Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: EC:3.1.4.3 (phospholipase C)
 18,461 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PLC 1685
Mol 1430
Sep 1363
phosphatidylinositol-specific 1299
ATP 1088
phospholipase A2 949
GTP 944
phospholipase D 835
tyrosine kinase 733
endoplasmic reticulum 666
adenylate cyclase 666
adenylyl cyclase 661
thrombin 572
ADP 538
insulin 530
PKC 523
AMP 521
phospholipase 505
phosphoinositide-specific 473
calmodulin 463
more...
Disease
pertussis 1399
cancer 416
tumor 383
cholera 251
SDS 194
hypertension 182
neuroblastoma 170
leukemia 149
depression 141
diabetes 137
glioma 111
ischemia 111
ATM 111
Alzheimer's disease 109
carcinoma 93
breast cancer 89
atherosclerosis 80
astrocytoma 80
lymphoma 75
osteosarcoma 73
more...
Symptom
pain 134
seizures 35
starvation 33
diarrhea 28
bitter taste 16
analgesia 15
collapse 14
rundown 13
anesthesia 12
respiratory distress 9
ataxia 8
exhaustion 7
hypothermia 6
functional recovery 6
erythema 5
anorexia 5
spasm 5
dry eye 4
acute pain 4
weakness 4
more...
Drug
caffeine 138
Angiotensin II 98
Histamine 75
IL-2 70
MAP 68
lysine 66
Dermatol 63
Cardiovasc 62
ETA 60
CaCl2 55
CaCl2 55
CaCl2 55
PTH 50
Nephron 46
Ethanol 44
Forskolin 43
ROS 41
Gel 38
Asn 36
ICI 34
more...
Enzyme
phospholipase C 18461
protein kinase C 3614
phospholipase A2 1222
protein kinase 1182
mitogen-activated protein kinase 1048
phospholipase D 829
adenylate cyclase 710
thrombin 561
ERK 353
phosphatidylinositol 3-kinase 349
ATPase 336
trypsin 277
alkaline phosphatase 254
lipase 244
focal adhesion kinase 227
MEK 208
phosphodiesterase 178
phosphoinositide 3-kinase 169
lipoprotein lipase 161
PI-PLC 153
more...
Compound
calcium 6064
phosphate 1744
tyrosine 1435
Dec 1364
cAMP 1202
ATP 1094
acetate 1011
GTP 947
sodium 854
DNA 719
ADP 585
AMP 542
ADP 539
ADP 539
glucose 465
glycerol 423
glutamate 401
Clin 383
water 363
oxygen 322
more...