Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: EC:3.1.4.3 (phospholipase C)
18,461 document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein PLC 1685 Mol 1430 Sep 1363 phosphatidylinositol-specific 1299 ATP 1088 phospholipase A2 949 GTP 944 phospholipase D 835 tyrosine kinase 733 adenylate cyclase 666 endoplasmic reticulum 666 adenylyl cyclase 661 thrombin 572 ADP 538 insulin 530 PKC 523 AMP 521 phospholipase 505 phosphoinositide-specific 473 calmodulin 463 bradykinin 420 angiotensin II 368 phosphatidylinositol 3-kinase 348 Phospholipase C 332 membrane-bound 310 ATPase 304 phosphatase 303 epidermal growth factor 278 ERK1 277 PtdIns 276 vasopressin 267 cyclooxygenase 264 collagen 263 GDP 260 glycoprotein 259 muscarinic receptor 254 cytokine 248 protein kinase C inhibitor 247 platelet-derived growth factor 240 lipase 236 p38 233 polypeptide 228 PIP 225 G protein-coupled receptor 223 alkaline phosphatase 222 Rho 217 GTPase 209 ERK 206 mitogen-activated protein 201 Pseudomonas 197 GTP-binding protein 195 extracellular signal-regulated kinase 195 SDS 194 Ins 192 endothelin-1 187 Ang II 185 MAPK 184 metabotropic glutamate receptor 184 pleckstrin 179 phosphodiesterase 174 phosphoinositide 3-kinase 169 protein tyrosine kinase 166 beta 1 159 lipopolysaccharide 157 substance P 155 microsomal 153 MAP kinase 152 gamma2 152 nitric oxide synthase 149 calcium channel 146 bombesin 143 epidermal growth factor receptor 142 membrane protein 138 lipoxygenase 135 PKA 132 MEK 132 neuraminidase 127 Gen 127 5-hydroxytryptamine 125 P2Y2 124 more...

Disease pertussis 1399 cancer 416 tumor 383 cholera 251 SDS 194 hypertension 182 neuroblastoma 170 leukemia 149 depression 141 diabetes 137 glioma 111 ATM 111 ischemia 111 Alzheimer's disease 109 carcinoma 93 breast cancer 89 astrocytoma 80 atherosclerosis 80 lymphoma 75 gas gangrene 73 cystic fibrosis 73 osteosarcoma 73 hepatocellular carcinoma 72 cold 70 asthma 61 prostate cancer 58 sepsis 55 Blocking 54 uterus 51 melanoma 49 carcinogenesis 49 schizophrenia 49 infectious diseases 48 pheochromocytoma 47 sepsis 46 MCF 42 PAF 41 tumor growth 38 Mycobacterium 38 adenocarcinoma 38 obesity 37 Infection 35 tumorigenesis 35 squamous cell carcinoma 35 stroke 34 tuberculosis 33 HIV 33 immunodeficiency 33 type 2 diabetes 32 tumor progression 32 SEM 32 enteritis 32 NAME 31 paroxysmal nocturnal hemoglobinuria 30 plaque 30 rheumatoid arthritis 30 heart failure 30 pneumonia 29 mole 29 glioblastoma 29 mole 29 MRS 29 erythroleukemia 29 epilepsy 28 Pituitary 28 Steroids 28 cardiovascular disease 27 Bordetella 25 lung cancer 25 tetanus 25 acute promyelocytic leukemia 25 essential hypertension 24 ovarian cancer 24 cytomegalovirus 23 infertility 23 bipolar disorder 23 Parkinson's disease 23 colon cancer 23 idiopathic thrombocytopenic purpura 22 bacterial infection 22 more...

Symptom pain 134 seizures 35 starvation 33 diarrhea 28 bitter taste 16 analgesia 15 collapse 14 rundown 13 anesthesia 12 respiratory distress 9 ataxia 8 exhaustion 7 hypothermia 6 functional recovery 6 anorexia 5 spasm 5 erythema 5 hypercapnia 4 twitching 4 weakness 4 dry eye 4 acute pain 4 fasciculation 4 acidity 3 tremor 3 hyperoxia 3 cachexia 3 blackout 3 memory loss 2 overweight 2 acute stress 2 insomnia 2 regurgitation 2 spasticity 2 splenomegaly 2 agitation 2 syncope 2 HSA 2 fatigue 2 despair 2 constipation 2 ophthalmoplegia 2 male subfertility 2 thinning 2 dizziness 1 Anoxia 1 sleepiness 1 cerebellar ataxia 1 ENT 1 emaciation 1 muscle cramps 1 hypocapnia 1 paresthesia 1 hypertonia 1 Neuropathic pain 1 myalgia 1 chills 1 hyperacusis 1 vomiting 1 hypotonia 1 rhinorrhea 1 discomfort 1 angina 1 tinnitus 1 muscle rigidity 1 urinary frequency 1 sneezing 1 chest pain 1 nausea 1 paresis 1 apathy 1 clonus 1 impaired motor coordination 1 numbness 1 discomfort 1 Easy bruising 1 rigors 1 abdominal pain 1 Inflammatory pain 1 skin damage 1 more...

