
sulfatase 13.3
steroid sulfatase (STS) 13.1
arylsulfatase B 13.0
SUMF1 protein 12.9
Arylsulfatase G 12.9
Sulfatase modifying factor 1 12.7
Arylsulfatase B 12.6
ARSB 12.5
sulfatase modifying factor 1 12.5
GALNS protein 12.3
estrone sulfatase 12.3
sulfatase modifying factor 2 12.3
cerebroside sulfate activator protein 12.3
ARSJ 12.3
more...
Disease
MPS VIII 13.3
Deficiency of arylsulfatase 13.0
MPS VI 11.7
MPS IIID 11.6
metachromatic leukodystrophy 11.5
torsion spasm 11.0
Morquio A syndrome 10.7
Rud syndrome 10.4
MPS IIIA 10.0
Morquio 9.7
MSD 9.7
Sanfilippo 9.6
lysosomal storage disease 9.4
mucopolysaccharidosis 9.3
Brailsford 9.1
Sanfilippo syndrome 9.1
CDPX1 9.0
MPS II 9.0
sphingolipidosis 8.9
ML III 8.8
more...
Symptom
Macula 6.4
scaly skin 5.9
Neurologic symptoms 5.8
disturbed balance 5.4
joint stiffness 5.2
ataxic gait 5.2
meningism 4.9
hepatosplenomegaly 4.9
Spots 4.5
lightheadedness 4.3
hypotonia 4.1
neck stiffness 4.0
anosmia 3.7
cerebellar ataxia 3.5
spasticity 3.4
hepatomegaly 3.4
Stiffness 3.3
dry skin 3.3
microbial colonization 3.2
abnormal gait 3.1
more...
Drug
Galsulfase 12.3
Sodium picosulfate 9.7
Sulfamide 9.2
Gardenia fruit 9.1
Equilenin 9.1
Calcium citrate 8.7
Pizotifen 8.6
Tibolone 8.3
Nabilone 7.6
Sodium ascorbate 7.5
NYS 7.5
Polysorbate 20 7.4
Chloramine T 7.4
Dienogest 7.0
Micafungin 6.6
Tramal 6.6
Perphenazine 6.6
beta-Galactosidase 6.5
Trilostane 6.5
Estriol 6.5
more...
Enzyme
sulfatase 13.3
choline-sulfatase 13.3
arylsulfatase A 13.3
galactose-6-sulfatase 13.0
arylsulfatase 12.9
N-acetylglucosamine-6-sulfatase 12.2
chondro-6-sulfatase 12.0
3-KSR 11.7
glucuronate-2-sulfatase 11.7
chondro-4-sulfatase 11.1
phosphoglycerol transferase 11.1
EC 5.4.99.15 11.0
N-sulfoglucosamine sulfohydrolase 10.7
estrogen sulfotransferase 10.6
glycosulfatase 10.5
glycuronidase 10.3
iduronate-2-sulfatase 10.3
CMP-sialic acid:lactosylceramide sialyltransferase 10.3
chondroitinase 10.2
heparan-alpha-glucosaminide N-acetyltransferase 9.7
more...
Compound
2-(2,4-dichlorophenoxy)ethyl 13.3
N-Acetylglucosamine 6-sulfate 13.3
N-Acetylgalactosamine 6-sulfate 13.3
2-Hydroxyphenacetin 13.3
2-(2,4-dichlorophenoxy)ethyl 13.3
Thyroxine sulfate 13.3
2-(2,4-dichlorophenoxy)ethyl 13.3
2-(2,4-dichlorophenoxy)ethanol 13.3
2-(2,4-dichlorophenoxy)ethyl 13.3
UDP-N-acetylgalactosamine 4-sulfate 12.7
Formylglycine 11.9
Sinalbin 11.7
Demegestone 11.7
4-Methylumbelliferyl sulfate 11.7
L-Cysteic acid 11.3
3-hydroxy-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one 11.3
alpha-Zearalenol 11.3
Promazine hydrochloride 11.3
Sinalbin 11.3
Pronethalol 10.7
more...