Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: EC:3.1.4.3 (
phospholipase C
)
18,461
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
PLC
1685
Mol
1430
Sep
1363
phosphatidylinositol-specific
1299
ATP
1088
phospholipase A2
949
GTP
944
phospholipase D
835
tyrosine kinase
733
endoplasmic reticulum
666
adenylate cyclase
666
adenylyl cyclase
661
thrombin
572
ADP
538
insulin
530
PKC
523
AMP
521
phospholipase
505
phosphoinositide-specific
473
calmodulin
463
bradykinin
420
angiotensin II
368
phosphatidylinositol 3-kinase
348
Phospholipase C
332
membrane-bound
310
ATPase
304
phosphatase
303
epidermal growth factor
278
ERK1
277
PtdIns
276
vasopressin
267
cyclooxygenase
264
collagen
263
GDP
260
glycoprotein
259
muscarinic receptor
254
cytokine
248
protein kinase C inhibitor
247
platelet-derived growth factor
240
lipase
236
more...
Disease
pertussis
1399
cancer
416
tumor
383
cholera
251
SDS
194
hypertension
182
neuroblastoma
170
leukemia
149
depression
141
diabetes
137
glioma
111
ischemia
111
ATM
111
Alzheimer's disease
109
carcinoma
93
breast cancer
89
astrocytoma
80
atherosclerosis
80
lymphoma
75
gas gangrene
73
cystic fibrosis
73
osteosarcoma
73
hepatocellular carcinoma
72
cold
70
asthma
61
prostate cancer
58
sepsis
55
Blocking
54
uterus
51
carcinogenesis
49
schizophrenia
49
melanoma
49
infectious diseases
48
pheochromocytoma
47
sepsis
46
MCF
42
PAF
41
tumor growth
38
adenocarcinoma
38
Mycobacterium
38
more...
Symptom
pain
134
seizures
35
starvation
33
diarrhea
28
bitter taste
16
analgesia
15
collapse
14
rundown
13
anesthesia
12
respiratory distress
9
ataxia
8
exhaustion
7
hypothermia
6
functional recovery
6
spasm
5
anorexia
5
erythema
5
weakness
4
twitching
4
dry eye
4
acute pain
4
fasciculation
4
hypercapnia
4
blackout
3
hyperoxia
3
acidity
3
tremor
3
cachexia
3
regurgitation
2
overweight
2
acute stress
2
syncope
2
male subfertility
2
constipation
2
memory loss
2
ophthalmoplegia
2
agitation
2
splenomegaly
2
spasticity
2
HSA
2
more...
Drug
caffeine
138
Angiotensin II
98
Histamine
75
IL-2
70
MAP
68
lysine
66
Dermatol
63
Cardiovasc
62
ETA
60
CaCl2
55
CaCl2
55
CaCl2
55
PTH
50
Nephron
46
Ethanol
44
Forskolin
43
ROS
41
Gel
38
Asn
36
Indomethacin
34
ICI
34
IFN-gamma
32
CSF
30
Pronase
26
CTX
21
CDP
20
NADH
19
Glucagon
18
Atropine
17
uPA
17
EE2
17
ABC
16
p75
16
-deoxyadenosine
12
vitamin E
12
lactose
11
Leaf
10
Retinoic acid
10
GHRP
9
K-252a
9
more...
Enzyme
phospholipase C
18461
protein kinase C
3614
phospholipase A2
1222
protein kinase
1182
mitogen-activated protein kinase
1048
phospholipase D
829
adenylate cyclase
710
thrombin
561
ERK
353
phosphatidylinositol 3-kinase
349
ATPase
336
trypsin
277
alkaline phosphatase
254
lipase
244
focal adhesion kinase
227
MEK
208
phosphodiesterase
178
phosphoinositide 3-kinase
169
lipoprotein lipase
161
PI-PLC
153
neuraminidase
150
calcineurin
150
diacylglycerol kinase
145
lipoxygenase
136
guanylate cyclase
123
NADPH oxidase
107
NADPH oxidase
100
acetylcholinesterase
99
AMPK
98
luciferase
81
CaMKII
79
myosin light chain kinase
74
acid phosphatase
73
NO synthase
73
phosphatidylinositol 4-kinase
73
elastase
64
collagenase
61
caspase-3
60
peroxidase
57
superoxide dismutase
56
more...
Compound
calcium
6064
phosphate
1744
tyrosine
1435
Dec
1364
cAMP
1202
ATP
1094
acetate
1011
GTP
947
sodium
854
DNA
719
ADP
585
AMP
542
ADP
539
ADP
539
glucose
465
glycerol
423
glutamate
401
Clin
383
water
363
oxygen
322
Phosphatidylinositol
317
Phe
309
Triton X-100
291
arginine
285
serine
282
GDP
266
Ins(1,4,5)P3
265
potassium
262
cGMP
257
sulfate
248
nitric oxide
247
COS
232
ethanol
229
leucine
225
UTP
225
Mg2+
207
SDS
202
5-HT
191
PMA
189
PMA
185
more...