Drug caffeine 138 Angiotensin II 98 Histamine 75 IL-2 70 MAP 68 lysine 66 Dermatol 63 Cardiovasc 62 ETA 60 CaCl2 55 CaCl2 55 CaCl2 55 PTH 50 Nephron 46 Ethanol 44 Forskolin 43 ROS 41 Gel 38 Asn 36 Indomethacin 34 ICI 34 IFN-gamma 32 CSF 30 Pronase 26 CTX 21 CDP 20 NADH 19 Glucagon 18 uPA 17 EE2 17 Atropine 17 p75 16 ABC 16 -deoxyadenosine 12 vitamin E 12 lactose 11 Leaf 10 Retinoic acid 10 GHRP 9 DNase I 9 K-252a 9 pyridoxal phosphate 9 Quisqualate 9 Adenosine triphosphate 8 Phosphatidylserine 8 CTX 7 CTX 7 ascorbate 7 Growth hormone 7 Fenoldopam 7 Growth hormone 7 Ouabain 7 Portal 6 Luteinizing 6 Itraconazole 6 Clonidine 6 Silica 6 AraC 6 Sodium nitroprusside 6 Iloprost 6 Nephron 6 MRC 6 ENT 6 Propofol 5 Monensin 5 CCL 5 NAG 5 CAM 5 NH3 5 BLM 5 CoCl2 5 Trifluoperazine 5 Secretin 5 CoCl2 5 PCP 5 Urokinase 4 Doyle 4 balanced salt solution 4 TAT 4 GRF 4 more...

Enzyme phospholipase C 18461 protein kinase C 3614 phospholipase A2 1222 protein kinase 1182 mitogen-activated protein kinase 1048 phospholipase D 829 adenylate cyclase 710 thrombin 561 ERK 353 phosphatidylinositol 3-kinase 349 ATPase 336 trypsin 277 alkaline phosphatase 254 lipase 244 focal adhesion kinase 227 MEK 208 phosphodiesterase 178 phosphoinositide 3-kinase 169 lipoprotein lipase 161 PI-PLC 153 calcineurin 150 neuraminidase 150 diacylglycerol kinase 145 lipoxygenase 136 guanylate cyclase 123 NADPH oxidase 107 NADPH oxidase 100 acetylcholinesterase 99 AMPK 98 luciferase 81 CaMKII 79 myosin light chain kinase 74 NO synthase 73 phosphatidylinositol 4-kinase 73 acid phosphatase 73 elastase 64 collagenase 61 caspase-3 60 peroxidase 57 superoxide dismutase 56 5'-nucleotidase 54 glutathione S-transferase 54 urokinase-type plasminogen activator 54 RNase 50 reverse transcriptase 50 lactate dehydrogenase 49 catalase 46 RNase 46 chymotrypsin 45 PARP 43 MAP 40 neuropathy target esterase 40 renin 39 papain 39 apyrase 37 phospholipase A1 37 CPT 36 DNase 35 hyaluronidase 35 PKG 35 ADP-ribosyltransferase 34 thromboplastin 32 monoacylglycerol lipase 32 proteinase K 31 sphingosine kinase 31 ADP-ribosyltransferase 31 transglutaminase 30 GRK5 29 PIP kinase 29 hexosaminidase 28 aequorin 28 plasmin 28 creatine kinase 28 AMP-activated protein kinase 27 protein phosphatase 2A 27 MDP 27 RNA polymerase 27 GRK2 26 phosphorylase 26 hyaluronidase 26 more...

Compound calcium 6064 phosphate 1744 tyrosine 1435 Dec 1364 cAMP 1202 ATP 1094 acetate 1011 GTP 947 sodium 854 DNA 719 ADP 585 AMP 542 ADP 539 ADP 539 glucose 465 glycerol 423 glutamate 401 Clin 383 water 363 oxygen 322 Phosphatidylinositol 317 Phe 309 Triton X-100 291 arginine 285 serine 282 GDP 266 Ins(1,4,5)P3 265 potassium 262 cGMP 257 sulfate 248 nitric oxide 247 COS 232 ethanol 229 leucine 225 UTP 225 Mg2+ 207 SDS 202 5-HT 191 PMA 189 PMA 185 noradrenaline 177 threonine 175 salt 170 alanine 161 zinc 151 EDTA 146 EDTA 146 galactose 141 caffeine 138 prostacyclin 138 methionine 131 Inositol 131 hydrogen 130 lysine 129 cysteine 129 manganese 127 1H-pyrrole-2,5-dione 125 Thrombin 125 MEK 122 tryptophan 122 PGE2 120 Carbachol 118 Angiotensin II 111 Ang II 104 bromide 101 NH2 99 H2O2 96 GABA 93 GABA 91 aldosterone 89 TPA 89 His 89 TPA 89 Bradykinin 88 palmitic acid 86 DAD 85 DAG 85 ammonium 84 ACh 82 palmitic acid 82 more...

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