Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.4.3 (phospholipase C)
18,461 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PLC 1685
Mol 1430
Sep 1363
phosphatidylinositol-specific 1299
ATP 1088
phospholipase A2 949
GTP 944
phospholipase D 835
tyrosine kinase 733
endoplasmic reticulum 666
adenylate cyclase 666
adenylyl cyclase 661
thrombin 572
ADP 538
insulin 530
PKC 523
AMP 521
phospholipase 505
phosphoinositide-specific 473
calmodulin 463
bradykinin 420
angiotensin II 368
phosphatidylinositol 3-kinase 348
Phospholipase C 332
membrane-bound 310
ATPase 304
phosphatase 303
epidermal growth factor 278
ERK1 277
PtdIns 276
vasopressin 267
cyclooxygenase 264
collagen 263
GDP 260
glycoprotein 259
muscarinic receptor 254
cytokine 248
protein kinase C inhibitor 247
platelet-derived growth factor 240
lipase 236
more...
Disease
pertussis 1399
cancer 416
tumor 383
cholera 251
SDS 194
hypertension 182
neuroblastoma 170
leukemia 149
depression 141
diabetes 137
glioma 111
ischemia 111
ATM 111
Alzheimer's disease 109
carcinoma 93
breast cancer 89
astrocytoma 80
atherosclerosis 80
lymphoma 75
gas gangrene 73
cystic fibrosis 73
osteosarcoma 73
hepatocellular carcinoma 72
cold 70
asthma 61
prostate cancer 58
sepsis 55
Blocking 54
uterus 51
carcinogenesis 49
schizophrenia 49
melanoma 49
infectious diseases 48
pheochromocytoma 47
sepsis 46
MCF 42
PAF 41
tumor growth 38
adenocarcinoma 38
Mycobacterium 38
more...
Symptom
pain 134
seizures 35
starvation 33
diarrhea 28
bitter taste 16
analgesia 15
collapse 14
rundown 13
anesthesia 12
respiratory distress 9
ataxia 8
exhaustion 7
hypothermia 6
functional recovery 6
spasm 5
anorexia 5
erythema 5
weakness 4
twitching 4
dry eye 4
acute pain 4
fasciculation 4
hypercapnia 4
blackout 3
hyperoxia 3
acidity 3
tremor 3
cachexia 3
regurgitation 2
overweight 2
acute stress 2
syncope 2
male subfertility 2
constipation 2
memory loss 2
ophthalmoplegia 2
agitation 2
splenomegaly 2
spasticity 2
HSA 2
more...
Drug
caffeine 138
Angiotensin II 98
Histamine 75
IL-2 70
MAP 68
lysine 66
Dermatol 63
Cardiovasc 62
ETA 60
CaCl2 55
CaCl2 55
CaCl2 55
PTH 50
Nephron 46
Ethanol 44
Forskolin 43
ROS 41
Gel 38
Asn 36
Indomethacin 34
ICI 34
IFN-gamma 32
CSF 30
Pronase 26
CTX 21
CDP 20
NADH 19
Glucagon 18
Atropine 17
uPA 17
EE2 17
ABC 16
p75 16
-deoxyadenosine 12
vitamin E 12
lactose 11
Leaf 10
Retinoic acid 10
GHRP 9
K-252a 9
more...
Enzyme
phospholipase C 18461
protein kinase C 3614
phospholipase A2 1222
protein kinase 1182
mitogen-activated protein kinase 1048
phospholipase D 829
adenylate cyclase 710
thrombin 561
ERK 353
phosphatidylinositol 3-kinase 349
ATPase 336
trypsin 277
alkaline phosphatase 254
lipase 244
focal adhesion kinase 227
MEK 208
phosphodiesterase 178
phosphoinositide 3-kinase 169
lipoprotein lipase 161
PI-PLC 153
neuraminidase 150
calcineurin 150
diacylglycerol kinase 145
lipoxygenase 136
guanylate cyclase 123
NADPH oxidase 107
NADPH oxidase 100
acetylcholinesterase 99
AMPK 98
luciferase 81
CaMKII 79
myosin light chain kinase 74
acid phosphatase 73
NO synthase 73
phosphatidylinositol 4-kinase 73
elastase 64
collagenase 61
caspase-3 60
peroxidase 57
superoxide dismutase 56
more...
Compound
calcium 6064
phosphate 1744
tyrosine 1435
Dec 1364
cAMP 1202
ATP 1094
acetate 1011
GTP 947
sodium 854
DNA 719
ADP 585
AMP 542
ADP 539
ADP 539
glucose 465
glycerol 423
glutamate 401
Clin 383
water 363
oxygen 322
Phosphatidylinositol 317
Phe 309
Triton X-100 291
arginine 285
serine 282
GDP 266
Ins(1,4,5)P3 265
potassium 262
cGMP 257
sulfate 248
nitric oxide 247
COS 232
ethanol 229
leucine 225
UTP 225
Mg2+ 207
SDS 202
5-HT 191
PMA 189
PMA 185
more...